Gel Azaduo Medisun treats mild to medium acne (30g)

Dosage form Tube x 30g
Specifications Medisun
Ingredient Vietnam

Uses

Indications

Azaduo Gel 30g indicated on spot treatment mild acne to fit many acne with nucleus, lumpy acne and pus acne for adults and teenagers aged 9 and older.

Pharmacokology

adapalen:

Adapalen is a retinoid compound that has been shown to have anti -inflammatory activity in vivo and in vitro, adapalen stable with oxygen and light and no chemical reactions.

Adapalen's mechanism of action, like tretinoin, is a bound to the specific retinoic acid receptor of the nucleus, but different tretinoin is not attached to the protein of the receptor in the cytoplasm.

Adapalen when used on the skin has the effect of decomposing acne and also works on the abnormalities of the process of horny and differentiation of the epidermis, both of these cases are acne factors. The mechanism of action of Adapalen is to normalize the differentiation of epithy cyst cells and thus reduces the formation of acne.

benzoyl peroxid:

Benzoyl Peroxid works to peel off the skin, peeling the horn and antibacterial.

The antibacterial effect of benzoyl peroxid may be due to oxidation activity, which is effective on staphylococcus epidermis and propionibacterium acnes.

This effect is very useful on acne, topical form on the Benzoyl Peroxid 10% is the most widely used and is the first medicine to treat acne.

Benzoyl Peroxid also works to inhibit the bacterial system on the skin along with reducing the surface of small follicles for about 48 hours from applying the drug but a few days later to be clinically shown.

In case of severe acne, it is necessary to use more in the spot Clindamycin or Clarithromycin to inhibit the Benzoyl Peroxid -resistant bacteria that are also used to treat melasma on the skin like Tinea Pedis.

pharmacokinetics

adapalen:

In humans, Adapalen is absorbed through poor skin; In clinical trials, the adapalen concentration in plasma is not found at a measured level when used long -term on a wide skin area with acne with analytical sensitivity level of 0.15 ng/mL. Therefore, it is not possible to identify the pharmacokinetic parameters about the bioavailability of adapalen when applying on the skin.

benzoyl peroxid:

The drug absorbed through the skin is about 1.8 mcg/cm or 45% of the dose for about 24 hours.

The amount of benzoyl peroxid is absorbed will be completely converted into a benzoic acid in the skin and is quickly excreted into the urine benzoyl peroxid applied at the selected diffusion to the epidermis, then slowly to the packaging.

Before taking Gel Azaduo Medisun treats mild to medium acne (30g)

How to use

Apply a thin layer of azaduo gel 30g to the disease area after washing and dry, 1 time/day in the evening after bathing.

Avoid gel wire, lips, mucosa.

Dosage

The treatment time is determined by your doctor on the basis of your clinical state.

Clinically improved improvement appears after 1-4 weeks of treatment.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Symptoms:

may occur too fast, erythema or edema.

Management:

If the skin scales occur too quickly, the erythema or edema occurs, it is necessary to stop the drug. To quickly overcome the harmful effects, can apply cold gauze.

After the symptoms and the above manifestations have decreased, the test can be carefully used with a lower dosage if it is thought that the reaction has occurred due to overdose, not allergies.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

Unwanted effects when using Azaduo Gel 30g that you can meet.

Azaduo Gel 30g is used overly, so the unwanted effects have been recorded on the skin.

Unwanted effects can be encountered when using products containing Adapalez and Benzoyl Peroxid ingredients:

Common, 1/100

  • Dry skin, red skin in the medication area, burning sensation, skin irritation, red rash, peeling skin.
  • intense itching, redness, burning, swelling.
  • Dermatitis.
  • The pain of burning on the skin, allergic eyelids.

    On the skin and disorders in subcutaneous tissues:

    Very common, 1/100 ≤ ADR

  • Dry skin, red rash, peeling skin, red irritation skin.
  • Skin itching, tingling skin sensation, irritation of symptoms related to dermatitis).
  • skin allergies.
  • Facial swelling.

    On the skin and disorders in subcutaneous tissues:

    Common, 1/100

  • Dry skin, erythema, peeling skin, red irritation skin.
  • Itchy skin, feeling of skin pain, irritation (symptoms related to dermatitis).
  • skin allergies.

    • on the eyes:

    Some unwanted effects are unknown frequency:

  • irritates eyelids, itchy eyelids, erythema in the eyelids. eyelid swelling.

    • Azaduo Gel 30g is only used outside. Avoid contacting the drug with the eyes, mucosa, lips and mouth. If unfortunately exposed, must be washed with water.

    It is necessary to determine whether the patient is sensitive to Benzoyl Peroxid, by first trying on a small area. If irritated or dry, the number of times should be reduced.

    If itchy, red, hot, swollen or irritated, stop the drug and consult a physician or go to the nearest medical facility for the best treatment.

    If the drug does not work within 4 weeks, it is advisable to stop the drug and consult a physician.

