FEXOSTAD 180 Stella medicine treats allergic rhinitis, chronic urticaria (10 tablets)

Dosage form Film bag tablets
Specifications Box of 1 blister x 10 tablets
Ingredient Fexofenadine hydrochloride
Indication Allergic rhinitis, urticaria, itching

Ingredient

Composition information	Content
Fexofenadine hydrochloride	180mg

Uses

Indications

Fexostad 180 medicine is indicated in the following cases:

Reduce symptoms of seasonal allergic rhinitis in adults and children 12 years of age.

Treatment of non -complicated skin symptoms of rash urticaria Unfinished in adults and children aged 12 and older.

Pharmacy

fexofenadin hydrochloride is an antihistamine drug that has a selective antagonistic effect on peripheral H1 receptors. The two optical contrast forms of fexofenadin hydrochloride have almost similar antihistamine resistance. The drug does not cause sleep or affects the central nervous system.

Dynamic pharmacy

Fexofenadin is quickly absorbed after drinking with peaks in plasma achieved for 2-3 hours. About 60 - 70% linked to plasma proteins. About 5% of the total dose is metabolized, mostly by the intestinal mucosa, only 0.5 - 1.5% of the dosage is metabolized in the liver by the cytochrom P450 system.

Selling time for about 14 hours has been reported, although it can last for patients with renal failure. Elimination mainly in feces and only 10% present in urine. Fexofenadin does not pass through the brain barrier. Fexofenadin is a metabolite of terfenadin and thus found in breast milk after using terfenadin.

Before taking FEXOSTAD 180 Stella medicine treats allergic rhinitis, chronic urticaria (10 tablets)

How to use

Fexostad 180mg is used by oral and oral before meals.

Dosage

Adults and children aged 12 years and older: 180mg (1 tablet) x 1 time/day.

Children under 12 years: The effectiveness and safety of Fexofenadin Hydrochorid has not been studied in children under 12 years old.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Symptoms

Information about fexofenadin level toxicity in humans is limited; However, dizziness, drowsiness and dry mouth have been reported. Single dose of fexofenadin hydrochloride up to 800 mg and fexofenadin hydrochloride dose 690mg x 2 times/day for 1 month or 240mg x 1 time/day for 1 year is well tolerated in adults.

Treatment

To treat overdose Fexofenadin, it is necessary to take common measures to eliminate the drug that has not been absorbed from the digestive tract and should take supportive treatment and symptomatic treatment. Experience with precursor terfenadin shows that fexofenadin is not significantly eliminated by hemolysis.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when forgetting a dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Fexostad 180, you may experience unwanted effects (ADR).

Common

Nervous system: headache , drowsiness, dizziness .

digestive: nausea.

Less

Body: Fatigue.

Unknown frequency occurs

The immune system: Hypersensitivity reactions to manifestations such as angioedema, chest tightness, shortness of breath, blush and anaphylaxis.

Mental: Insomnia, Anxiety and Sleep disorders or nightmares (Paroniria symptoms). Cardiovascular: Heart beat fast , brushing chest drum. Digestive: diarrhea . skin and subcutaneous tissues: rash, urticaria, itching.

When encountering side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Fexostad 180 drugs contraindicated in the following cases:

Patients with hypersensitivity to fexofenadin hydrochloride or any ingredients of the drug.

Be cautious when using

although clinical experience in general does not show any differences in response to drugs between older and young patients, it should be noted that Fexofenadin is significantly eliminated through the kidneys and the risk of severe side effects may increase in patients with renal insufficiency. Because older patients may be impaired renal function, the test of renal function can be helpful and need to be cautious when choosing the dosage for these patients.

Although fexofenadin has no toxic effect on the heart like Terfenadin, Fexofenadin is associated with increased QTC, fainting and ventricular arrhythmia on at least one patient at risk of cardiovascular disease before.

Patients using preparations containing fexofenadin hydrochloride in combination with pseudoephedrin hydrochloride should be instructed only by doctor's prescription medication and not exceeding the prescribed dose. Patients should not arbitrarily use other antihistamines or nasal pills. If worried, dizzy, or drowsiness occurs during treatment, patients should stop using the drug in the form of coordination and consulting doctor.

The ability to drive and operate machinery

Based on the pharmacological data and side effects have been reported, Fexofenadin hydrochloride tablets are less likely to influence on driving and operating machinery. Objective tests show that Fexofenadin has no significant effects on the function of the central nervous system. This means that patients can drive or do jobs that require concentration. However, in order to detect sensitive people with abnormal reactions to the drug, it is advisable to check personal response before driving or perform complex tasks.

Pregnancy

so far has not had adequate and controlled studies on the use of fexofenadin hydrochloride in pregnant women and should only use fexofenadin hydrochloride during pregnancy when the treatment is greater than the risk for the fetus.

Lactation period

Currently, there is no adequate and controlled research on the use of fexofenadin during breastfeeding and due to many drugs that are secreted into breast milk, so be careful when using fexofenadin in breastfeeding women and should stop breastfeeding or stopping medicine.

Medicinal interaction

antifungal, antibacterial (ketoconazol, erythromycin ): There is no side effects or any clinical QT changes reported after simultaneous use Recognize the increase in fexofenadin levels in plasma in drug interaction studies.

Demons from studies in vito and in vivo in animals show that erythromycin and ketoconazole increase the absorption of fexofenadin when used simultaneously, possibly due to the effects on the mechanism of transportation systems such as P-Glycoprotein. Fexofenadin does not change the pharmacokinetics of erythromycin or ketoconazole.

Anti -acid: antacids containing aluminum and Magnesi hydroxyd reduces fexofenadin absorption. Therefore, Fexofenadin should not be used and antacids containing aluminum and magnesium close together.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

To be out of reach of children.

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