Glotadol Flu Glomed supports fever and long talk (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Paracetamol, dextromethorphan hydrobromid, phenylephrine, Guishesin

Ingredient

Composition informationContent
Paracetamol500mg
Dextromethorphan hydrobromid15mg
Phenylephrine10mg
Guiifenesin200mg

Uses

Indications

Glotadol Flu drug is indicated in the following cases:

  • Reduce symptoms in colds and flu such as fever, cough, mild pain, headache, sore throat, nasal congestion. In colds and flu.

    Paracetamol relieves pain by increasing pain threshold and cooling down through impact on the center of thermostats in the hypothalamus without causing stomach irritation. The Guaifenesin promotes the removal of the respiratory mucus due to sputum, the Guaifenesin also smooths the stimulated airways. Phenylephrin quickly reduces nasal congestion with prolonged effectiveness. Dextromethorphan is a cough reduction in the case of cough without sputum, acting on the cough center in the brain.

    pharmacokinetics

    There is no information.

    • Before taking Glotadol Flu Glomed supports fever and long talk (10 blisters x 10 tablets)

    How to use

    oral medication.

    Take the tablet with a glass of water.

    Dosage

    Adults and children over 12 years: take 1 tablet/time, every 6 hours, no more than 6 tablets/day.

    Children from 6 to 11 years old: take 1/2 tablets/time, every 6 hours, no more than 3 capsules/day.

    Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

    What to do when using overdose?

    Symptoms:

    Nausea, vomiting, abdominal pain and pale often appear in the first hour. Overdose of 10g or more (150mg/kg of weight in children) can cause liver cell damage, leading to complete and non -recovery liver necrosis; Metabolic acidosis and brain disease can lead to coma and death.

    In addition, the concentration of aminotransferase and plasma bilirubin increases, the prolmbin time is prolonged, which can appear after 12 - 48 hours.

    Management:

    Gastrointestinal or drinking carbon to eliminate the medication immediately taken. Intravenous injection or n-acetylcysteine ​​oral oral, distinctive antidote of paracetamol, most effectively is before the 10th hour after overdose.

    due to phenylephrin

    Symptoms:

    Overdose symptoms due to phenylephrin include excessive fatigue, sweating, dizziness, slow heart rate, serious hypertension and coma.

    Management:

    Firstly use supportive treatment measures. It is possible to use vasodilators as fast as glyceryl trinitrate in case of serious hypertension.

    Do Loratadin

    Symptoms:

    Sleep, fast heartbeat and headache.

    Management:

    Symptomatic treatment and supportive treatment. In the case of acute poisoning, the stomach should be empty by causing vomiting or gastric lavage.

    do dextromethorphan

    Symptoms:

    Nausea, vomiting, drowsiness, blurred vision, hallucinations, loss of air conditioning, respiratory failure, convulsions.

    Management:

    Immediately transfer the patient to the nearest hospital. Support treatment. Naloxon fast intravenous injection to detoxify dextromethorphan.

    In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

    What to do when forgetting a dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

    Side Effects

    When using Glotadol Flu, you may experience unwanted effects (ADR).

    Side effects because paracetamol is usually light and can recover after stopping the medication. Rarely rash, rash or urticaria. Adultery effects caused by phenylephrin include vision loss, digestive disorders, restlessness, anxiety, nervousness, abdominal discomfort, epigastric discomfort, tremor, shortness of breath, pale, hypertension accompanied by headaches and vomiting.

    Guaifenesin causes stomach -intestinal discomfort, nausea, vomiting, dizziness, drowsiness, headache, rash, reducing uric acid, urinary tract stones.

    dextromethorphan often causes fatigue, dizziness, tachycardia, nausea, redness. Occasionally urticaria and slight drowsiness. Central neurological inhibition and respiratory failure can occur in case of overdose.

    Stop using and consulting your doctor if there is a new sign of abnormal, swelling or rash, feeling nervous, dizziness and insomnia, symptoms that do not improve after 7 days or with fever.

