Grow - F Hanapharm solution to treat calcium deficiency (20 tubes x 10ml)

Dosage form 20 tube box
Specifications Calcium lactat pentahydrate

Ingredient

Composition information	Content
Calcium lactat pentahydrate	500mg

Uses

indications

Grow - F drugs indicated in the following cases:

Prevent and treat calcium deficiency in diseases: osteoporosis, tetany, bone puree.

corticosteroids. Calcium is known as an important agent in preventing osteoporosis, especially for women after menopause, calcium is the fifth most maximum element in the body.

Calcium is a valence metal 2 necessary in maintaining the nervous system, muscle - bone, cell membrane and capillary.

The role of calcium in bone structure and muscle contraction has been known, but calcium also plays an important role in blood clotting, neurotransmitter and electrocardiogram.

pharmacokinetics

absorption:

Calcium proactively absorbs in the duodenum and the first part of the jejunum, less absorption in the distance of the small intestine. The level of absorption depends on many factors, calcium is never completely absorbed in the stomach. To absorb occurs, calcium must be in the form of soluble or ionization. The ability to absorb calcium in the stomach can increase when calcium tolerance decreases, during pregnancy and breastfeeding when calcium demand is higher than normal.

Distribution:

After absorption, calcium will enter the extracellular fluid first, then quickly combine into the bone tissue. However, bone formation is not stimulated by calcium treatment. Bone contains 99% calcium in the body, 1% of the remaining amount simultaneously distributed between intracellular fluid and extracellular fluid.

The normal total calcium concentration in the blood is about 9-10.4 mg/dl (4.5 - 5.2 MEQ/L), but only the ionic calcium has a physiological effect.

Calcium concentration in cerebrospinal fluid accounts for about 50% of blood calcium concentration and tends to reflect the concentration of calcium ionic ionic ion. Calcium passes the placenta and reaches a higher concentration in the fetus in the mother's blood. Calcium distributed into breast milk.

Era:

Calcium is excreted mainly in stool, including non -absorbing calcium and secretion through bile and pancreatic fluid into the heart of the digestive tract. Most calcium is filtered through glomeruli and is reabsorbed in the branch on the Henle straps, nearby tubes and long -distance tubes. Only a small amount of cation is excreted in the urine.

Army hormones, vitamin D and thiazid diuretics reduce calcium secretion through urine, while other group diuretics, calcitonin and growth hormones increase cation excretion through the kidneys. Calcium elimination decreases when reducing blood calcium ionic in blood but increases corresponding when an increased calcium ion in plasma.

For adults with a moderate diet, calcium elimination can be about 250 - 300mg high per day. With a low calcium diet, the excretion usually does not exceed 150mg daily. Calcium elimination is reduced during pregnancy and the early stages of renal failure. Calcium is also eliminated through the sweat gland.

Before taking Grow - F Hanapharm solution to treat calcium deficiency (20 tubes x 10ml)

How to use

GROW - F drugs for oral. Remove the plastic tube and drink directly in the tube, which can be diluted with water or drink water after use. Can use Grow-F when hungry or full during or after meals.

Dosage

dose of Grow-F and the treatment time depends on the level of calcium deficiency.

Daily dose can be divided into small or disposable doses.

Adults and children over 12 years: Take 1-2 tubes/ time x 1-2 times/ day.

Pregnant women (the last 3 months of pregnancy): 2-3 tubes per day.

Children over 3 years old: Take 1/2 - 1 daily tube divided 1-2 times.

breastfeeding women: 2-3 tubes per day.

or as directed by the doctor for each specific case.

In the case of a lack of calcium deficiency, it is necessary to treat until the calcium value returns to normal, then it is necessary to continue treating for a few weeks with the specified dose for each specific case.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when using overdose?

Anorexia, fatigue, nausea, vomiting, headache, thirst, dizziness and increased urea content in the blood. Overdose, minimizing the use of calcium -containing preparations, dehydration and electrolyte imbalance should be overcome immediately. In the case of severe hypercalcemia, patients should be treated by sodium chloride intravenous infusion, using diuretics to increase calcium secretion through the urinary tract.

