Fluopas skin ointment reduces symptoms of inflammation and itching of skin diseases (10g)

Dosage form Tube x 10g
Specifications Fluocinolon acetonid

Ingredient

Composition information	Content
Fluocinolon acetonid	0.0025g

Uses

Indications

Fluopas 0.025% are indicated for treatment in the case: reducing symptoms of inflammation and itching of skin diseases responding to corticosteroids.

Pharmacokic

fluoronide fluoronide is a synthetic corticosteroid with fluor atom attached to the steroid nucleus. The mechanism of action of topical corticosteroids is due to a combination of three important properties: anti -inflammatory, anti -itching, and vasoconstrictor effect. The effect of the drug is at least somewhat due to the link with the steroid receptor. Corticosteroids reduce inflammation by stabilizing the lysosom membrane of leukemia, inhibit the concentration of macrophages in inflamed areas, reduce the adhesion of leukocytes with capillary endothelium, reduce capillary permeability, reduce complementary components, resist the effects of histamine and release kinine from the background, reduce the proliferation of fibroblasts, collagen sedimentation and then formation of tissue scars.

Pharmacokinetics

absorption

When used on the spot, corticosteroids on normal skin are intact, only a small amount of drugs reach the pit and then into the general circulatory system. However, the absorption increases significantly when the skin is lost Keratin, inflamed or/and other diseases in the epidermal fence (such as psoriasis, eczema). Depending on the level of permeability, the amount of topical and skin condition in the top of the drug, the drug is more absorbed in the scrotum, armpits, eyelids, face and scalp (about 36%) and is absorbed less at the forearm, knee, elbow, palms and soles of the feet (about 1%). Even after washing the drug, corticosteroids are still absorbed for a long time, possibly because the drug is kept in the horny layer.

Distribution

through the skin, the amount of drugs absorbed will be distributed into the skin, muscles, liver, intestines, and kidneys.

Metabolism

Corticosteroids are initially metabolized in the skin, a small amount is absorbed into the circulatory system and is metabolized in the liver into non -effective substances.

Elimination

The drug excreted through the kidneys is mainly in the form of glucuronid and sulfate, but also has an inexplicable amount. A small amount of metabolites except for feces.

Before taking Fluopas skin ointment reduces symptoms of inflammation and itching of skin diseases (10g)

How to use

Fluopas 0.025% are used on the skin.

Dosage

Apply the drug to the infected skin a thin layer 2-4 times/day depending on the level of damage. With a hairy position, hair should shave hair and hair to direct contact with damage; Closed bandages can be used in the treatment of psoriasis or recurrent disease condition when prescribed by a doctor. If an infection appears, it is necessary to remove the bandage and use an appropriate antibacterial drug.

What to do when overdose?

Stop drug if skin irritation or contact dermatitis during treatment.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

few side effects when using acetonid fluocinolone, but like other external steroids, occasionally encounter side effects such as sensitivity or irritation at the top of the drug.

Can be encountered: dry skin, folliculitis, hair, reduced skin pigmentation, skin atrophy, stretch marks, secondary infections, lumpy, red acne eggs, facial dermatitis, hypersensitivity. If you take the drug regularly, apply on a large scale, or use for a long time as well as when treating areas that are susceptible to braking or closed bandage, the drug is likely to cause the same consequences as the use of systemic sugar steroids.

Notify the doctor with unwanted effects when using the drug.

Stop drug if skin irritation or contact dermatitis during treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

sensitive to any ingredients of the drug.

Do not use for infections, tuberculosis, fungi and most skin virus infections (including herpes) have not been treated.

Be cautious when used

When using fluorone fluorone in wide skin, it is not advisable to be closed because of the increased risk of systemic poisoning.

can cause adrenal insufficiency in patients who take large quantities of drugs and apply on a large, long -term or icy.

People with psoriasis should be carefully monitored because the disease may worsen or create pus psoriasis.

Be cautious for patients with impaired T -cell function or other patients being treated with other immunodeficiency drugs.

Use fluorone fluoroneide for infection wounds without additional treatment antibiotics that can cause infection to spread.

Do not use eye small because there is a risk of glaucom caused by corticosteroids.

The drug can inhibit the hypothalamus - pituitary gland - adrenal gland, manifest: Cushing syndrome, hyperglycemia, urinary tract if the drug is used in large amounts, causing increased concentration during the system circulation, often recovered after stopping the drug.

Prolonged corticosteroids lead to skin atrophy and subcutaneous organization.

Local corticosteroids can lead to secondary infections. If the symptoms do not decrease in a few days to 1 week, the patient needs to be suspended and re -examined.

For children: Children are prone to pituitary -shaft impairment - adrenal glands and Cushing syndrome than adults because of the larger ratio of skin surface/weight. The manifestation of adrenal insufficiency includes growth slowly, not gaining weight. Therefore, limitations for children and hold at the minimum doses needed enough to achieve the effectiveness of treatment.

The ability to drive and operate machinery

drugs can be used for drivers and operating machinery.

Pregnancy

Experimental research shows that corticosteroids can cause teratogen in experimental animals. There is no adequate and well -controlled research on pregnant women. The drug is for pregnant women only when the benefits are at risk, and are not used in large quantities or prolonged time.

The period of breastfeeding

unknown topical corticosteroids are excreted in milk or not. With a whole body, corticosteroids excreted in milk in small amounts are not enough to harm the breastfeed. Be careful when using topical corticosteroids for breastfeeding women.

Drug interaction

has not found information about drug interaction with fluocinolon acetonid skin ointment.

Storage

Leave a cool dry place, avoid light, temperature below 30⁰C.

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