Gabahasan 300 Hasan Medicines supported in local epilepsy, peripheral neuritis pain (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Gabapentin

Ingredient

Composition informationContent
Gabapentin300mg

Uses

Indications

Gabapentin drugs are indicated in the following cases:

  • Support treatment in local epilepsy. The chemical structure of Gabapentin is similar to neurotransmitter inhibitors, gamma-aminobutyric acid (GABA), but Gabapentin does not directly affect GABA receptors, does not change the structure, release, transformation and GABA recovery.

    pharmacokinetic

    absorption:

    Gabapentin absorbed through the gastrointestinal tract under saturated mechanism (when the dose increases, bioavailability decreases). The drug reaches the peak concentration in plasma after drinking 2 hours and reaches a stable concentration after 1-2 days. The effective serum concentration of the drug has not been determined.

    Gabapentin plasma concentrations range from 2mg/liter (2 micrograms/ml) to 20mg/liter (20 micrograms/ml). Born is about 60% when used at a dose of 1.8g/24 hours and does not correspond to the dose, if the dose increases over 1.8 g/24 hours, the bioavailability decreases. Birth is about 35% when used at a dose of 4.8 g/24 hours. Food less affecting the speed and level of absorption.

    Distribution:

    gabapentin is distributed throughout the body, entering breast milk, linking with very low plasma proteins (

    Metabolism:

    gabapentin is almost no metabolism in the body.

    Era:

    Elimination mainly through the kidneys in constant form. Gabapentin's waste time is about 5 to 7 hours in people with normal kidney function, in elderly patients and people with impaired renal function, plasma galapentin clearance. Gabapentin may be excluded from plasma with hemolysis, which should be adjusted in these patients.

    • Before taking Gabahasan 300 Hasan Medicines supported in local epilepsy, peripheral neuritis pain (3 blisters x 10 tablets)

    How to use

    Oral drugs.

    Dosage

    anti -epileptic:

    Adults and children over 12 years:

  • The first day: 300mg x 1 time.
  • Monday: 300mg/time x 2 times. Maximum no more than 2400mg/day.

    Should divide the total daily dose for each drug and the medication distance should not exceed 12 hours. When using high doses can be divided 4 times/day.

    For patients with impaired renal function and hemolysis must reduce the dose, appropriate dose to be adjusted according to creatinine clearance, recommended as follows:

    Creatinine clearance (ml/minute)
    Dosage
    The time

    15 - 29 300mg/day, divided 3 times (*)

    Children from 6 to 12 years old:

  • The first day: 10mg/kg/day, divided 3 times.
  • Monday: 20mg/kg/day, divided 3 times. time.

    • 3 -year -old children to under 6 years old:

    The starting dose of 10 - 15mg/kg/day, divided 3 times; Increase the dose in 3 days to get a dose of 25 - 30mg/kg/day for children 3-4 years old.

    For children 5 - 6 years old, the dose is 25 - 30mg/day, the total dose/day is divided into 3 times.

    There is no evaluation of the use of gabapentin for children under 12 years old with renal function.

    Treatment of pain due to peripheral nerves, shingles after shingles:

    Adults:

    Take no more than 1800mg/day, divide 3 times or use as follows:

  • The first day: 300mg/time.
  • Monday: 300mg/time x 2 times/day.

    Elderly:

    Dosage may be low due to poor kidney function.

    Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. To get the right dose, you need to consult a doctor or medical expert

    What to do when overdose? Most cases of overdose recover after using supportive treatment. There may be drugs from the body by hemolysis.

    In case of emergency or overdose, immediately call the 115 emergency center or visit the nearest local health station.

    In addition, you need to record and bring the list of drugs you have used, including prescription and non -prescription drugs.

    What to do when you forget the dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

    • Side Effects

    When using Gabahasan 300, you may experience unwanted effects (ADR).

    Often mild or medium side effects and tend to decrease within 2 weeks when continuing treatment.

    Common

    Mobilizing loss of coordination, vibrating eyeball, fatigue, dizziness, edema, drowsiness, memory loss; Children from 3 to 12 years of age have nerve problems such as anxiety, change of behavior (fussing, refreshing or depression, too excited, anti -opposition attitude ...); indigestion, dry mouth, constipation, abdominal pain, diarrhea; Foreign edges; rhinitis, sore throat, cough, pneumonia; dizziness, vision loss; joint pain, muscle pain; rashes, skin rash, leukopenia; impotence, virus infection.

    Less:

    Memory loss, loss of language, depression, irritability or mental changes, temperament, mild paralysis, decrease or loss of sex, headache; Gastrointestinal disorders, bleeding, stomatitis, loss or taste disorders; Hypotension, angina, peripheral disorders, suspense, weight gain, liver enlargement.

    Rare:

    Neurological paralysis, personality disorders, increased sensitivity, reduced motor function, mental disorders; Stomach - duodenal ulcer, esophagitis, colitis, rectal inflammation; cough, hoarseness, respiratory mucosa, decreased pulmonary ventilation, pulmonary edema; Itching eyes, watery eyes, retinopathy, iritis; Inflammation of cartilage, osteoporosis, back pain; leukopenia (usually asymptomatic), prolonged bleeding time; fever or cold; Stevens-Johnson syndrome.

    Instructions on how to handle ADR

    Notify the doctor the side effects when taking the drug.

    Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    Contraindicated

    Gabahasan 300 mg contraindicated in the following cases:

  • Hypersensitivity to Gabapentin or any ingredients of the drug.

    • Precautions when using

    Warning

    Use cautiously for people with a history of mental disorders, people with impaired kidney function and hemolysis.

  • The drug can cause false positive when testing proteinuria.

    The ability to drive and operate machinery

    gabapentin can cause dizziness, fatigue, drowsiness, dizziness, vision loss ... Therefore, be careful to use drugs when operating train, machinery.

    Pregnancy and lactation

    only use drugs for pregnant and lactating women when they are really necessary and consider higher benefits than risk risks.

    Drug interaction

    When used simultaneously, Gabapentin does not change the pharmacokinetics of commonly used anti -epilepsy drugs such as Carbamazepin, Phenytoin, Valproic Acid, Phenobarbital, Diazepam.

    Anti -acid drugs reduce the bioavailability of gabapentin by about 20% due to the impact on the absorption of the drug. Gabapentin must be used after at least 2 hours of antacids.

    • Storage

    Store drugs at less than 30 ° C, leave a cool dry place, avoid direct light, moisture prevention.

    Do not store drugs in the bathroom, in the freezer. Each drug may have different storage methods. Please read the instructions on the packaging carefully or ask the doctor.

    Do not let the product in children can be with.

    Notice the appearance of the product, if the product shell shows signs of openness, the product is discolored, watery or deformed, then do not use the product. If you want to destroy it, you will not be thrown on the sewer, the toilet ... Instead, you should consult a doctor and pharmacist to destroy the drug safely, without causing environmental pollution.

    Expiry date: 48 months from the date of manufacture.

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