If the above method is not effective, it is possible to inject calcitonin or some other drugs such as biphosphonat, plicamycin or corticosteroids. No phosphate infusion is not injected because it can cause metastatic calcification. In case of danger, it is possible to eliminate a large amount of calcium by the peritoneal appraisal.

Patients with symptoms of calcium overdose should avoid direct contact with sunlight.

Be careful when treating an overdose for patients with liver and kidney failure.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Grow - F you may experience unwanted effects (ADR) including: vomiting, this belly or constipation.

Notify the doctor with unwanted effects when taking the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Grow - F drug contraindicated in the following cases:

Hypersensitivity to any ingredients of the drug. Digoxin.

Be cautious when using

Patients with diabetes or must follow the diet so note the amount of sugar in the preparation.

Hyperculia hypercalcemia: Hypercalcemia rare when using solitary calcium, but may occur when taking high doses in patients with chronic renal impairment. Because blood calcium hypercalcemia is more dangerous than lowering blood calcium, it is necessary to avoid excessive calcium supplementation for cases of calcium lowering. Blood calcium concentration should be monitored in the range of 9 - 10.4 mg/dl, and blood calcium concentration in general must not exceed 12 mg/dl.

Be careful when using calcium salts in patients with sarcoidosis, heart disease or kidney disease, and on patients who are taking the medication glycoside supporting the heart (see more drug interaction).

Kidney stones: Due to the main component of kidney stones are calcium salts, the calcium diet has long been considered a cause contributing to the risk of kidney stones and limiting the amount of calcium put in the has long been considered a reasonable measure to prevent kidney stones.

However, some recent studies have shown a difference between a calcium -rich diet and using calcium supplements: a diet rich in calcium can reduce the risk of kidney stones, whereas calcium supplements increase this risk. The reason may be related to oxalate, a diet rich in calcium can reduce the absorption of oxalate gastrointestinal tract and large amounts of calcium into the body that can reduce the oxalate output in the urine, leading to a reduction in the risk of stone formation; In addition, it may be related to a number of other factors in food derived from dairy (calcium supplements), but not in calcium supplements. Be careful when using drugs for children with hypokalemia due to high serum calcium levels that can reduce serum potassium concentration.

Do not use other calcium supplements.

Used for pregnant or lactating women

The product is indicated for pregnant and lactating women in cases where there is a risk of calcium deficiency.

The ability to drive and operate machinery

The drug does not cause drowsiness, so it can be used for drivers and operating machinery.

Drug interaction

drug interactions may affect the activity of the drug or cause side effects. Should notify the doctor or pharmacist a list of drugs and functional foods you are using. Do not use or increase or decrease the dose of the drug without the guidance of a doctor.

Hypercalcemia may occur when using calcium salts with thiazid diuretics (leading to reducing calcium excretion in urine) or vitamin D (leading to increased calcium absorption from the intestine).

corticosteroid: Reducing the absorption of calcium from the intestine.

Biphosphate: Concomitant treatment of calcium salt with biPhosphonate (such as alendronat, otidronate, bandronat, riseadonate) can lead to reduced biposphonate absorption from the digestive tract. To minimize the impact of this interaction, take at least 30 minutes of calcium after taking Alendronat or Riseadronat; At least 60 minutes after taking ibandronat, and not used within 2 hours before and after taking Etidronat.

Cardiac glycosides: Calcium with myocardial and toxic glycosides. The consequences can cause arrhythmia if used simultaneously (especially when calcium uses intravenous, oral risk).

iron preparations: Concomitance of calcium salt with oral iron products can lead to iron absorption, it is necessary to recommend patients to use these two preparations at different times.

Quinolones: Use of calcium salt simultaneously with some quinolon antibiotics (for example, ciprofloxacin) can reduce the bioavailability of quinolon, do not drink at the same time, should drink apart at least 3 hours.

Medicines reduces absorption with DOXYCYCLIN, TETRACYCLINE, Norfloxacin.

Tetracyclin: The complex of calcium with tetracyclin antibiotics that activate antibiotics, so do not drink at the same time, should drink apart at least 3 hours.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

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