Floxaval 500mg Delorbis Treatment of infection (10 tablets)

Dosage form Box of 1 blister x 10 tablets
Specifications Levofloxacin

Ingredient

Composition information	Content
Levofloxacin	500mg

Uses

levofloxacin is indicated to treat cases of infections caused by bacteria sensitive to levofloxacin caused by the following:
- Acute sinusitis.
- The acute drama of chronic bronchitis.
- Pneumonia is suffering from the community.
- Urinary tract infections have complications, including nephritis.
- Skin and software infections.

Before taking Floxaval 500mg Delorbis Treatment of infection (10 tablets)

How to use

oral medication. - Levofloxacin pill needs to be swallowed, not crushed, with a sufficient amount of water. The drug may break the eye for the dose. The drug can be taken during meals or between two meals.

Dosage

Dosage and sugar are used depending on the type and weight of infections and the sensitivity of the pathogens are suspected. In case of initial treatment with intravenous tract with Levofloxacin infusion solution (patients are not suitable for oral route), after a few days can be transferred from venous tract at first to oral use in the same dosage, depending on the condition of the patient.
Dosage, treatment time and adult sugar with normal renal function (Creatinine clearance> 50 ml/minute):
- Acute sinusitis: Take 500 mg once a day for 10 to 14 days.
- Acute drama of chronic bronchitis: Take 250 - 500 mg once a day for 7 to 10 days.
- Pneumonia is suffering from the community: Take 500 mg daily once or twice for 7 to 14 days.
- Urinary tract infections have complications including nephritis: Take 250 mg once a day for 7 to 10 days. In case of severe infections, it is advisable to consider increasing the dose by intravenously.
- Skin infections and software: Take 250 mg once a day or 500 mg once or twice a day for 7 to 14 days. However, special attention should be paid to the kidney function in the elderly patients, and only need to adjust the dosage accordingly.

What to do when overdose?

According to animal toxicity studies, the most important signs that can be seen after an acute levofloxacin overdose are symptoms of the central nervous system such as confusion, tinnitus, perceived disorders and seizures. If overdose occurs, symptomatic treatment should be treated. Hemolysis, including abdominal and Capd dung (continuous peritoneal fertilizer), does not work to eliminate levofloxacin from the body. There is no specific antidote. Bowel should be washed and antacid medications to protect the stomach lining.

What to do when you forget 1 dose?

If you forget a dose, use it as soon as possible. However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that double dose should not be used.

Side Effects

The frequency of unwanted effects: Common: (> 1/100 and 1/1000 and 1/10,000 and The following unwanted effects may occur when using levofloxacin:

digestive system:

Common: Nausea, diarrhea. Less common: anorexia, vomiting, indigestion (severe abdominal), abdominal pain. Rarely: Bloody diarrhea in some very rare cases may be inflammation of the colon, including fake colitis (severe colitis). Very rare: Hypoglycemia (reducing blood sugar) especially in diabetics.
Reaction skin and allergies: rarely: rash, itching; Rare: urticaria, bronchospasm/shortness of breath; Very rare: Quincke edema (face, tongue, throat or laryngeal), lower blood pressure, anaphylaxis or anaphylactic (severe allergic reactions can cause sudden death), light sensitivity; In some cases, it is severe with severe herpes such as Stevens-Johnson syndrome (foreign and mucous puffiness), poisoned epidermal necrosis (lyell syndrome, skin puffiness reactions) and diverse skin redness (redness and puffiness). Skin-skin reactions and anaphylactic/anaphylactic reactions can sometimes occur after the first dose.

Nervous system:

Less: headache, tinnitus/dizziness, drowsiness and insomnia; Rarely: depression, fear, psychotic reactions (with hallucinations), paresthesia (abnormal feeling such as numbness, needle and burning), tremor, agitation, confusion, convulsions; Very rare: Peaceful (reducing sensitivity to irritation or decrease in sensory), visual and hearing disorders, taste disorders and smells.
Cardiovascular system: rare: tachycardia, hypotension; Very rare: anaphylaxis/anaphylactic variety. Very rare: The tendon, muscle weakness may be particularly important in patients with severe myasthenia gravis (a type of chronic progressive muscle disease); Some special cases have muscle pattern.

-Gan and kidney:Common

: Increasing liver enzymes (transaminase alat and asat); Uncommon: Increasing bilirubin and creatinin
very rare: hepatitis and acute renal failure.

-MOM:

Uncommon: Incretion of eosinophilia and leukopenia; Rarely: neutropenia and thrombocytopenia; Very rare: loss of granulocytes; In some cases, especially hemolytic anemia (the number of red blood cells decreases significantly) and the whole stream anemia (significantly reduces the number of all types of blood cells).

Other side effects: Uncommon: weakness, fungal infection and other anti -drug proliferation; Very rare: allergic pneumonia, fever. Other undesirable effects may be related to the Fluoroquinolone group: very rare: symptoms outside the tower and other disorders of muscle coordination, allergic vasculitis and porphyrin metabolic disorders in patients with this type of metabolic diseases.

Warnings

Prisable when using

- In patients with congenital convulsions, for example, in the case of sharing many drugs (see drug interactions), and like other quinolone, must be very careful when using levofloxacin.
- diarrhea, especially severe, persistent and/or bloody diarrhea, during and after treatment of levofloxacin, may be symptoms of clostridium difficile colitis. If suspected fake colitis, immediately stop using levofloxacin.
- Tailitis, limited to Quinolone, sometimes can lead to tendons, especially heel tendons (Achilles tendons). This unwanted effect occurs within 48 hours after the beginning of treatment and may occur on both sides. Older patients are more susceptible to tendonitis. The risk of tendons can be increased when used with corticosteroids. If the tendonitis is suspected, it is necessary to immediately stop treating levofloxacin and must let the tendon are hurting.
- In patients with renal impairment, levofloxacin dose must be adjusted because levofloxacin is excreted mainly through the kidneys.
- Although sensitive to light is very rare with levofloxacin, patients should not expose unnecessarily with dazzling sunlight or artificial ultraviolet rays.
- Like other antibiotics, using levofloxacin, especially for prolonged use, can make anti -drug microorganisms grow. It is necessary to assess the condition of the patient repeated many times. If superinfection occurs during treatment, appropriate measures should be applied.
-Patients with an active active enzyme glucose-6-phosphate dehydrogenase or really prone to blood-soluble reaction when treated with quinolone antibacterial drugs. It is necessary to consider this ability when using levofloxacin.
Driving and operating machine: Levofloxacin can cause unwanted effects such as tinnitus, dizziness, drowsiness and visual disorders, which can become a risk in cases such as driving or operating machine.

Drug interaction

There is no meaningful interaction with food. Two hours before or after taking Levofloxacin, do not take preparations containing two or three chemotherapy cations such as iron or anti-anti-acid salts containing magnesi or aluminum, because it can reduce absorption. Levofloxacin's bioavailability is significantly reduced when the drug is used with sucralfate, so only 2 hours of sucralfate should be taken after taking Levofloxacin.

Storage

No special storage conditions are required. Store below 30 degrees C.

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