    A round of treatment must not last more than 3 months.

    Warnings

    Before using Azaduo Gel 30g, you need to read the instructions carefully and refer to the information below.

    Contraindicated

    Azaduo gel gel 30g is contraindicated in the following cases:

  • Hypersensitivity to the ingredients of the drug.

    Be cautious when using

    adapalen and benzoyl peroxid

    Avoid contact eyes, lips, nose angle, mucosa.

    Do not apply the drug on the cut, scratched, the skin of eczema, severe burns. Avoid sunlight and electric light.

    Should guide patients with clear information to avoid early stopping the drug while still having to continue: At first there may be a slightly irritated feeling, this is not due to intolerance or allergies.

    However, the skin sensitivity should still be tested before taking the drug (applying many times on a small skin surface, for several consecutive days).

    To reduce the minimum of irritation, patients need to follow the following principles:

  • Do not apply the drug if the previous use has been irritated. Then if there is sun exposure, it is necessary to apply sunscreen.
  • Do not use ultraviolet light mat. If the irritation seems heavy or intolerant, it should be applied. If the itch is still prolonged, it should stop applying the drug. If accidentally applying the medication on the mucosa (eyes, mouth, nostrils) or eyelids, need to be washed with plenty of water. Do not apply medicine to bleeding or damaged skin.

    • adapalen

    If there is a reaction due to sensitive skin or serious irritation, it is necessary to stop using the drug.

    If irritation only occurs on the spot, patients only need to reduce the frequency of drug use to reduce symptoms until completely lost.

    Do not put the product on the eyes, mouth, nose corner, nasal mucosa. In case of occurring, it is necessary to rinse with clean water. Do not use drugs on open wounds, sunburned skin or exfoliating lips.

    also do not use the drug if the patient has severe acne or the location of acne affects many other areas of the body.

    Should reduce contact with sunlight and artificial UV radiation, including exposure lights, while using Adapelen. Patients often have to expose the sun for a long time and those who are sensitive to the sun, should be warned to be cautious. Should use sunscreen products and protective clothing when it is impossible to avoid exposure.

    benzoyl peroxid

    Mild, red, and skin -burning reactions can occur for the first time using this active ingredient. These symptoms are harmless, and usually disappear about 1 day.

    In case the allergic reactions become worse, the frequency of drug use should be reduced.

    The recommended overdose use does not increase the treatment effect of the drug, but increases the risk of unwanted effects.

    Be careful with the same cases of simultaneous use of different acne treatments, because the risk of resonance with side effects and symptoms in the patient becomes worse.

    Do not put the benzoyl peroxid cord into the eyes, nasal mucosa, mouth. In the case of preparations sticking to the eyes, it is necessary to rinse with water. Also be careful when using preparations for sensitive skin areas.

    The drug also increases the sensitivity to sunlight, so it does not expose to the light with strong light intensity and avoid sunlight.

    In case of mandatory, use sunscreen products and sunscreen tools such as masks, sunscreen ...

    If the product is wired into dyed materials (such as hair, fabric ...) can be faded or discolored.

    Not used on open wounds.

    methyl parahydroxybenzoate (E218) and propyl parahydroxybenzoate (E216) can cause allergic reactions that may be delayed.

    Propylene glycol can cause skin irritation.

    Women during pregnancy and lactation

    Pregnancy: Contraindications for pregnant women.

    Breastfeeding period: Contraindicated for breastfeeding women.

    The effect of the drug on driving and operating machinery

    Azaduo Gel 30G drug does not affect the ability to drive and operate machinery.

    Drug interaction

    drug interactions may affect the activity of the drug or cause side effects. Should notify the doctor or pharmacist a list of drugs and functional foods you are using. Do not use or increase or decrease the dose of the drug without the guidance of a doctor.

    Adapalen and Benzoyl Peroxid

    Be cautious when used with products that can cause other irritation, sulfur, resorcinol or salicylic acid.

    Products containing benzoyl peroxid can fade hair and discoloration of the fabric, so it is limited to contact with colored products.

    Do not use benzoyl peroxid when exposed to sunlight or ultraviolet rays.

    Simultaneous use with sunscreen containing paraaminobenzoic acid will change skin color for a while.

    adapalen

    No reports on interactions may occur when using Adapalen and other drugs. However, with retinoid drugs or drugs with the same mechanism of action, it should not be used simultaneously with Adapalen.

    Adapalen is stable with oxygen, light and chemical reactions. Although there is no reporting data on increased sensitivity to the safety light of adapalen on humans and animals, it is still advisable to avoid exposure to strong intensity or UV rays.

    benzoyl peroxid

    There is no report on drug interaction, but drugs have irritating, irritant and dry -drying effects not used simultaneously with Benzoyl Peroxid.

    Storage

    Leave a cool place, avoid light, temperature below 30⁰C.

    Other drugs

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

    count views

    Popular Keywords