Furmet Cream Medisun helps to treat skin infections (10g)

Dosage form Box
Specifications Clotrimazole, Betamethasone, Gentamicin Sulfat

Ingredient

Composition information	Content
Clotrimazole	100mg
Betamethasone	6.4mg
Gentamicin Sulfat	10mg

Uses

Indications

Reduce inflammation of skin diseases to respond to corticosteroids and show signs of secondary infections caused by bacteria sensitive to the components of the drug or when suspected is likely to be infected.

Disorders include: inguinal dermatitis, chronic dermatitis in the limbs, folding dermatitis, foreskin inflammation, shingles, seborrheic dermatitis due to eczema , contact dermatitis, folliculitis, disc nails, anal itching, skin rash, seborrheic skin, pustom Foot, fungal skin thighs and body fungus.

Pharmacokology

Gentamicin Sulfate is an antibiotic belonging to the aminoglycoside group that has bactericidal effects through inhibiting bacterial biosynthesis of bacteria. The actual gentamicin antibacterial spectrum includes Gram -negative aerobic bacteria and staphylococcus aureus, including strains that produce penicillinase and methicillin resistance. Gentamicin has little effect on gonorrhea, streptococcal, steering cells, meningococcal brain, citrobacter, Providencia and Enterococci. Mandatory anaerobic bacteria such as bacteroides, clostridia are all resistant to Gentamicin.

betamethasone is a synthetic corticosteroid, which has a very strong glucocorticoid effect, accompanied by negligible mineralocorticoid effects. 0.75 mg of betamethasone has an anti -inflammatory effect equivalent to about 5 mg of prednisolon. Betamethasone has anti -inflammatory, anti -rheumatic and anti -allergic effects. Drugs used oral, injected, injected, inhaled or applied to treat many diseases that need to be indicated to use corticosteroids, except for adrenal insufficient states, prefer hydrocortison and supplementing Fudrocortison. Due to less mineralocorticoid effect, Betamethasone is very suitable in cases where the pathology that holds water is disadvantage. High doses, betamethasone has immunosuppressive effects.

Clotrimazole is a broad -spectrum antivirus drug used to treat skin diseases due to various species that cause diseases and also work on trichomonas, staphylococcus and bacteroides. There is no effect on lactobacilli. The mechanism of acting of clotrimazole is to link with phospholipids in the fungal cell membrane, changing the permeability of the membrane, causing loss of intracellular essential substances leading to the destruction of fungal cells. Invitro, Clotrimazole have the effect of restraining and killing fungi, depending on the concentration, with Trichophyton rubrum, Trichophyton Cosum, Microprum Canis and Candida species.

pharmacokinetics

absorption:

Gentamicin is not absorbed through the gastrointestinal tract. Gentamicin is used intravenously or intramuscularly.

betamethasone is easily absorbed through the gastrointestinal tract. The drug is also easily absorbed when used on the spot. When applied, especially if the skin is torn or when the skin is torn or when the rectal indentation, there may be a amount of betamethasone that is absorbed enough for the whole body effect.

Clotrimazole is applied on the skin or vaginal, Clotrimazol is very few absorbed.

Distribution:

Gentamicin is less attached to plasma proteins, diffuses mainly on extracellular fluids and diffuses easily into the inner ear foreign.

betamethasone quickly distributed into all tissues in the body. The drug through the placenta and can be exported to breast milk in small amounts. During the circulation, Betamethasone is widely linked to plasma proteins, mainly with globulin and the albumin is less.

Metabolism:

Gentamicin is not metabolized and eliminated (almost unchanged) into the filtered urine in the glomerular filter.

Metabolism of synthetic corticosteroids, including betamethasone, slower and their protein bonding force is lower, which can be explained stronger than natural corticosteroids.

Era:

Gentamicin has at least 70% of the dosage output output for 24 hours.

Before taking Furmet Cream Medisun helps to treat skin infections (10g)

How to use

Apply the drug to the sick and surrounding skin 2-3 times a day.

For the treatment to have regular results.

Dosage

The treatment time depends on the level, position of the sick skin and the response of the patient. However, if there is no clinical improvement after four weeks of applying the drug should review the diagnosis; Especially for children not exceeding 2 weeks, babies do not exceed 1 week.

What to do when overdose?

Patients need to stop using the drug.

What to do when you forget 1 dose?

There is no information.

Side Effects

When using Furmet, you may experience unwanted effects (ADR).

Local reactions (> 1 %) include mild burns, irritation, allergic dermatitis due to contact, burning pain in the skin or vagina.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

contraindicated drugs in the following cases:

Patients with hypersensitivity to any component of the drug. Other.

Be cautious when using

should not use a wide area or take medicine for a long time.

Do not take the drug in the form of pressing.

Do not use clotrimazole for the treatment of systemic fungal infections.

Must treat the drug enough time despite symptoms. After 4 weeks of treatment, if not supported again. Inform the physician if there is a sign of increased irritation in the topical area (red, itching, burns, blisters, swelling), signs of hypersensitivity.

The ability to drive and operate machinery

The drug does not cause drowsiness, so it can be used for people who are driving and operating machinery.

Pregnancy

Safety when using corticosteroids during pregnancy has not been clearly studied. It is important to consider when using the drug during pregnancy if the benefits bring greater than the potential risk to the fetus. The drug should not be used in large quantities and long time for pregnant women.

The period of breastfeeding

The ability to enter breast milk, should stop breastfeeding when using the drug.

Drug interaction

There has been no notice of the effect of copper or antagonism between clotrimazole and nystatin, amphotericin B or flucytosin with C. albicans.

Tacrolimus concentration in the serum of people with liver transplant increases when used simultaneously with clotrimazole. Therefore, Tacrolimus dose should be reduced according to demand.

Storage

Store in a dry place, avoid light and humidity, temperatures below 30 ºC.

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