Fugacar Janssen Fruit Fruit Fruit Treated Infection A or MOTS

Dosage form Chewing tablet
Specifications 1 tablet box
Ingredient Mebendazole

Ingredient

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Composition information	Content
Mebendazole	500mg

Uses

Indications

Fugacar indicated in the treatment of one or more gastrointestinal worms: Enterobius vermicularis (needle worm), trichuris trichiura (hairworm), Ascaris lumbricoides (roundworm), Ancylostoma Doodenale, Necator Americanus (Necator Americanus (Necator Americanus (Necator Americanus (Necator Americanus (Necator American hook).

Pharmacokological

Mebendazole operates on the spot in the intestinal tract by hindering the formation of cell tubes in worms. Mebendazole binds specific to the micro tube and causes superstitious degenerative changes in worms. Therefore, leading to disorders of glucose absorption and digestive function of worms causing self -resolution process.

pharmacokinetic

absorption

After oral use,

Distribution

Mebendazol's cohesion of plasma proteins is about 90 to 95%. The distribution of 1 to 2 l/kg shows that Mebendazole can penetrate the non -circuit organization. This is proved by data on tissue concentration in patients with chronic treatment with Mebendazol (for example, a dose of 40 mg/kg/day for 3 to 21 months).

Metabolism

Mebendazol is used by oral is metabolized mainly by the liver. The plasma concentration of the main metabolites (amino and amino hydroxylation of Mebendazol) is much higher than that of Mebendazol. The impaired liver function, poor metabolism or decline in biliary exhaust may lead to higher plasma mebendazol levels.

Elimination

Mebendazol, the types of links of Mebendazol and its metabolites can undergo many rounds of intestinal circulation and are eliminated through urine and bile. The sale time after a dose is about 3 to 6 hours in most patients.

Stable pharmacokinetic status: Mebendazol's concentration and main metabolites in plasma increases when used for a long time (for example, a dose of 40 mg/kg/day for 3 to 21 months), leading to concentration at a stable state 3 times higher than the single dose.

Before taking Fugacar Janssen Fruit Fruit Fruit Treated Infection A or MOTS

How to use

No need to apply special ways such as diet or laxative.

Dosage

1 single fugacar 500 mg.

Children: Take 1 single dose of fugacar 500 mg.

Children

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? Except for the case of granulocytosis and nephritis-sphere, these harmful reactions are also recorded in patients treated with the standard doser of Mebendazole.

Symptoms: abdominal spasms, nausea, vomiting and diarrhea.

Treatment: There is no specific antidote. Can use activated carbon if appropriate.

What to do when forgetting a dose?

Side Effects

When using Fugacar deworming, you may experience unwanted effects (ADR).

Common, ADR> 1/100

No report.

Uncommon, 1/1000

No report.

Rare, ADR

Blood and lymphatic system: neutral leukopenia. Stevens-Johnson syndrome, foreign rash, angioedema, urticaria, hair loss.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Fugacar Contraindicated in the following cases:

Children under 1 year of age in the treatment of a series of cases of one or more types of worms.

Hypersensitivity to drugs or excipients of the drug.

Be cautious when using

Be cautious when using fugacar enemies for children under 2 years old.

In after -sales monitoring, seizures in children including children under 1 year of age are reported with very rare frequency.

Fugacar has not been widely studied in children under 2 years old. Therefore, Fugacar should only be used for children from 1-2 years if the benefits are greater than the potential risk (for example, if the child's worm infection is significantly affected by the child's nutrition and physical development).

To reduce the risk of choking, it is advisable to consider using fugacar in the form of oral fluid for patients such as children who cannot swallow the tablet form.

Rarely reports on liver dysfunction can recover, hepatitis and neutropenia in patients treated with Mebendazol at standard doses in indicated diseases. These events, along with nephritis - platelets are also reported when using the dose higher than the recommended and treated dose levels in a long time.

Results from a disease study, research on the appearance of Stevens-Johnson syndrome/poisoning epidermal necrosis (SJS/Ten) suggesting the ability to have the relationship between SJS/Ten and simultaneous use of Mebendazol and Metronidazol. There is no additional data on drug -drug interaction. Therefore, avoid simultaneous use of Mebendazol and Metronidazol.

The ability to drive and operate machinery

Fugacar 500 mg does not affect alertness and driving ability.

Pregnancy

Mebendazole shows signs of toxicity and teratogenicity in rats and rats, no harm to the reproduction of other experimental animals. The risk should be considered and the desired treatment benefits when prescribing Fugacar 500 mg for pregnant women, especially in the first 3 months of pregnancy.

Breastfeeding period

It is not known whether Mebendazol is excreted through breast milk. Therefore, be careful when using Fugacar 500 mg for breastfeeding women.

Medicinal interaction

used at the same time with cimetidine can inhibit the metabolism of Mebendazol in the liver, the result increases the concentration of drugs in plasma, especially in the case of prolonged treatment.

Should avoid simultaneous use of Mebendazol with metronidazol.

Storage

Store at a temperature of 15 ° C - 30 ° C.

To be out of reach of children.

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