Gellux 1g Davipharm oral discharge for short -term duodenal ulcer, benign stomach (20 packs x 15g)

Dosage form Drink
Specifications Box of 20 packs
Ingredient Sucralfat
Indication Peptic ulcer, stomach reflux, heartburn

Ingredient

Thành phần cho 15g

Composition informationContent
Sucralfat1g

Uses

indications

Gellux 1g drug is indicated in the following cases:

  • Short -term treatment (up to 8 weeks) duodenal ulcer, benign stomach ulcers, chronic gastritis. Learning

    Sucralfat is an aluminum salt of sulfate disaccarid, used for short -term treatment of duodenal and stomach ulcers. The drug has a more local effect (ulcer) than the whole body effect. When there is gastric acid, the drug forms a complex like a lake powder sticking to the damaged mucosa. The drug has a strong affinity (6-7 times higher than the normal stomach lining) for ulcerative area and affinity with duodenal ulcers larger than stomach ulcers. Therefore sucralfat creates a protective barrier in the ulcer, that protective barrier works:

  • inhibit the protein elimination effect of pepsin by preventing pepsin attaching to albumin, fibrinogen ... available on the surface of the ulcer.
  • Prevent the diffusion of H+ ions by interacting directly with acid on the surface of the ulcer.
  • sucralfate also absorbs bile acids, inhibits diffusion back to glycocholic acid and protects the gastric mucosa from being damaged by tauricholic acid. However, the effect of sucralfate on bile acid in the treatment of peptic ulcer is unclear.
  • The ability to neutralize the stomach acid of sucralfate is not large. Sucralfate's treatment dose does not have an acid -resistant effect, but when adhering to the gastric - duodenal mucosa, the acid neutralization effect is in place of sucralfate, which may be important in protecting the ulcerative area.
  • The drug appears after 1-2 hours and the time is up to 6 hours.

    Dynamic pharmacokinetics

    Absorption: Very little absorption (

    Distribution: unknown.

    Metabolism: The drug is not metabolized.

    Elimination: 90% excreted in feces, a very small amount is absorbed and eliminated through urine in the form of constant compounds.

    Before taking Gellux 1g Davipharm oral discharge for short -term duodenal ulcer, benign stomach (20 packs x 15g)

    How to use

    Take oral use, should be taken at hunger, drink before meals and before going to bed.

    Dosage

    adults and children> 15 years old

    duodenal ulcer, gastritis:

    2 g x 2 times/day (in the morning and before going to bed). Or 1 g x 4 times/day (drink 1 hour before meals and before going to bed), for 4-8 weeks, if necessary, you can use up to 12 weeks. The maximum dose of 8 g/day.

    benign stomach ulcers:

    Adults: 1 g x 4 times/day. Treatment continues until the ulcer heals (tested by laparoscopy). Usually require 6 - 8 weeks of treatment. If the patient has a clear evidence of Helicobacter pylori infection, it is also necessary to be treated to eliminate H. pylori bacteria with minimum with metronidazol and amoxicillin , coordinate with sucralfate and with an anti -acid drug such as H2 histamine inhibitors or proton pump inhibitors.

    Room recurrence of duodenum ulcers:

    1 g x 2 times/day. Treatment should not last more than 6 months. Reflected stomach ulcers are caused by Helicobacter pylori bacteria. To eliminate Helicobacter pylori, it is necessary to give a new session with sucralfate in combination with antibiotics.

    Stress ulcerative room:

    1 g x 4 times/day. The maximum dose of 8 g/day.

    Prevention of stomach and intestines due to stress:

    1 g x 6 times/day. The maximum dose of 8 g/day.

    Ulcerative mouth:

    Gargle and spit or rinse mouth and swallow 1 pack of chaos, 4 times/day.

    Children

    Preventive disease -caused ulcerative disease in children is being treated for a strong treatment, treating benign ulcerative and stomach ulcers in children.

    Under 12 years: The indications are not suitable for the formation of Gellux 1g.

    From 12 - 15 years old: 1 g x 4 - 6 times/day.

    Renal failure

    Aluminum salt is absorbed very little (

    Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

    do when overdose? However, acute oral toxicity studies in animals using the dose of up to 12 g/kg of body weight do not record the dose causing death.

    What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

    Side Effects

    When using Gellux 1g, you may experience unwanted effects (ADR).

    Common, ADR> 1/100

    Digestive: constipation.

    Uncommon, 1/1000

  • Digestive: diarrhea, nausea, vomiting, bloating, indigestion, flatulence, dry mouth.
  • Skin: itching, erythema.

  • nerve: dizziness, dizziness, insomnia, drowsiness.
  • Other unwanted effects: back pain, headache.
  • Rare, ADR

    Hypersensitivity reactions: urticaria, rhymes, shortness of breath, rhinitis, larynx spasm, enlarged face.

    Instructions on how to handle ADR

    Unwanted effects of sucralfat are rare and also rarely stop the drug. Notify physicians of unwanted effects when using the drug.

    Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    Contraindicated

    Gellux 1g drug is contraindicated in cases of sensitivity to any component of the preparation.

    Be cautious when used

    Use carefully in people with kidney failure due to the risk of increased aluminum accumulation in serum, especially when used for a long time. In case of severe renal failure, avoid use. To be out of reach of children.

    The ability to drive and operate machinery

    The drug can cause dizziness, dizziness, insomnia, drowsiness. Be cautious when driving and operating machinery.

    Pregnancy

    has not determined the harmful effects on the fetus. The drug absorbs very little through the gastrointestinal tract. However, when pregnant should only take the drug in case of essential.

    Breastfeeding period

    It is unknown whether sucralfat is distributed into milk or not. If there is a distribution into breast milk, the amount of sucralfate will also be very small, because the drug is absorbed into the body very little.

    Drug interaction

    can use antacids along with sucralfate in the treatment of duodenal ulcer to reduce pain. But do not drink at the same time as antacids can affect the attachment of sucralfate on the mucosa. Antacid should be told to drink Antacid before or after taking sucralfat 30 minutes.

    Cimetidin, ranitidin, ciprofloxacin, norfloxacin, ofloxacin, digoxin, warfarin, phenytoin, theophylin, tetracyclin when taken with sucralfate will be reduced. So take these drugs 2 hours before or after taking sucralfat.

    Storage

    In a dry place, avoid light, the temperature does not exceed 30 ° C.

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