Hagimox 250 DHG powder treated infection (24 packs)

Dosage form Box of 24 packs x 1.5g
Specifications Amoxicillin

Ingredient

Composition information	Content
Amoxicillin	250mg

Uses

indications

Hagimox drugs are indicated for infection treatment in the following cases:

Upper respiratory tract infections. Coli sensitive to amoxicillin.

Amoxicillin is aminopenicilin, durable in acidic environment, which has a wider spectrum than benzylpenicilin, especially anti -bacillant effects. Amoxicilin has bactericidal effects, due to inhibition of mucopeptide biosynthesis of bacterial cell walls.

Amoxicilin is active with the majority of gram -negative and gram -positive bacteria such as bacterial streptococcus, staphylococcus aureus not producing penicillinase, H. Influenzae, diplococcus pneumoniae, N. Gonorrheae, E. coli, and Proteus Mirabilis.

Amoxicilin is not active with penicillinase secretion bacteria, especially staphylococcus aureus, all pseudomonas strains and most of the Klebsiella and Entobacter strains.

Amoxicilin has a stronger printing effect than ampicilin for Enterococcus Faecalis and Salmonella spp., but less effective for Shigella spp .. The effect of amoxicillin can be wider when used simultaneously with sulbactam and clavulanic acid. There has been a notice of E. coli resistant to amoxicillin in combination with clavulanic acid (16.8%).

Dynamic pharmacokinetics

absorption: Amoxicillin sustainable in gastric acid environment. Absorption is not affected by food, faster and more completely through the digestive tract compared to ampicillin.

Distribution: Amoxicillin is quickly distributed into most tissues and fluids in the body, except for brain tissue and cerebrospinal fluid, but when the meninges are inflamed, amoxicillin is easily diffused.

Metabolism and elimination: Metabolic drugs in the liver and eliminate the kidneys. The sale time is 1.25 - 3 hours.

Before taking Hagimox 250 DHG powder treated infection (24 packs)

How to use

Hagimox medicine or after meals.

Dosage

Adults and children over 10 years: 500 mg (2 tablets) x 3 times/day.

Children 5 - 10 years old: dose 250 mg (1 tablet) x 3 times/day.

Higher dose, single dose or in short phases, used in some diseases:

3 g dose, repeat again after 8 hours to treat abscess around the teeth or repeat after 10 - 12 hours to treat uncomplicated urinary tract infections.

To prevent pericarditis in humans susceptible, for a single dose of 3 g, 1 hour before the procedure such as tooth extraction.

Use a 3 g of amoxicillin high doses 2 times/day for patients with severe or recurrent respiratory infections.

If needed, children 3 - 10 years old otitis media can be used 750 mg/time, 2 times daily, 2 days.

Patients with renal failure:

CL Creatinin clearance

No report.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Hagimox 250mg, you may experience unwanted effects (ADR).

Common, ADR> 1/100

BOARD (3 - 10%), usually appear slowly, after 7 days of treatment.

Nausea, vomiting, diarrhea. Red rash, lumpy and urticaria, especially Stevens - Johnson syndrome.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Hagimox 250 medicine is contraindicated in cases where patients have a history of allergies to any type of penicillin.

Caution when using

must periodically check the liver and kidney function during long -term treatment.

There may be severe hypersensitivity reactions in patients with a history of allergies to penicillin or other allergens, so it is necessary to carefully investigate the history of allergies to penicillin, cephalosporin and other allergens.

If allergic reactions occur such as erythema, edema, anaphylaxis, Stevens - Johnson syndrome, amoxicillin and emergency treatment must be stopped with Adrenalin, oxygen, corticosteroidal therapy intravenously and ventilation, including internal trachea and never being treated with penicilline or cephalosporin again.

The ability to drive and operate machinery

rarely affects the ability to drive and operate machinery.

pregnancy

Amoxicillin safety use during pregnancy has not been clearly defined, only used when necessary. However, there is no evidence of harmful effects for the fetus.

Lactation period

amoxicillin excreted into breast milk, so be cautious when taking the drug during breastfeeding.

Interactive drug

nifedipine increases amoxicillin absorption.

When using allopurinol along with amoxicillin will increase the ability of amoxicillin.

Probenecid reduces the secretion of amoxicillin in the renal tubules, which can increase the concentration of amoxicillin in the blood toxicity.

There may be antagonists between amoxicillin and bactericidal substances such as chloramphenicol, tetracyclin.

Storage

Store in a dry place, avoid moisture and light, temperature below 30 ºC.

Other drugs

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