Gomes drug 16mg Davipharm anti -inflammatory, treat rheumatoid arthritis, systemic lupus erythematosus (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Methylprednisolone

Ingredient

Composition informationContent
Methylprednisolone16mg

Uses

Indications

Gomes drugs are indicated in the following cases:

Methylprednisolon is indicated in nonspecific therapy that requires anti -inflammatory and immunodeficiency effects of glucocorticoid for rheumatoid arthritis, systemic erythema lupus, some inflammatory forms:

  • temporal arteritis and cylinder around the artery.
  • Sarcoid disease, bronchial asthma.

    Methylprednisolon also has indicated in the treatment of nephropathy syndrome.

    Pharmacokological

    Methylprednisolon is a glucocorticoid, 6-alpha-methyl derivative of prednisolon, has anti-inflammatory, anti-allergic and immunosuppressive effects. Due to methylation Prednisolon, corticosteroid effects have been eliminated, so there is very little risk of keeping Na+ and causing edema. The anti -inflammatory effect of methylprednisolon increases by 20% compared to the effect of Prednisolon, 4mg of methylprednisolon, which is valid as 20mg of hydrocortison.

    Dynamic pharmacy

    bioavailability is approximately 80%. Plasma concentration reaches a maximum of 1-2 hours after taking the drug. Biological effect time (inhibiting pituitary gland) is about 15 days, can be considered a short effect. Methylprednisolon is metabolized in the liver, like the metabolism of hydrocortison, the metabolites are excreted in the urine. Half life metabolism is approximately 3 hours.

    • Before taking Gomes drug 16mg Davipharm anti -inflammatory, treat rheumatoid arthritis, systemic lupus erythematosus (3 blisters x 10 tablets)

    How to use

    Take the tablet with a glass of water. Can be taken with food or not.

    Dosage

    The dose of Gomes should be adjusted according to the patient's medical condition and condition. The minimum dosage should be used to meet the desired treatment.

    Dosage to treat rheumatoid arthritis

    The patient is very serious: taking a dose of 12 - 16mg.

    Severe illness: Topes dose 8 - 12mg.

    Average: use 4 - 8mg dose.

    Children: dose 4 - 8mg.

    Dosage for asthma treatment

    Dosage 64 - 100mg.

    Dosage to treat body dermatitis, malignant rheumatoid fever

    Dosage 48mg.

    Dosage to treat eye diseases, allergies

    Dosage 12 - 40mg.

    Dosage for all -body lupus erythematosus

    Dosage 20 - 100mg.

    Dosage for treating blood diseases, leukemia, malignant lymphoma

    Dosage 16 - 100mg.

    Dosage to treat colon ulcers

    Dosage 16 - 60mg.

    Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

    What to do when overdose?

    What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

    Side Effects

    When using Gomes, you may experience unwanted effects (ADR).

    The common unwanted effects are:

  • Central nerve: Insomnia, nervousness is easily agitated.
    • digestion: Increase appetite, indigestion. Skin: Skin.
  • Endocrine and metabolism: diabetes.

    • Neurosomal and bone: joint pain.

  • Eyes: cataracts, glaucoma.
  • Respiratory: Nosebleeds.

    • Side effects:

  • Central nerve: dizziness, convulsions, mental disorders, fake tumors in the brain, headache, mood change, delirium, hallucinations, refreshment.
    • Cardiovascular: edema, hypertension. skin: acne, skin atrophy, bruising, tissue hyperpigmentation. nervous - muscle and bone: muscle weakness, osteoporosis, fracture.

    Other: Hypersensitivity reaction.

    Read the instructions carefully before use. If you need more information, please consult a physician, only use this medication as prescribed by a physician.

    When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

    Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    Contraindicated

    Gomes drugs are contraindicated in the following cases:

  • Patients who are sensitive to the ingredients of the drug, are using live vaccines.

    Precautions when using

    for patients with systemic doses with more dosage than physiological doses (about 6mg of methylprednisolon) for more than 3 weeks, it should not be stopped suddenly.

    corticosteroids can cover the symptoms of infection and weaken the body's natural immune response to infection.

    Some pathogenic bacteria such as tuberculosis, malaria can be incubated for many years. Methylprednisolon causes these infections to regenerate and cause dangerous diseases. Patients with tuberculosis need to use anti -tuberculosis drugs while using prolonged corticosteroids.

    Should be particularly cautious and monitor regularly when using body corticosteroids for patients with: osteoporosis (especially in women during menopause), high blood pressure, or a history of mental illness, diabetes, a history of tuberculosis, glaucoma, cirrhosis, cirrhosis, kidney failure, epilepsy, stomach ulcers, congenital factors:

    To be out of reach of children.

    corticosteroids can cause growth in developing children. So according to the instructions of the physician.

    The ability to drive and operate machinery

    There is no report on the ability to drive and operate machinery when using Gomes drugs.

    Pregnancy

    can be used for women during pregnancy, but must be cautious when using high and long -term doses.

    Breastfeeding period

    can be used for women during breastfeeding, but must be cautious when using high and long -term doses.

    Drug interaction

    methylprednisolon is a cytochrom P450 enzyme induction and is the substrate of the P450 3A enzyme, so this drug affects the metabolism of ciclosporin, erythromycin, phenobarbital, phenytoin, carbamonepin, ketoconon, ketoconon, ketoconon Rifampicin. Phenytoin, phenobarbital, rifampin and diuretics decreased potassium can reduce the effectiveness of methylprednisolon.

    methylprednisolon may cause hyperlemor of blood glucose, so higher insulin dose is needed.

    • Storage

    Leave a cool place, avoid light, temperature below 30⁰C.

    To be out of reach of children.

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