Fugacar Janssen medicine treats one or more intestinal worms (1 blister x 4 tablets)

Dosage form Box of 1 blister x 4 tablets
Specifications Mebendazole

Ingredient

Composition information	Content
Mebendazole	500mg

Uses

indicated

Fugacar box of 4 treatment tablets in case of one or more intestinal worms such as enterobius vermicularis (needle worm); Trichuris Trichiura (hairworm); Ascaris Lumbricoides (roundworm); Ancylostoma duodenale, Necator Americanus (hookworm).

Pharmacokology

Mechanism of operation:

In the indications for treatment, Mebendazol operates on the spot in the intestinal tract by hindering the formation of cellular microcks in the worms. Mebendazole binds specific to the micro tube and causes superstitious degenerative changes in worms. Therefore, leading to disorders of glucose absorption and digestive function of worms causing self -resolution process.

pharmacokinetics

absorption:

After oral use, Distribution:

Mebendazol's cohesion of plasma proteins is about 90 to 95%. The distribution of 1 to 2 l/kg shows that Mebendazole can penetrate the non -circuit organization. This is shown by the data about tissue concentration in patients with chronic treatment with Mebendazol (for example, a dose of 40 mg/kg/day for 3-21 months).

Metabolism:

Mebendazol is used by oral is metabolized mainly by the liver. The plasma concentration of the main metabolites (amino and amino hydroxylation of Mebendazol) is much higher than that of Mebendazol. The impaired liver function, poor metabolism or decline in biliary exhaust can lead to higher plasma mebendazol levels.

Era:

Mebendazol, the types of links of Mebendazol and its metabolites can undergo many rounds of intestinal circulation and are eliminated through urine and bile. The sale time after a dose is about 3 to 6 hours in most patients.

Before taking Fugacar Janssen medicine treats one or more intestinal worms (1 blister x 4 tablets)

How to use

No need to apply special ways such as dieting or laxatives.

Dosage

Adults and children over 2 years:

Take 1 single fugacar 500 mg.

Children

Due to the risk of convulsions should be contraindicated to use fugacar 500 mg for children under 1 year of age in the treatment of a series of cases of one or more types of worms.

Fugacar 500 mg has not been widely studied in children under 2 years old. So only use Fugacar 500 mg for children aged 1-2 years if the benefits are greater than possible.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do you do when overdose?

Except for the case of granulocytosis and nephritis-sphere, these adverse reactions are also notified in patients treated with Mebendazol at the standard dose.

In accidentally taking overdose, abdominal spasms, nausea, vomiting and diarrhea may be encountered.

How to handle: There is no specific antidote. Can use activated carbon if appropriate.

What to do when you forget 1 dose?

Side Effects

Uncommon, 1/1000

Digestive system: abdominal discomfort, diarrhea, flatulence.

Skin and subcutaneous tissue: rash.

Rare, ADR

Blood and lymphatic system: neutropenia.

The immune system: Hypersensitivity includes anaphylactic reaction and anaphylactic reaction.

Nervous system: convulsions, dizziness.

Digestive system: abdominal pain.

Hepatitis system: Hepatitis, abnormalities for liver function tests.

Skin and subcutaneous tissue: Poisoned epidermal necrosis, Stevens-Johnson syndrome, foreign rash, angioedema, urticaria, hair loss.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Contraindicated

Fugacar medicine box 4 tablets Contraindications in the following cases:

Children under 1 year of age in the treatment of a series of cases of one or more worms infection.

Hypersensitivity to drugs or excipients of the drug.

First 3 months of pregnancy.

Patients with liver failure.

Be cautious when using

Precautions when used for children under 2 years old.

In after -sales monitoring, seizures in children including children under 1 year of age are reported with very rare frequency.

To reduce the risk of choking, it is recommended to consider using 500 mg Fugacar in the form of oral fluid for patients such as children who cannot swallow the tablet form.

Rarely reports on liver dysfunction can recover, hepatitis and neutropenia in patients treated with Mebendazol at standard doses in indicated diseases. These events, along with nephritis, are also reported when using the dose higher than the recommended and treated dose in a long time.

Results from a case-Control Study study research on the appearance of Stevens-Johnson syndrome/poisoned epidermal necrosis (SJS/Ten) suggesting the possibility of SJS/Ten and simultaneous use of mebendazol and metronidazol. There is no additional data on drug-drug interactions. Therefore, avoid simultaneous use of Mebendazol and Metronidazol.

The ability to drive and operate machinery

Fugacar box 4 tablets does not affect alertness and the ability to drive.

Pregnancy

Mebendazole shows signs of fetal toxicity and monster in rats and mice. There is no harmful effect on the reproduction of other experimental animals.

Should consider the risk and the desired treatment benefits when prescribing Fugacar 500 mg for pregnant women, especially in the first 3 months of pregnancy.

The period of breastfeeding. Therefore, be careful when using Fugacar 500 mg for nursing women.

Drug interaction

used at the same time with cimetidine can inhibit the metabolism of Mebendazol in the liver, the result increases the concentration of drugs in plasma, especially in the case of prolonged treatment.

Storage

Storage at temperatures 15 ° C - 30 ° C.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.