Hagimox Capsules 500mg DHG medicine for infection treatment (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Amoxicillin

Ingredient

Composition information	Content
Amoxicillin	500mg

Uses

Indications

Hagimox Capsules 500mg DHG 10X10 is indicated in the following cases:

Infection treatment:

Upper respiratory infection.

Lower respiratory infections due to streptococcal, pneumococcal, non -secretic staphylococcus aureus and H. Influenzae.

Inhabulating urinary tract infections.

Gonorrhea.

Bile bacteria infection.

Skin infections, muscles due to streptococcus, staphylococcus aureus, E. coli sensitive to amoxicillin.

Pharmacy

Hagimox Capsules 500mg DHG 10X10 with the main active ingredient is amoxicilin, penicillin group antibiotics. Amoxicillin is aminopenicillin, durable in acidic environment, has a spectrum of wider effects than benzylpenicilin, especially anti -bacillus effect. Amoxicilin has bactericidal effects, due to inhibition of mucopeptide biosynthesis of bacterial cell walls.

Amoxicilin is active with the majority of gram -negative and gram -positive bacteria such as bacterial streptococcus, staphylococcus aureus not producing penicillinase, H. Influenzae, diplococcus pneumoniae, N. Gonorrhoeae, E. coli, and Proteus Mirabilis.

Amoxicilin is not active with penicillinase secretion bacteria, especially staphylococcus a staphylococcus, all pseudomonas strains and most of the Klebsiella and Entobacter strains.

Amoxicilin has a stronger printing effect than ampicilin for Enterococcus Faecalis and Salmonella spp., but less effective for Shigella spp .. The effect of amoxicillin can be wider when used simultaneously with sulbactam and clavulanic acid. There has been a notice of E. coli resistant to amoxicillin in combination with clavulanic acid (16.8%).

pharmacokinetics

amoxicillin sustainable in gastric acid environment. Absorption is not affected by food, faster and more completely through the digestive tract than ampicilin. Amoxicillin is quickly distributed into most tissues and fluids in the body, except for brain tissue and cerebrospinal fluid, but when the meninges are inflamed, the amoxicillin diffuses easily.

Amoxicillin's waste time is about 61.3 minutes, longer in infants, and the elderly. In people with kidney failure, the sale time of the drug is about 7-20 hours long. About 60% of the oral dosage of amoxicillin discharged in the urine within 6 - 8 hours. Probenecid extends the waste time of amoxicillin through the kidney. Amoxicillin has high concentrations in bile fluid and a part of feces.

Before taking Hagimox Capsules 500mg DHG medicine for infection treatment (10 blisters x 10 tablets)

How to use

oral drugs. Drink before or after meals.

Dosage

Adults and children over 12 years old

500mg (1 tablet) x 3 times/day.

Children 10 - 12 years old

250mg (1/2 tablets) x 3 times/day.

Children under 20 kg

Usually use a dose of 20 - 40mg/kg body weight/day.

Use a 3 g of amoxicillin high doses 2 times/day for patients with severe or recurrent respiratory infections. If needed, children 3 - 10 years old otitis media can be used by 750mg/time, 2 times a day, for 2 days.

Renal failure

Cl Creatinin

Ci Creatinin> 10 ml/minute: 500mg/12 hours.

or as directed by the physician.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Hagimox Capsules 500mg DHG 10X10, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Output: Ban.

Uncommon, 1/1000

Digestive: Nausea, vomiting, diarrhea.

Skin: Red rash, lumpy rash and urticaria, especially Stevens - Johnson syndrome.

Rare, 1/10000

Liver: slightly increase SGOT.

nerve: agitation, struggle, anxiety, insomnia, confusion, behavior change and/or dizziness.

blood: Anemia, thrombocytopenia, thrombocytopenia, leukemia like eosin, leukopenia, granulocytosis.

Instructions on how to handle ADR

Notify the doctor with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

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Patients with a history of allergies to any type of penicillin.

Precautions when using

must periodically check the liver function, be cautious during the long -term treatment.

There may be severe hypersensitivity reactions in patients with a history of allergies to penicillin or other allergens, so it is necessary to carefully investigate the history of allergies to penicillin, cephalosporin and other allergens.

If the allergy occurs such as erythema, edema, anaphylaxis, Stevens - Johnson syndrome, amoxicillin must be stopped and emergency treatment with adrenalin, oxygen breathing, corticosteroidal therapy intravenously and ventilated, including intravotics and never being treated with penicilline or cephalosporin again.

The ability to drive and operate machinery

rarely affects the ability to drive and operate machinery.

Pregnancy

Amoxicillin safely used during pregnancy has not been clearly defined, only used when necessary. However, there is no evidence of harmful effects for the fetus.

Breastfeeding period

Amoxicillin excreted into breast milk, so be careful when taking the drug during breastfeeding.

Drug interaction

nifedipine increases the absorption of amoxicillin. When using allopurinol along with amoxicillin will increase the ability of amoxicillin, probenecid to reduce the secretion of amoxicillin in the renal tubules, which can increase the concentration of amoxicillin in the blood toxicity. There may be antagonists between amoxicillin and bactericidal substances such as chloramphenicol, tetracyclin.

Storage

In a dry place, the temperature does not exceed 30 ° C, avoiding light.

Other drugs

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