Hafenthyl 200 Hasan Medicine Treatment of Hyper Cholesterol (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Fenofibrate

Ingredient

Composition information	Content
Fenofibrate

Uses

Indications

Hafenthyl 200mg Hasan is indicated in the following cases:

Hypered blood cholesterol (type ILA), hypernoden endogenous blood triglyceride (type IV), hyperlipidemia (Type IIB & ILL) after applying a proper and appropriate diet without ineffective.

Increases secondary, persistent lipoprotein lipoprotein despite treating the cause (such as blood lipid disorders in diabetes). The drug inhibitors synthesize cholesterol in the liver, reduce the components that cause atherosclerosis and also reduce blood triglycerides. Fenofibrat is indicated to treat hyperplote lipoprotein LLA, IIB, III, IV and V along with a lipid restricted diet. Fenofibrat can reduce 20-25% of total cholesterol and 40-50% of blood triglycerides. Fenofibrat treatment needs to be continuous.

pharmacokinetics

fenofibrat absorbed right in the digestive tract along with food. Absorption of drugs is greatly reduced if taken after fasting overnight.

Hydrolyzed drugs into fenofibric acid are active, this substance is highly attached to plasma albumin. Peak concentration in plasma appears about 5 hours after taking the drug. In normal renal function, half a lifetime eliminates about 20 hours, but increases much in people with kidney disease. Fenofibric acid eliminated mainly in urine, mainly in the form of glucuronic complex.

Hafenthyl 200mg Hasan micro -microplate (fenofibrat micronised) is a new form of dosage (application of microchibatic technology), helping the absorption of fenofibrat increase 30% and bioavailability is equivalent to the 300mg dose. Therefore, Hafenthyl 200mg Hasan with low doses is still more effective and safer than the standard doses of 300mg.

Before taking Hafenthyl 200 Hasan Medicine Treatment of Hyper Cholesterol (3 blisters x 10 tablets)

How to use

oral drugs. Take medicine with meals.

Dosage

Fenofibrat treatment is necessarily coordinated with lipid restrictions, used by prolonged procedure and must be monitored regularly.

Dosage and duration of drug use decided by the doctor.

Normal dose: 1 capsule/day at meals.

Children> 10 years old: The maximum dose is 5mg/kg/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? If an overdose is suspected, symptomatic treatment and initial support measures are suspected. Hemorrhage does not have the effect of eliminating the body from the body.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Hafenthyl 200mg Hasan, you may experience unwanted effects (ADR).

Side effects are usually light and less common.

Common, ADR> 1/100

Digestive: digestive disorders, epigastric area, nausea, bloating, mild diarrhea.

Skin: rash, urticaria, no specific ban.

liver: increased serum transaminase. muscle: muscle pain.

Rare, 1/10000

Bile liver: bile stones.

genitals: loss of sexuality and impotence, reduced sperm. blood: leukopenia.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Hafenthyl 200mg Hasan is contraindicated in the following cases:

Hypersensitivity to fenofibrat or any ingredient of the drug.

Severe kidney failure.

Liver dysfunction or gallbladder disease.

Children under 10 years old.

Pregnant and lactating women.

There is an allergic reaction to light when treated with fibrats or with ketoprofen (nonsteroidal anti -inflammatory anti -inflammatory).

Caution when using

necessarily explore the liver and kidney function of the patient before treatment with fenofibrat.

If after 3 - 6 months of treatment, the blood lipid concentration does not decrease to consider additional treatments or other treatments.

Increasing blood transaminase is usually temporary. It is necessary to systematically check the transaminase enzymes every 3 months, in the first 12 months of treatment. Discontinue treatment if ASAT and ALAT increased over 3 times of normal limits.

If there is a combination of fenofibrat with oral anticoagulant drugs, enhance the monitoring of blood prothrombin levels and adjust the anticoagulant dose accordingly during fenofibrate treatment and 8 days after the drug stopped.

File complications occur in people with bile cirrhosis or gallstones.

Must regularly check the blood count.

The ability to drive and operate machinery

No.

Pregnancy

should not take this medication during pregnancy.

Breastfeeding period

There is no data used for nursing women.

Drug interaction

Contraindications for coordination

With Perhexilin: can cause acute hepatitis, likely death.

Precautions when coordinating

With HMG inhibitors of the Reductase (Statin group) and fibrats may significantly increase the risk of muscle damage and acute pancreatitis.

With cyclosporin increases the risk of muscle damage.

Fenofibrat increases the effects of oral anticoagulants, which increases the risk of bleeding.

Do not combine fenofibrat with liver toxic drugs such as Mao inhibitors, Perhexilin Maleat ...

Storage

in a dry place, less than 30 ° C. Avoid light.

Other drugs

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