Grangel Shinpoong Deawoo oral fluid treatment for stomach ulcers - acute, chronic (20 packs)

Dosage form Box of 20 packs
Specifications Aluminum hydroxide, magnesium hydroxide, simethicone

Ingredient

Composition information	Content
Aluminum Hydroxide	0.03922
Magnesium hydroxide	0.06
Simethicone	0.006

Uses

indications

20 packs Grangel drugs are indicated in the following cases:

The treatment of acute, chronic gastric ulcer. Steam/anti -foaming Simethicon.

Two anti -acid components, Magnesi Hydroxid, are fast impact components and aluminum hydroxid is a slow impact component.

This combination creates rapid attack and increases the synthesis of buffer time. Hydroxid aluminum is a hunting agent and can cause constipation. This is balanced by the effectiveness of Magnesi Hydroxid as well as other magnesium salts that can cause diarrhea.

Dynamic pharmacokinetics

aluminum hydroxid slowly dissolved in the stomach and react with hydrocloride acid to form aluminum chloride and water.

About 17 - 30% of aluminum chloride forms absorbed and quickly excreted through the kidneys in patients with normal renal function.

Magnesi hydroxid quickly reacts with hydrochloric acid to form magnesi chloride and water.

About 15 - 30% of Magnesi Chloride forms absorbed and quickly excreted through the kidneys in patients with normal kidney function.

Simethicon is a physiological inert substance, it is not absorbed through the gastrointestinal tract or hindering the secretion of stomach acid or the absorption of nutrients. After oral, the drug is eliminated in the form of unchanged in the feces.

Before taking Grangel Shinpoong Deawoo oral fluid treatment for stomach ulcers - acute, chronic (20 packs)

How to use

Grangel drugs in the form of oral fluid, should shake thoroughly before use.

Take between meals or after eating 30 minutes - 2 hours, the evening before going to bed or when symptoms.

Dosage

conventional dose in the treatment of peptic ulcer, acute, chronic adults: 10 ml (1 pack) x 2-4 times/day.

The usual dose in the treatment of symptoms of gastric acid secretion (burning, heartburn ...), irritated gastric syndrome, gastroesophageal reflux - esophagus in adults: 10 ml (1 pack) x 2-4 times/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

Symptoms of overdose when used in combination with aluminum hydroxid and magnesium salt include diarrhea, abdominal pain, vomiting.

When high doses can activate or worsen intestinal obstruction and intestinal obstruction in patients at risk. Aluminum and Magnesi are eliminated by urinary tract; Acute overdose treatment includes use of intravenous calcium gluconate, water rehydration and increased test. In cases where renal function is impaired, hemolysis is needed or peritoneal.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using 20 packs Grangel, you may experience unwanted effects (ADR).

rarely, 1/1000

Gastrointestinal disorders: diarrhea or constipation.

Very rare, ADR

Disorders of metabolism and nutrition: increased blood magnesium in blood

Not determined frequency

Immune system disorders: Hypersensitivity reactions, such as itching, urticaria, angiography and anaphylactic reaction.

Disorders of metabolism and nutrition: increased aluminum in the blood. Reducing phosphorus in the blood, when used for prolonged or high doses or even the normal dosage of the product in patients with phosphorus diets can lead to calcium urinary, bone puree.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Grangel 20 packs of contraindications in the following cases:

Patients with active ingredients or any excipients, severe patients, kidney failure or ischemic.

Patients with severe renal failure.

Patients with blood phosphate.

Patients with hyperglycemia.

Young children, especially in children with tears or kidney failure.

Be cautious when using

need to be very careful when taking the drug for patients in the following cases:

Hydroxid aluminum can cause constipation and an overdose Magnesi salt that can reduce bowel motility; Large amounts can activate or worsen intestinal obstruction in high -risk patients such as people with renal failure or the elderly.

Hydroxid aluminum is not absorbed well in the digestive tract, and therefore the system effects are very rare in patients with normal kidney function.

However, over -do doses or long -term use, or even normal dosage in patients with phosphorus diets, can lead to decline in phosphate (due to aluminum - phosphate bonds) accompanied by an increase in bone reabsorption and increased calcium urine with the risk of bone puree.

In patients with renal failure, the concentration of both aluminum and magnesi increases. In these patients, long -term exposure to aluminum and Magnesi salt can lead to dementia and small red blood cell anemia.

aluminum hydroxid may not be safe in patients with porphyrin metabolism disorders.

This product contains sorbitol. Patients with rare genetic problems when intolerant to fructose should not be tolerated.

The ability to drive and operate machinery

Persons who often drive or operate machinery should use drugs?

Grangel does not affect the ability to drive and operate machinery.

Pregnancy

Women during pregnancy should take medicine?

Grangel's safety during pregnancy has not been established.

Due to the limited absorption of the mother, when used as recommended, the combination of aluminum hydroxid and Magnesi salt may be discharged through breast milk.

Simethicon is not absorbed from the digestive tract.

The period of breastfeeding

has no effect on infant/breastfed babies because of the exposure of nursing women's system with aluminum hydroxid, magnesi hydroxid and simethicon are negligible.

Drug interaction

drug interactions may affect the activity of the drug or cause side effects. Should notify the doctor or pharmacist a list of drugs and functional foods you are using. Do not use or increase or decrease the dose of the drug without the guidance of a doctor.

Do not simultaneously use Grangel with other drugs because Grangel can interfere with the absorption of other drugs if shared within 1 hour.

Aluminum -containing antacids can prevent the absorption of drugs such as tetracyclin, vitamins, ciprofloxacin, ketoconazole, hydroxychloroquin, chloroquin, chlorpromazin, rifampicin, cefdinir, cefpodoxim, levothyroxin, rosuvastatin.

levothyroxin can be attached to Simethicon slow down or reduce the absorption of levothyroxin.

Kidney while used with polystyrene sulphonate due to the risk of reducing the effectiveness of resin in associated with potassium, metabolized alkali in patients with renal impairment (report to aluminum hydroxid and magnesi hydroxid) and intestinal obstruction (report to hydroxid aluminum).

aluminum hydroxid and citrate may increase aluminum concentration, especially in patients with renal failure.

Storage

In closed packaging, in a dry place, avoiding light, temperatures below 30 ° C.

Expiry date: 36 months from the date of production.

Do not use overdue drugs indicated on the packaging.

Manufacturer: Shingpoong Daewoo Pharmaceutical Co., Ltd.

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