Furosemide Stada 40mg medicine for edema, hypertension (5 blisters x 10 tablets)

Dosage form Box of 5 blisters x 10 tablets
Specifications Furosemid

Ingredient

Composition information	Content
Furosemid	40mg

Uses

Indications

Acute pulmonary edema treatment; Flemes due to heart, liver, kidneys and other edema.

Treatment of hypertension when kidney damage.

Treatment of hypercalcemia. The drug acts on the upward branch of the Henle straps, so it is classified as a group of diuretics.

The main mechanism of action of Furosemid is to inhibit the Na+, K2+, 2CI- transportation system in the thick section of the branch on the Henle straps, increasing the excretion of these electrolytes accompanied by increased water export exercises. There is also an increase in the elimination of Ca2+ and Mg2+. The diuretic effect of the drug is strong, thus leading to hypotension, but often weak. In patients with pulmonary edema, Furosemid causes increased venous volume, thus reducing the money burden for left ventricle before seeing the diuretic effect.

pharmacokinetic

absorption

Furosemid is well absorbed by oral, diuretic effects appear quickly after ½ hours, reaches the maximum concentration after 1-2 hours and maintains the effect from 4-6 hours. Anti -hypertension effect is longer. For people with severe edema, the bioavailability of the drug is reduced, possibly due to the direct effect of reducing the absorption of the digestive tract. Furosemid's absorption can be extended and can be reduced by food.

Distribution

Furosemid passes through the placenta and into breast milk.

Metabolism

No report.

Elimination

A third of the absorption drug is excreted through the kidneys, the rest is excreted through the urine, mainly in the form of non -metabolic, completely eliminated drugs for 24 hours.

Before taking Furosemide Stada 40mg medicine for edema, hypertension (5 blisters x 10 tablets)

How to use

Furosemide STADA 40 mg is used by oral.

Dosage

edema:

The oral dose started is usually 40mg/day. Adjust the dose if necessary depending on the response.

Mild cases may be used 20mg/day or 40mg daily.

Some cases may increase the dose to 80mg or more, divided into 1 or 2 times a day.

Severe cases, the dose may be increased to 600mg/day. For children with oral doses are 1 - 3mg/kg/day, up to 40mg/day.

Hypertension:

Furosemid is not the main drug to treat hypertension and can be coordinated with other anti -hypertension drugs to treat hypertension in people with kidney damage.

Oral dose is 40 - 80mg/day, lone or in combination with other antihypertensive drugs.

Hypercalcemia:

dose of 120mg/day orally or divided into 2 or 3 small doses.

Elderly: may be more sensitive to the effect of the drug than the dose commonly used in adults.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Symptoms

Water and electrolyte imbalance include: headache, muscle weakness, cramps, thirst, hypotension, anorexia, fast pulse.

Treatment

Compensate for the amount of water and electrolytes lost.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

Common, ADR> 1/100

Circulation: Reducing blood volume in case of high doses, hypotension.

Metabolic: Hypotension, hypoglycema, hypoxemia, blood calcium, hyperiemia, hyperuricemia, alkaline infection due to hypoglycemia.

Uncommon, 1/1000

Digestive: Nausea, vomiting, digestive disorders.

Rare, ADR

Blood: leukopenia, thrombocytopenia, loss of granulocytes.

skin: skin, vasculitis, paresthesia.

Metabolic: hyperlemia, urinary glucose.

ears: tinnitus, recovery hearing (at high doses).

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Contraindicated

Furosemide Stada 40mg contraindications in the following cases:

Hypersensitivity to Furosemid and with sulfonamid derivatives, such as diabetes sulfamid.

The situation of liver coma, liver coma.

Animal or renal failure due to toxic drugs to the kidneys or liver.

Caution when using

Caution for patients with prostate hypertrophy or difficult urination because it can promote urinary retention.

The ability to drive and operate machinery

Recommended patients cautious when driving, operating machinery because the drug can cause hypotension, headache.

Pregnancy

Thiazid, thiazid diuretics and diuretics straps evenly through the fetal fence into the fetus and causing water disorders and electrolytes for the fetus.

With thiazid and many cases of platelet reduction in infants have been informed. This risk also appears after the use of diuretics such as Furosemid and Bumetamid. Therefore, in the last 3 months of pregnancy, the drug is only used when there is no alternative medicine, and only at the lowest doses in a short time.

Breastfeeding period

using Furosemid during breastfeeding is at risk of inhibiting milk secretion. This case should stop breastfeeding.

Medicinal interaction

Medicinal interaction may occur when using Furosemid in combination with the following drugs:

cephalothin, cephaloridin: Increased kidney toxicity.

Lithi salt: Increased blood lithium concentration, which can be toxic. Should avoid using if you cannot monitor the blood lithium tight.

aminoglycozide: Increased toxicity for ears and kidneys. Should avoid use at the same time.

heart glycozide: Increased toxicity due to hypoglycemia. Need to monitor blood potassium and electrocardiograms.

Steroid anti -inflammatory drugs: Reduce diuretic effects.

corticosteroid: Increased k+discharge.

Medications for diabetes treatment: The risk of increased blood glucose. Need to monitor and adjust the dose.

Non -reducing muscle relaxants: Increased muscle relaxation effect.

anticoagulant: Increased anticoagulant effect.

cisplatin: Increased hearing toxicity. Should avoid use at the same time.

Hemotrogate drugs: Increased hypotension effect. If coordinated, the dose should be adjusted. Especially when combined with Angiotensin transfer enzyme inhibitors, blood pressure may be severe.

Storage

Temperature does not exceed 30 ° C.

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