Gemfibstad 300 Stella medicine for hyperlipidemia (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Gemfibrozil

Ingredient

Composition information	Content
Gemfibrozil	300mg

Uses

indications

Gemfibstad 300 drug is indicated as a supplementary therapy for diets and other non -drug treatments (such as exercise, weight loss) in the following cases:

Triglyceride treatment is severe or non -HDL with low HDL cholesterol. Men with HDL cholesterol hyperplasia and high risk of cardiovascular events are first in case the statin group is contraindicated or intolerant.

pharmacokinetics

No data.

Before taking Gemfibstad 300 Stella medicine for hyperlipidemia (10 blisters x 10 tablets)

How to use

Gemfibstad 300 medicine for oral.

Before starting to use Gemfibrozil, other health problems such as thyroid and diabetes must be best controlled as possible and the patient under the standard lipid reducing diet and need to continue during treatment.

Dosage

Adults: Dosage from 900 - 1200 mg/day.

The dose of 900 mg is used as a single dose of 30 minutes before dinner.

The 1200 mg dose is divided 2 times/day, 600 mg each time. The drug is taken 30 minutes before breakfast and dinner.

Elderly (over 65 years old): Dosage like adults.

Patients with mild to medium renal failure: start at a dose of 900 mg/day and evaluate kidney function before increasing the dose.

Do not use gemfibrozil for patients with severe renal impairment, liver failure.

Safety and efficiency in children have not been established.

Specific dose depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double doses to compensate for missed dose.

Side Effects

When using the drug, there are common unwanted effects (ADR) such as:

Very common

indigestion.

Common

Dizziness, headache.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Gemfibstad 300 drug is contraindicated in the following cases:

Hypersensitivity to any ingredients of the drug. History of allergic reactions or optical toxins exposed to light when taking fibrate drugs.

Be cautious when using

There has been reports on muscleitis, muscle disease and significantly increased creatinine phosphokinase (CPK) related to gemfibrozil. Tieu Co Van is rarely reported.

Avoid using in combination with HMG-CoA Reductase inhibitors.

Gemfibrozil can increase cholesterol secretion into bile, increasing the risk of gallstones. If the gallstones are suspected, need to specify the gallbladder tests. If the gallstones are detected, they need to stop treating with gemfibrozil.

Monitor serum lipid lipids: Periodically test serum lipids, and stop the drug if the effect on lipid is inadequate after 3 months of treatment.

Liver function tests should be performed periodically. If these abnormalities still exist for a long time, then stop using Gemfibrozil.

Should determine the periodic blood formula for the first 12 months when using Gemfibrozil.

The effect of the drug on driving and operating machinery

There has been no research on the effect of the drug on the ability to drive and operate machinery. A few rare cases such as dizziness, dizziness affecting the ability to drive.

Use drugs for women during pregnancy and lactation

must not use gemfibrozil during pregnancy and lactation.

Drug interaction

Gemfibozil strongly inhibits the enzymes CYP2C8, CYP2C9, CYP2C19, CYP1A2, and UDP Glucuronesltransferase (UGTA1 and UGTA3) and also inhibit polypeptide transportation of organic anion 1B1 (OATP1B1). In addition, Gemfibrozil is transformed into Gemfibrozil 1-O-β-glucuronid, which also inhibits CYP2C8 and OATP1B1.

There have been reports on hypoglycemia reaction after gemfibrozil and blood glucose (oral and insulin medications). Need to monitor blood glucose levels.

Gemfibrozil can increase the effects of vitamin K antibod anticoagulant like Warfarin, Acenocoumarol, or Phenprocoumon. The simultaneous use of Gemfibrozil with these anticoagulants requires careful monitoring of prothrombin time. Caution should be used when using antagonist anticoagulant anti -vitamin K type of Coumarin with gemfibrozil. The dosage of anticoagulants may need to be reduced to maintain prothrombin time at the desired level.

Each Gemfibstad 300 tablet contains less than 1 mmol sodium (23 mg).

Storage

Store at a temperature not exceeding 30 ° C in the original packaging, avoid moisture and avoid light.

Other drugs

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