Fosmicin-S for Otic Meiji 300mg medicine for external ear infections, otitis media (10ml)

Dosage form Bottle
Specifications Fosfomycin sodium

Ingredient

Composition information	Content
Fosfomycin sodium	300mg

Uses

indications

Fosmicin-S for otic drugs are indicated in the following cases:

Treatment of external otitis, otitis media between bacteria sensitive to fosfomycin: Staphylococus sp., Proteus sp., Pseudomonas aeruginosa.

Pharmacokology

fosfomycin is an antibiotic derived from fosfonic acid, extracted from streptomyces fradiae and other streptomyces or synthesized, have bactericidal effects. The bactericidal effect of the drug is due to the inhibition of enolpyruvyl transferase enzyme, reducing the formation of diphosphate-n-acetylmuramic acid, which is the first stage of the formation of bacterial cells.

fosfomycin has a broad spectrum. In vitro is effective on gram -positive and gram -negative bacteria, especially bacteria that often cause urinary tract infections such as E. coli, proteus, klebsiella, enterobacter, pseudomonas, Serratia, Enterococcus, Staphylococcus sensitive or meticilin, streptococcus pneumonia, Haemophilus, Haemophilus In ﬂ uenzae and Neisseria spp. However, in reality there are several pseudomonas aeruginosa strains resistant to drugs and bacteroides are not sensitive. In vivo effectively has been determined for E. Coli and Enterococcus Faecalis.

In addition to urinary tract infections and digestion, fosfomycin has been used by many countries around the world or in combination with other antibiotics to treat results (81.1%) of gram -positive bacteria infection and/or grams including pneumonia and other respiratory infections, myelitis, meningitis, ear, nose and throat, foreign bacteria, bacteria, bacteria Road.

pharmacokinetics

There is no information.

Before taking Fosmicin-S for Otic Meiji 300mg medicine for external ear infections, otitis media (10ml)

How to use

How to mix

Step 1: Use the index finger to remove the belt in the lid of the powder.

Step 2: Hold the dough with the left hand and pull the belt of the vial down to the side.

Step 3: Remove the lid by pulling to the right.

Step 4: After removing the lid, continue removing the aluminum lid and the rubber button above.

Step 5: Remove the large lid of the distilled water jar and install the tip of the distilled water jar into the dough bottle until you hear the "click". Shake well for completely dissolved powder.

Step 6: Pour the drug solution into a distilled water bottle. Remove the jar of the powder and tighten the drug bottle with a large lid.

How to small medicine

lies towards painless ears, pain upwards. Avoid letting the tip of the bottle contact into the ear. Maintain this location for about 10 minutes. Put 10 drops of drug solution (about 0.5 ml) into the ear pain 2 times/day in the morning and evening. Small number of adjustments depending on symptoms, can increase up to 4 times/day. After small ears, keep the position in 10 minutes.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when overdose? There are currently no specific fosfomycin antagonists, so when poisoning, it is necessary to apply active treatment, symptomatic treatment and fosfomycin from the body.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Fosmicin-S for OTIC, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Skin: rash.

ears: hearing disorders.

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Fosmicin-S for otic drugs contraindicated patients with a history of hypersensitivity to any component of the drug.

Be cautious when using

only use drugs to shrink ears. Do not use drugs to shrink eyes.

Feeling dizziness, dizziness can occur when small drugs in the ear. Therefore, drugs should be kept at body temperature as long as possible.

After dissolving the drug: Do not use the drug when left at room temperature for 2 weeks or longer after the drug has been re -completed.

In treatment, if not combined with antibiotics may experience fast -resistant bacteria due to mutations. To limit bacterial fosfomycin resistance, it is necessary to coordinate with other antibiotics.

1 g Fosfomycin Dinatri contains about 0.33 g of sodium, so be careful when taking drugs in people with edema, hypertension or corticosteroids. People with heart failure are taking Digitalis type aid if they use prolonged fosfomycin need to regularly check potassium potassium and use potassium supplements because the drug can lower potassium potassium.

The ability to drive and operate machinery

Caution when driving and operating machinery because the drug can cause headaches, tinnitus, dizziness, discomfort.

Pregnancy

There is no information. Therefore, the use of fosfomycin in pregnant women must be very careful and only use when really necessary.

Breastfeeding period

Medicine into breast milk. Although fosfomycin concentration is very low in breast milk, it should not be taken when the mother is breastfeeding. In case of using fosfomycin, the mother must stop breastfeeding.

Drug interaction

metoclopramid and drugs that increase the gastrointestinal motility when used simultaneously with fosfomycin will reduce fosfomycin levels in plasma and urine.

fosfomycin has an increase in the same effect as β-lactam antibiotics, aminoglycosides, macrolid, tetracyclin, chloramphenicol, rifamycin, colistin, vancomycin and lincycin.

Storage

Store to avoid light, temperatures below 300C and only use within 14 days.

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