Gel Progestogel 1% Kolmar treat benign breast diseases (80g)

Dosage form Tube x 80g
Specifications Progesterone

Ingredient

Composition information	Content
Progesterone	1%

Uses

indications

Progestogel 80 g drug is indicated in the case of:

Treatment of benign breast diseases: Simple breast pain or in combination with benign breast disease. Contribute to the growth and differentiation of milk pipes and cysts; Preventing the rapid splitting of epithelial cells caused by estrogen. Therefore, progestogel can treat benign breast disease due to absolute or relative local progesterone deficiency.

Dynamic pharmacokinetics

About 10% of topicals are absorbed through the skin, significantly increasing progesterone levels in the breast tissue without enough blood to cause systemic effects, especially in the uterus. Moreover, local progesterone significantly increases the effects of 17-Beta-hydroxysteroid dehydrogenase in the breast. In fact, this enzyme degrees oestradiol and oestron in this region and thus contributes to reducing the effects of estrogen in target tissues.

Heating effects are hardly existed due to different metabolic lines of progesterone. By crossing the skin, progesterone is transformed into reducing derivatives in the alpha position. In contrast by ordinary lines, progesterone will be transformed into heat derivatives removed in the beta position.

Before taking Gel Progestogel 1% Kolmar treat benign breast diseases (80g)

How to use

topical skin.

Dosage

Apply 1-2 measurements, each containing about 2.5 g of gel, on each breast that has been washed earlier. Gently massage until the drug is absorbed through the skin.

Squeeze the pipe in the groove on the measure of the dose to create a unit of dose.

Treatment needs to be continuous every day in the month, including menstrual period.

The average treatment time is 3-6 months. The maximum daily dose is 5 g.

Do not use this drug to treat children.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose? Progesterone overdose is very unlikely with this line.

It has noted that menstrual cycle may appear 1 to 2 days early. In this case, it is possible to treat from the 10th to the 25th day of the cycle.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using progestogel 80 g , you may experience unwanted effects (ADR).

recorded a few cases of hypersensitivity or non -specific skin irritation.

In some cases, the menstrual cycle may be 1-2 days earlier but does not affect the amount of menstruation. The light -like secretion has been recorded, but this effect is not the same as when using a equivalent dose in the usual way. Notify the doctor the unwanted effects when using the drug.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Progestogel 80 g drug contraindicated in the following cases:

Hypersensitivity to progesterone or any ingredients of the drug.

Be cautious when using

so clean the chest and hands when applying the drug.

If the menstrual cycle is irregular, this drug can be combined with progesterone or progestatif oral.

Only apply on the skin, not to drink.

This treatment is not a birth control pills.

Do not rule out the risk of unwanted side effects when applied on the skin even though there is no research or observation clearly.

The ability to drive and operate machinery

No report.

Pregnancy

should not use this medication for pregnant women. However, clinically, there is no description of the toxicity of progesterone for the fetus.

The period of breastfeeding

should not use this medication for breastfeeding women. Progesterone can excrete partially through breast milk.

Interactive drug

There is no drug interaction so far.

Storage

Store at temperatures below 25 ° C.

Other drugs

Disclaimer

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