Halixol 30mg Egis Pharma treatment for bronchial asthma and bronchitis (2 blisters x 10 tablets)

Dosage form Tablet
Specifications Box of 2 blisters x 10 tablets
Ingredient Ambroxol hydrochloride

Ingredient

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Composition information	Content
Ambroxol hydrochloride	30mg

Uses

indications

Halixol 30mg drug is indicated in the following cases:

Treatment of acute and chronic respiratory obstruction diseases such as bronchial asthma and bronchitis, bronchiectasis due to the production of too much mucus and talks. Benzylamine of mucus destruction compounds.

Ambroxol increases the production of lysosomes and enhances the effects of hydrolysis enzymes in mucus cells, thereby promoting bronchial secretion, cutting mucopolysaccharides. At the same time, the stimulating fluid lines make the secretion less dense. In respiratory infections, ambroxol stimulates the production of surfactants and has the effect of enhancing the cleaning of mucus.

Dynamic pharmacokinetics

Ambroxol is absorbed almost completely from the digestive tract. The drug is strongly metabolized through the initial metabolism in the liver. Absolute bioavailability of ambroxol when taken orally about 60%.

About 80% of the blood in the blood is connected to plasma proteins.

There are about 80% of the dose is excreted in the urine in the form of unproven and in the form of glucuronide of oxidant metabolites. The metabolic process undergo 2 phases and the apparent sale time of the two phase corresponding to 1.3 and 8.8 hours.

Patients with severe renal impairment: Ambroxol's waste time increases in patients with severe renal impairment, so it is necessary to reduce the dose or increase the gap between the drug use in these patients.

According to preclinical studies, Ambroxol passes the placenta and the concentration of the drug in the fetal serum 2-4 times higher than the drug concentration in the mother's body.

Ambroxol is also found in breast milk and cerebrospinal fluid.

Before taking Halixol 30mg Egis Pharma treatment for bronchial asthma and bronchitis (2 blisters x 10 tablets)

How to use

oral medication.

Should take medicine with plenty of water after eating. Drinking plenty of water during treatment will help increase the dissolving effect of ambroxol mucus.

Dosage

Adults and children over 12 years: Daily recommended dose for the first 2-3 days is 1 capsule 3 times/day, the following days use 1 tablet of 2 times/day or ½ capsule 3 times/day.

Children 5 - 12 years old: The usual dose is ½ tablet x 2-3 times/day.

In patients with severe renal impairment, need to reduce the dose or increase the distance between drug use.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose? When the drug is overdose, the first thing to do is vomit and add drinking water (milk or tea). If the drug is overdosed within 1-2 hours earlier, gastric lavage should be carried out. Activated carbon can be used and treated symptoms after detoxification. Need to continue monitoring the circulatory system.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Halixol 30mg, you may experience unwanted effects (ADR).

Rare, ADR

Neurology: headache.

Digestive: diarrhea, vomiting, digestive disorders.

Skin and subcutaneous tissue: Ban skin.

Body: Weakness.

Instructions on how to handle ADR

Notify the doctor with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Halixol 30mg contraindicated drug in the following cases:

Hypersensitivity to Ambroxol, Bromhexine or any ingredients of the drug.

Gastrointestinal ulcers.

Pregnant and lactating women.

Be cautious when using

need to take into account the possibility of a hypersensitivity reaction when using Halixol.

It is necessary to be especially cautious when using Halixol 30mg for patients with tracheological disorders or patients with too many talks.

Be careful when taking the drug for patients with lactose intolerance because each Halixol 30mg tablet contains 84 mg of lactose.

The ability to drive and operate machinery

There is no evidence that the drug affects the ability to drive and operate machinery.

Pregnancy

Preceptic data: So far has not been observed to have a teratogenic effect in preclinical studies.

On humans: Do not use Halixol 30mg for pregnant women.

breastfeeding period

Do not use Halixol 30mg for breastfeeding women.

Drug interaction

When used simultaneously with other antibiotics (for example, Amoxicillin, Cefuroxime, Erythromycin, Doxycycline), Ambroxol increases antibiotic concentration in lung parenchyma. Do not simultaneously use halixol and anti -cough drugs (eg codeine) because it can hinder the excretion of dissolved by ambroxol.

Storage

Store to avoid light, temperatures below 30 ° C.

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Disclaimer

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