Gefbin Medisun treats allergic rhinitis, chronic indefinite urticaria (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Ebastine

Ingredient

Composition information	Content
Ebastine	10mg

Uses

Indications

Gefbin 10 mg is indicated in the following cases:

Allergic rhinitis (seasonal or year -round), with or without allergic conjunctivitis.

Chronic immortal urticaria.

Pharmacy

Ebastin has a prolonged and selective antagonistic effect on the H1 H1 receptor. After repeated use, peripheral receptor inhibitors remain constant.

pharmacokinetic

Ebastin metabolized and absorbed quickly after drinking.

Ebastin is converted almost completely into acid, metabolites with activity as CAREBASTIN, Carebastin's peak in plasma concentrations reach the concentration from 80 mg/ml to 100 mg/ml after taken from 2.6 hours to 4 hours.

Carebastin's half -life is from 15 hours to 19 hours, with 66% of the drug excreted in the urine, mainly conjugated metabolites. After using 10 mg once a day, the stable state is achieved for 3 days to 5 days with the peak concentration of plasma from 130 ng/ml to 160 ng/ml.

Before taking Gefbin Medisun treats allergic rhinitis, chronic indefinite urticaria (3 blisters x 10 tablets)

How to use

gefbin oral, can drink Ebastin during or outside meals.

Dosage

Gefbin dose for allergic rhinitis: 10 mg/day to 20 mg/day.

Gefbin dose of treatment urticaria : 10 mg/day.

Gefbin dose in patients with mild to moderate liver failure: no more than 10 mg/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? Using more drugs will not improve your symptoms, instead they can cause poisoning or serious side effects. If you suspect that you or anyone else may have overdosed Ebastin, please go to the emergency room at the closest hospital or hospital. Bring a box, shell, or pharmacy with you to help doctors have the necessary information.

Do not give your medicine to others even though you know they have the same disease or look like they may have the same disease. This can lead to overdose.

Please consult your doctor or pharmacist or product package for more information.

What to do when you forget the dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Gefbin, you may experience unwanted effects (ADR).

Some side effects recorded in research on users of this drug are:

headache, dry mouth and drowsiness.

Instructions on how to handle ADR

If you encounter any unwanted effect, stop taking the medication and immediately notify your doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Gefbin drug contraindicated in the following cases:

Patients with a history of hypersensitivity to Ebastin or any ingredients of the drug.

Patients with severe liver failure.

Precautions when taking drugs

Prolonged QT syndrome, hypokalemia, is being treated with drugs that increase QT or CYP3A4 inhibitors such as Azol antifungal group, macrolid antibiotic.

Caution used for patients with renal failure, mild to medium liver failure.

Caution used for pregnant women and nursing women.

Caution used for children under 12 years old.

Before using Ebastin, you should note the following:

Notify the doctor and pharmacist if you are allergic to Ebastin, any other drug or any ingredients in the drug. You can also ask the pharmacist for a list of ingredients.

The ability to drive and operate machinery

The drug can cause drowsiness during treatment. So do not drive and operate machinery if affected.

Pregnancy

Because there are no adequate and controlled studies, do not use this drug for pregnant women. If necessary, you should consult your doctor to consider the risk benefits.

Breastfeeding period

There is no study of Ebastin elimination by breast milk, so it is not used for breastfeeding people. If necessary to use, you should consult your doctor to consider benefits and risks.

Medicinal interaction

Medicinal interaction can change the ability of the drug or increase the effects of side effects. It is best to write a list of drugs you are taking (including prescription, non -prescription and functional foods) and for doctors or pharmacists. Do not arbitrarily take the drug, stop or change the dosage of the drug without the permission of the doctor, especially:

Simultaneous use of Ebastin with Azol antifungal drugs or macrolid antibiotics increases Ebastin's concentration in plasma and extends the QT segment.

The sedative effect of alcohol and Diazepam medicine increased when used simultaneously with Ebastin.

Series in plasma and area under the AUC curve of Ebastin's main active acid metabolites increase to 1.5 times to 20 times when taking Ebastin at meals. This increase does not change the time for the drug to reach the maximum concentration in the blood. Taking Ebastin in the meal does not change the clinical effect of Ebastin.

Ebastin has no sedative effect. However, warnings should be warned that the sedative effect on the few patients. Therefore, it is advisable to consider each individual patient before deciding to let them drive or operate machinery. This effect may be worse when patients drink alcohol or use other sedatives.

Please consult your doctor about taking medicine with food, alcohol and tobacco.

Your health status may affect the use of this drug. Tell your doctor if you have any health problems.

Storage

You should store at room temperature, avoid moisture and avoid light. No storage in the bathroom or in the freezer. You should remember that each drug may have different storage methods. Therefore, you should read carefully storage instructions on the packaging or ask the pharmacist. Keep pills out of reach of children and pets.

Expiry date: 36 months from the date of manufacture.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.