Halocto Ha Nam drugs with respiratory mucus (20 tubes x 5ml)
Dosage form Oral solution
Specifications Box of 20 tubes x 5ml
Ingredient Ambroxol hydrochloride
Ingredient
Thành phần cho 5ml
| Composition information | Content |
| Ambroxol hydrochloride | 30mg |
Uses
Indications
Target respiratory mucus, used in the following cases:
Acute and chronic respiratory disease is accompanied by an abnormal hyper -secretion, especially in the acute batch of chronic bronchitis, bronchial asthma, bronchitis.
Pharmacology
Pharmacological group: cough pesticides, sputum sputum acting on the respiratory tract.
Code ATC: R05cb06
Mechanism:
Ambroxol is a metabolic of bromhexin, which has the same effect and uses like bromhexin. Some documents stated that Ambroxol has the effect of improving symptoms and reduces the number of exacerbations in severe chronic obstructive pulmonary disease.The recent research results show that ambroxol is anti -inflammatory and has the activity of antioxidants. In addition, Ambroxol also has local anesthetic effect through sodium channel blockers in the cell membrane. Ambroxol can stimulate synthesis and excretion of alveolar activity. The drug is considered an alveolar activity. However, the drug is not effective when used for mothers to prevent respiratory failure syndrome in infants, but the drug is modest when treating early for children.
Ambroxol also has the effect of excreting uric acid through urine.
Dynamic pharmacokinetics
Ambroxol are almost completely absorbed after drinking. The drug is linked to plasma protein about 90%. Ambroxol's disposal time is 7 - 12 hours.
Ambroxol passes through the amniotic fluid and the placenta, it is excreted into breast milk.
Ambroxol metabolizes through the liver. Metabolic through the liver for the first time reduces 1/3 of Ambroxol.
Ambroxol and metabolites are excreted through the kidneys about 90%.
In patients with severe liver failure, the ambroxol clearance decreased by 20 - 40%.
In patients with severe renal impairment can lead to ambroxol accumulation.
Before taking Halocto Ha Nam drugs with respiratory mucus (20 tubes x 5ml)
How to use
oral medication. Use after meals
Dosage
Adults and children over 12 years: in the first 2-3 days, 5 ml/time, 3 times a day (equivalent to 90 mg of Ambroxol). After that is 5 ml/time, 2 times a day is equal (equivalent to 60 mg of ambroxol). Can increase the effectiveness of treatment by taking 10 ml/time, 2 times a day (equivalent to 120 mg of ambroxol).
Children from 6 - 12 years old: 2.5 ml/time, 2-3 times a day, divided evenly (8 hours - 12 hours/time) (equivalent to 30 - 45 mg of ambroxol)
Children from 2 - 5 years old: 1.25 ml/time, 3 times a day (equivalent to 22.5 mg of ambroxol)
Children under 2 years of age: Do not use for children under 2 years old.
If after 5 days (children under 6 years old: after 3 days) Symptoms do not improve or become worse, please contact your doctor.
What to do when overdose?The most frequent overdose is diarrhea and stress. Excessive overdose such as nausea, vomiting, hypotension.
Therapies such as anti -vomiting, gastric lavage are not applied because it is only effective in case of extremely overdose. When there is expression of ambroxol overdose is mainly treated.
What to do when forgetting a dose?
Side Effects
The most common side effect is diarrhea.
The following terms are used to classify adverse reactions based on frequency:
Warnings
Before using the drug you need to read the instructions carefully and refer to the information below.
Contraindicated
Patients with a history of allergies to any component of the drug.
Patient with peptic ulcer
Caution when using
Caution with children under 2 years old.
Be cautious in the case of gastrointestinal ulcers and cases of coughing up blood, as ambroxol can dissolve fibrin clots and bleed again.
Only ambroxol treatment is short, does not have to be able to visit again.
Products containing caution for those who are not tolerated.
Preparations containing sodium benzoate, cautious with people sensitive to sodium benzoat.
The effect of drugs on driving and operating machinery
There is no research on the effect of the drug on the ability to drive and operate machinery in references.
Use drugs for women during pregnancy and lactation
Pregnant women
If you are pregnant or breastfeeding or suspected pregnancy or intending to get pregnant, ask your doctor or pharmacist to be privately used when taking this medication.
There is no bad side effect during pregnancy. However, the use during pregnancy is not recommended, especially in the first 3 months of pregnancy.
Women who are breastfeeding
There is no information on Ambroxol's concentration in breast milk, so be careful to use the drug while breastfeeding.
Drug interaction
The use of Ambroxol combination with anti -drugs they can lead to serious respiratory obstruction due to cough reflexes.
The use of ambroxol combined with antibiotics (amoxicillin, cefuroxime, erythromycin) leads to an increase in antibiotic concentration in mucus.
There is no report on clinical interactions related to other drugs.
Storage
Leave a cool place, avoid light, temperatures below 30⁰C.
To be out of reach of children, read the instructions carefully before use.
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