Gastsus BV Pharma oral discharge reduced symptoms of indigestion, heartburn, digestive ulcers, gastritis (30 packs)

Dosage form 30 package box
Specifications Magnesi hydroxid, oxetacain, aluminum hydroxyd

Ingredient

Thành phần cho 10ml

Composition information	Content
Magnesi Hydroxid	196mg
Oxetacaine	20mg
Aluminum hydroxyd	582mg

Uses

Indications

Gastsus BV Pharma is indicated in the following cases:

Reduce symptoms in cases of indigestion, heartburn, abdominal pain related to gastrointestinal ulcers, gastritis, esophagitis. place.

Gastsus is a combination of two antacid agents including aluminum hydroxyd and magnesi hydroxyd, which neutralizes gastric acid secreted from the cells of the stomach and thereby protects the stomach lining and reduces pain due to ulcers.

Magnesi Hydroxyd has a quick effect while aluminum hydroxyd has a slow effect, a harmonious combination of these two substances makes the product starting to work quickly and extend the time.

aluminum hydroxyd is a astringent and can cause constipation, this side effect is also balanced by Magnesi Hydroxyd which can cause diarrhea.

In addition, the product also adds oxetacaine (or oxethazain) is a numbness in the spot of the amids with long effects, numb the gastric wall mucosa to reduce symptoms of pain -related pain related to stomach and gastrointestinal pain.

pharmacokinetics

magnesium hydroxid reacts with hydrochloric acid in the stomach to form magnesi chloride salt. This small amount of salt can be absorbed and excreted in urine or excreted in feces.

aluminum hydroxid reacts with hydrochloric acid in the stomach to form aluminum chloride. A small amount is absorbed and eliminated through urine. Most aluminum is still in the stomach - intestines and forms very few aluminum salts that are absorbed, including hydroxid, phosphate, carbonate and fatty acid derivatives, excreted in feces.

oxetacain

After taking 10ml of drugs containing 20mg of oxetacaine, the peak of the plasma of oxetacaine is reached after 1 hour of about 20ng/ml. This substance is quickly metabolized, the sale time is about an hour. Under 1% of Oxetacaine is detected in urine in a constant form in 24 hours. The metabolites are mainly beta-hydroxy mephentin and beta-hydroxy phentermin. Mephentine and Phentermin accumulated with a significant amount of plasma in 24 hours and excreted through urine below 1% of the dose.

Before taking Gastsus BV Pharma oral discharge reduced symptoms of indigestion, heartburn, digestive ulcers, gastritis (30 packs)

How to use

take 15 minutes before meals and at bedtime. Drinking non -diluted pure mixture, should swallow quickly and avoid sucking the medicine in the mouth. If necessary, you can drink with a sip of water.

Dosage

Medicines for adults and children> 15 years old

1 pack each (10ml), 4 times a day.

may reduce the dose after the symptoms have improved.

Do not overdose. If the symptoms are not improved in 2 weeks of treatment, the drug must be stopped and consulted by the doctor.

Dosage for children under 15 years of age has not been established.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

rarely cause serious symptoms, which can cause nausea, vomiting, digestive irritation, diarrhea or constipation.

Handling

Intravenous calcium gluconate, water rehydration, tying cards, symptomatic treatment and support. In case of renal failure, hemolysis and peritoneal divergence are necessary.

Oxetacaine overdose

Causes drowsiness, dizziness, dizziness.

Handling

Symptomatic treatment and supportive treatment.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

Common side effects

Headache, digestive disorders, nausea, anorexia, skin rash.

Side effects are rarely encountered

Dizziness, insomnia. Diarrhea or constipation, tongue inflammation, dermatitis, weakness.

Unknown frequency side effects

Hypersensitivity reactions such as itching, urticaria, angioedema, anaphylactic reaction. Increasing blood magnesia, increasing aluminum in the blood, reducing blood phosphate when used for high doses in patients with low diets, phosphorus can lead to bone pepper, increase calcium urine and bone puree.

Instructions for handling ADR

Notify the doctor or pharmacist when encountering the side effects of the drug for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Hypersensitivity to any ingredients of the drug.

Precautions when using

Using large doses of this product can cause or worsen intestinal obstruction in high -risk patients like people with kidney or elderly.

aluminum hydroxid does not absorb much through the gastrointestinal tract, so the systemic effect is very rare in patients with normal kidney function. However, taking too long doses for a long time, or even normal doses patients with a low diet with phosphorus, which can lead to decline in phosphate (due to phosphate aluminum cohesion), accompanied by increased bone resorption and increased calcium urine is at risk of bone puree. It is necessary to advise a doctor in the case of long -term use or in patients at risk of phosphate decline.

In patients with renal impairment, plasma concentrations of both aluminum and magnesi are increasing. Long -term use of high doses of aluminum salt and magnesi salt in these patients. Can lead to dementia, small red blood cells.

Hydroxid aluminum may not be safe for patients with Porphyria.

When taking the medicine, swallow quickly and avoid sucking the medicine in the mouth to avoid numbness in the oral cavity (due to the oxetacaine).

Because the product contains Oxetacaine should not use the drug continuously without a doctor's opinion.

Because this product contains sorbitol and sucrose excipients, it is not advisable to use drugs for patients with genetic disorders in fructose tolerance, glucose-galactose absorption disorders or enzyme deficiency.

The ability to drive and operate machinery

Do not use drugs for drivers or machinery and drugs that can cause headaches, dizziness, drowsiness.

Pregnancy

only use drugs for pregnant women after considering the benefits to the mother and the risk of harmful to the fetus.

Breastfeeding period

Do not take medicine for women during breastfeeding.

Medicinal interaction

antacids containing aluminum and Magnesi hydroxyd should be used from 1-2 hours away from other drugs because the drug can increase or decrease the absorption of some other drugs when used at the same time such as Tetracyclin, iron salts, chlorpromazine, levodopa, isoniazid, digoxin, ether resistant, a number of drugs Muscarinic, benzodiazepin, phenothiazin, ranitidine, indomethacin, phenytoin, nitrofurantoin, vitamin A, fluorid and phosphate.

When using antacids can cause urine alkalinization to increase the concentration of quinidine in plasma and can lead to poisoning.

Use antacids at the same time with polystyrene sulphonate, which is likely to reduce the effectiveness of plastic in connecting with potassium, causing metabolic alkaline infections in patients with renal impairment and causing reporting of reporting with aluminum hydroxid.

aluminum hydroxid and citrate salts can increase aluminum concentration, especially in patients with renal failure.

There is no report on drug interaction with Oxetacaine.

Storage

Store in a dry place, avoid light, temperatures below 30 ° C.

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