Hà Nam Acetussal Acetussal O drinking solution in bronchitis, viscous mucus (20 tubes)

Dosage form Solution
Specifications 20 tube box
Ingredient N-acetylcysteine

Ingredient

Composition information	Content
N-acetylcysteine	200mg

Uses

indicated

Acetuss is used in the following cases:

is used as a mucus in mucus (mucoviscidosis) (pancreatic fibrosis), respiratory diseases with mucous mucus as in acute and chronic bronchitis, and regular cleansing in the air trachea. Mucus pills acting on the respiratory tract.

ATC code: r05cb01

Acetylcystein (N - Acetylcystein) is the N - Acetyl derivative of L - Cystein, a natural amino - acid. Acetylcysteine is used as a mucus and antidote when the paracetamol overdose. The drug reduces the mucus in pus or not by separating the disulfua bridge in mucoprotein and facilitates the expansion of the cough, the posture or the mechanical method.

Acetylcystein is used to protect the liver toxicity due to paracetamol overdose, by maintaining or restoring the liver's glutathion concentration, which is essential to cause the active active ingredient of paracetamol toxicity to the liver. In the overdose of paracetamol, a large amount of this metabolic substance is created because the main metabolic line (Glucuronid and Sulfate) becomes saturated. Acetylcystein converts into cystein stimulating glutathion synthesis and therefore, acetylcysteine can protect the liver if they start treatment within 12 hours after paracetamol overdose. Start treatment as soon as possible.

Dynamic pharmacokinetics

After taken, acetylcysteine is quickly absorbed in the digestive tract and has acetyl reducing liver into cysteine and is then metabolized. Achieving plasma peaks range from 0.5 to 1 hour after taking the dose of 200 to 600 mg.

Birth is in the range of 4-10% of the dose, possibly due to initial metabolism in the liver.

Selling time is 2 hours.

Renal clearance accounts for 30% of the body clearance

Before taking Hà Nam Acetussal Acetussal O drinking solution in bronchitis, viscous mucus (20 tubes)

How to use

Acetuss is used by oral. Break the plastic tube and drink directly in the tube.

Dosage

Muc mucus:

Adults: 10 ml x 3 times/day.

The first dose of 140 mg/kg, followed by 70 mg/kg, taken every 4 hours apart, total 17 times. N-acetylcistein is notified very effectively when used within 8 hours after paracetamol overdose. The effectiveness after that time, but recently, the treatment is up to 24 hours later.

What to do when overdose?

Treatment: Overdose treatment is mainly symptomatic treatment.

What to do when you forget 1 dose?

Side Effects

Acetylcysteine has a large safety limit. Although rarely clinically bronchospasmic spasm due to acetylcys-tein, it can still occur with all types of drugs containing acetylcysteine.

Common, ADR> 1/100:

Nausea, vomiting.

Sleep, headache, tinnitus.

Bronchospasm with an anaphylactic reaction.

Instructions to use ADR

The diluted acetylcystein solution may reduce the possibility of vomiting. Immediately treat anaphylaxis by subcutaneous injection adrenalin (0.3 - 0.5 ml of 1/1000 solution), 100%oxygen breathing, intubation if needed, intravenous infusion to increase plasma volume, inhaler Beta -adrenergic venoids if bronchospasm, intravenous injection of 500 mg hydrocortison or 125 mg Acetylcysteine hypersensitivity can be inhibited, including body rashes, itching, nausea, vomiting, dizziness, using anti -antihistamine first. There is an opinion that hypersensitivity is due to a more fake allergy mechanism on the basis of histamine release due to immunity.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Patients with a history of allergies to any ingredients of the drug.

Children Be cautious when using

Patients with bronchial asthma must be closely monitored during the treatment process, in case of bronchospasm, should immediately stop the treatment.

The use of acetylcystein may initially increase bronchial secretion, may appear more diluted sputum in the bronchi, need to suck to remove phlegm in the case of a patient to reduce cough.

This drug contains sodium, which should be considered in patients with strict diet.

Be cautious for those who are not tolerated.

The effect of the drug on driving and operating machinery

Acetylcystein does not affect the ability to drive and operate machinery.

Use drugs for women during pregnancy and lactation

Pregnant women:

Paracetamol overdose treatment with acetylcysteine in pregnant women is effective and safe, and is capable of preventing the toxicity of the liver in the fetus as well as in the mother.

Women who are breastfeeding:

Safe drug for breastfeeding.

Drug interaction

should not be used simultaneously Acetylcystein along with antidepressants and painkillers because cough reduction can lead to the accumulation of sulfur secretions.

Acetylcystein may reduce the concentration of carbarmazepine below treatment.

Storage

In a dry place, avoid light, temperatures below 30 ° C.

Other drugs

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