Fosmicin for I.V Use injection drugs for infections (10 vials)

Dosage form Box of 10 vials
Specifications Fosfomycin sodium

Ingredient

Composition information	Content
Fosfomycin sodium	1g

Uses

indications

Fosmicin for I.V Use injection drugs are indicated for the following cases of infections due to fosfomycin sensitive strains such as Pseudomonas Aeruginosa, Proteus Vulgaris, Serratia Marcescens and Staphylococus aureus and Escherichia COLI anti -antibacterial: Bronchitis, bronchitis, bacterial bronchiectasis, pneumonia, purulent lung disease, pleural pleurisy, peritonitis, nephritis - pyelonephritis, cystitis, auxiliary inflammation, bacterial infections in the uterus, pelvic cavity infection, uterine murder inflammation and bartholin gland inflammation.

Pharmacological

No data.

pharmacokinetics

No data.

Before taking Fosmicin for I.V Use injection drugs for infections (10 vials)

How to use

Fosmicin for I.V Use powdered powder.

Dosage

intravenous dripping:

The usual daily dose fosfomycin uses intravenously 2 - 4g (content); Intravenous transmission in a drip transmission. The above dose is divided 2 times. Each dose is dissolved at 100 - 500ml of infusion, the transmission time is from 1-2 hours.

intravenous injection:

The daily dose is also equal to intravenous dripping dose but must be divided into 2-4 times. The solvent used to dissolve 1 - 2g of this preparation is 20ml of injection water, according to Japanese pharmacopoeia or 20ml of 5%glucose solution, according to Japanese pharmacopoeia. Intravenous time must be done in 5 minutes or more.

The aforementioned dose can be adjusted according to the age of patients and the symptoms of severe, mild disease.

Children over 12 years: Intravenous injection shall not exceed 100 - 200mg/kg/day

Average renal failure (Creatinine clearance ≥ 60 ml/minute): No need to adjust the dose and distance between drug use.

Patients with creatinine clearance below 60 ml/minute: It is necessary to extend the distance between drug use. The distance between the drug use depends on the clearine clearance.

Creatinine clearance (ml/min) The distance between 2 times using fosfomycin (hour)

40 - 60 12 30 - 40 30 36

Elderly: No dose adjustment.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when using overdose?

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Fosmicin for I.V use drugs often have unwanted effects (ADR) such as:

Monitoring results on the safety of the drug in the years after the preparation was circulated on the market were presented below. Received clinical reports of 33,711 cases provided by the physician from 2618 medical facilities nationwide. In 710 side effects occurring in 591 patients (1.75%), the main side effects occur as follows:

Side effects

The number of patients

liver/bile (increase SGOT, SGPT ...) 378

jute ...) 88 (Pain, blush) 15 `` 7 Endocoubid leukemia (leukopenia ...) 7

Shock: Need to monitor patients carefully because there may be shock (frequency Heavy colitis with bloody stools such as fake colitis ( Objective hemorrhage and granular leukemia (

Other side effects:

Monitor patients carefully, stop using the product and take appropriate treatment if the abnormal phenomenon occurs.

Prize ... gastrointestinal tract Dowers stomatitis, nausea, vomiting, abdominal pain, loss of appetite ... ho, asthma ... Headache, thirst, fever, discomfort, chest pain, chest feeling heavy, nervous ...

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Fosmicin for I.V use contraindicated in the following cases:

Patients with a history of hypersensitivity to fosfomycin.

Caution when using

According to the general principle, the time to use this drug should be limited to the minimum time limit as required by the treatment method for each patient, after determining the sensitivity of bacteria to the drug, to avoid the resistance of bacteria.

Be cautious when used for patients:

Patients or family members have congenital allergies such as asthma, rash, urticaria.

Important note:

Patients should be carefully monitored to prevent the risk of shock.

Elderly:

This product is excreted mainly through the kidneys. The side effects may occur for the elderly because their kidney function has often decreased. Be careful when taking this medication for elderly patients, need to reduce the amount of sodium put into the body due to heart failure, kidney failure, high blood pressure ...

Children:

The safety of the drug for premature and infant babies has not been determined. Do not take medicine for children under 12 years old.

Be cautious when using:

Sugar used: Only use this product by intravenous line. Moreover, in any case possible, this preparation should be used by transmitting dripping into veins. Therefore, it is necessary to pay attention to the injection site, techniques applied in treatment, the speed of fluid transmission as slowly as possible.

Use drugs for women during pregnancy and lactation

Because the safety of this preparation for pregnant women has not been determined, recommended not to use this drug for pregnant or suspected pregnant women. Recommended to avoid using this product when breastfeeding. If the treatment of this product is necessary, it is necessary to stop breastfeeding during treatment.

The effect of the drug on the ability to drive and operate machinery

Caution when driving and operating machinery because the drug can cause headaches, tinnitus, dizziness, discomfort ...

Drug interaction

metoclopramide and drugs that increase the gastrointestinal motility when used simultaneously with fosfomycin will reduce fosfomycin levels in plasma and urine.

fosfomycin has an increase in the same effect as P-Lactam antibiotics, aminoglycoside, macrolide, tetracycline, chloramphenicol, rifamycin, colistin, vancomycin and lincycin.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

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