Glomoti-M Glomed treatments for symptoms of nausea, vomiting, abdominal distention (10 blisters x 10 tablets)
Dosage form Box of 10 blisters x 10 tablets
Specifications Domperidon
Ingredient
| Composition information | Content |
| Domperidon | 10mg |
Uses
indications
Glomoti-M 10mg drug indicated in the following cases:
domperidon is dopamine resistant, similar to metoclopramid hydrochloride.
Because the drug has almost no effect on the dopamine receptors in the brain, the domperidon has no effect on mental and nerves.
Domperidon stimulates the peristalsis of the gastrointestinal tract, increases the tasting muscle tone and increases the amplitude of the pyloric muscles after meals, but does not affect the excretion of the stomach.
The drug is used to treat nausea and vomiting, both nausea and vomiting due to the use of levodopa or bromocriptin in Parkinson's patient.
Dynamic pharmacokinetics
There is no reported data.
Before taking Glomoti-M Glomed treatments for symptoms of nausea, vomiting, abdominal distention (10 blisters x 10 tablets)
How to use
Should take medicine 15 - 30 minutes before meals.
DosageAdults and children over 12 years: Take 1-2 tablets every 4 - 8 hours, no more than 8 tablets per day.
The maximum daily dose of domperidon is 80 mg.Should use domperidon with the lowest dose effective in adults and children. In case of necessity, Domperidon's dose can be increased to achieve the effectiveness of treatment, but the benefits of increasing the dose must be superior to possible risks.What do
do when overdose? Symptoms of overdose may include disorientation, sleeping chicken and foreign reactions.
Handling: There is no specific antidote to domperidon, but in case of overdose, may cause osmotic, gastric lavage, and symptomatic treatment.
What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.
Side Effects
Rare side effects such as milk melting, menstrual disorders, menstrual loss, big breasts in men, dry mouth, brief abdominal contractions.
Symptoms are very rare in children and not in adults.
The risk of severe ventricular arrhythmia and sudden death may be higher in patients over 60 years old or in patients with total daily doses greater than 30 mg.
Notify the doctor with unwanted effects when using the drug.
Warnings
Before using the drug you need to read the instructions carefully and refer to the information below.
contraindicated
Glomoti-M drug contraindicated in the following cases:
Simultaneous use of Domperidon with CYP3A4 inhibitors due to the ability to extend QT interval such as ketoconazol, otraconazole, fluconazol, voriconazole, erythromycin, clarithromycin, amiodaron, amprenir, Atazanavir, fosamprenir, indoavir, neLfinir, nelfin, nelfinir, neLfina Ritonavir, Saquinavir, Diltiazem, Verapamil, Telithromycin and anti-vomiting substances inhibit neurokinin-1 receptors in the brain.
Be cautious when using
Do not use more than 12 weeks for Parkinson's patient. Domperidon can cause some harmful effects on the central nervous system. Therefore, only domeridon for Parkinson's patient when other anti -vomiting measures are safer.
Must reduce 30-50% of the dose and drink several times a day in patients with kidney failure.
Be cautious when used in patients with hepatic failure.
Use carefully in high -risk patients such as:
The effect of the drug on driving and operating machinery
Glomoti - M does not affect or negligible on the ability to drive and operate the machine.
Pregnant or nursing women
used in pregnant women: There is very little data on using domperidon on pregnant women. To be safe, avoid using Glomoti - M for pregnant women.
Use on breastfeeding women: Domperidon excreted breast milk with low concentrations. It is not known whether the drug is harmful to babies. Therefore, do not breastfeed when the mother is using Glomoti - M.
Interactive drug
CYP3A4 enzyme inhibitors such as ketoconazol, erythromycin or ritonavir increases blood domeridon levels.
antacids or acid secretion inhibitors reduce the bioavailability of domperidon. Take these medications after meals, which is not simultaneously with domperidon.
domperidon can reduce the absorption of drugs simultaneously except paracetamol and digoxin.
Storage
Leave a cool place, avoid light, temperature below 30⁰C.
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