    Instructions on how to handle ADR

    Notify the doctor with unwanted effects when using the drug.

    Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    Contraindicated

    Glotadol Flu drugs are contraindicated in the following cases:

  • Hypersensitivity to the ingredients of the drug. Asthma, chronic bronchitis or perforation, coughing.

    • Precautions when using

    paracetamol should be used carefully on alcoholic addicts, patients with weakened liver or kidney function. Do not drink alcohol during medication.

    Be cautious when using phenylephrin in people with cardiovascular disease, hypertension, narrow -angle glaucom, thyroid disease, diabetes, aortic aneurysm, atherosclerosis, elderly people over 60 years old.

    Do not arbitrarily use Guaifenesin for more than 7 days without consulting the doctor. Guidifenesin is considered unsafe when used for patients with porphyrin metabolic disorders due to drugs that cause porphyrin metabolic disorders in experimental animals. Avoid drinking alcohol during treatment with dextromethorphan. Abuse of dextromethorphan can occur when taking the drug in high doses and prolonged.

    Doctors need to warn patients on signs of serious skin reactions such as Steven-Jonhson syndrome (SJS), toxic skin necrosis syndrome (Ten) or Lyell syndrome, acute pustules syndrome (AGEP).

    The ability to drive and operate machinery

    dextromethorphan and GuaiFenesin can cause dizziness and sleepiness, so be careful when driving and operating machinery.

    Pregnancy

    has not determined the safety of paracetamol used during pregnancy related to unwanted effects that may be available to the fetus. Therefore, this medication should only be used for pregnant women when really necessary.

    Breastfeeding period

    There is no unwanted effect in breastfeeding when a mother uses paracetamol, and so the drug can be used during breastfeeding.

    Drug interaction

    paracetamol

    Long -term drinking with high doses of paracetamol may increase the effects of anticoagulants such as COMARIN or indandion derivatives.

    Simultaneous use of paracetamol and phenothiazine can cause serious fever.

    Out of too much and long -term alcohol can increase the risk of paracetamol toxicity in the liver.

    The risk of toxicity of paracetamol on the liver increases when using high -dose and prolonged paracetamol while taking enzyme induction drugs in the liver microsom such as isoniazid or anti -convulsions (including phenytoin, barbiturate, carbamazepine).

    The excretion of paracetamol may be affected and the plasma paracetamol levels may change when used with probenecid.

    Colestyramin reduces paracetamol absorption if used within 1 hour before or after taking paracetamol.

    phenylephrin

    Phenylephrin may increase the heart irritation and can cause arrhythmia such as vibration of ventricular vibration if used during anesthesia with respiratory anesthesia such as cyclopropan and halothan.

    Metabolic phenylephrin is affected by monoarmin oxydase inhibitors (Maois).

    Hypersensitivity reaction is reported when using oral phenylephrin for patients using Debrisoquin.

    Guaifenesin

    Do not use guidenesin combination preparations with dextromethorphan for patients who are taking monoamin oxydase inhibitors.

    Be careful when using the combined preparation of Guaifenesin and Phenylpropanolamine for patients with hypertension, heart disease, diabetes.

    dextromethorphan

    Serious and sometimes life -threatening reactions have been reported when using dextromethorphan in patients who are taking monoamin oxydase inhibitors.

    Dextromethorphan is first transformed through the liver by the cytochrom P450 2D6 enzyme system. Therefore, the ability to interact between dextromethorphan and these enzyme inhibitors such as amiodaron, fluoxetin, haloperidol, paroxetin, propafenon, quinidin, and thioridazin should also be noted.

    Concomitance Dextromethorphan with central neurological inhibitors such as alcohol, antihistamines and some mental medications can enhance the central neurological inhibitor.

    Storage

    Leave a cool place, avoid light, temperature below 30⁰C.

    To be out of reach of children.

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