Hapenxin Kids 250 DHG treat infections (24 packs)

Dosage form Box of 24 packs x 1.4g
Specifications Cephalexin

Ingredient

Composition information	Content
Cephalexin	250mg

Uses

Indications

Hapenxin Kids 250 drugs are indicated in the following cases:

Treatment of bacterial infections caused by sensitive bacteria, does not specify the treatment of severe bacterial infections:

Respiratory infections, Ear ear, nose and throat: sinusitis, tonsillitis, otitis media, tooth infection, especially in the pharyngeal infection due to streptococci.

Skin infection, soft tissue and bone.

Urinary tract infections - genital: cystitis, gonorrhea and syphilis (when using inappropriate penicillin).

Preventive: recurrent urinary tract infections. Replace penicillin treatment for patients with heart disease must be reduced.

Pharmacokology

Hapenxin Kids 250 with the main active ingredient is Cephalexin, antibiotics of Cephalosporin group 1, have bactericidal effects by inhibiting bacterial cell synthesis. Cephalexin is sustainable with staphylococcus penicilinase, so the drug works for staphylococcus aureus strains of penicillin -resistant penicillin (or ampicilin).

cephalexin has the effect of printing in vitro on the following bacteria: Streptococcus beta blood-soluble, staphylococcus, including coagulase strains (+), coagulase (-) and penicilinase, Streptococcus Pneumoniae, some Escherichia coli, Protect Mirabilis, some Klebsella SPPSELLA SPPPALLI. Branhamella Catnrhalis, Shigella, Haemophilus Influenzae often reduces sensitivity. Cephalexin also works on the majority of ampicillin -resistant e.coli.

Most Enterococcus strains (Streptococcus Faecalis) and a few staphylococcus strains are resistant to cephalexin. Proteus indol is positive, some Enterobacter spp., Pseudomonas Aeruginosa, Bacteroides spp. When testing in vitro, Staphylococcus shows cross -resistance between cephalexin and methicilin antibiotics.

Currently, there have been many resistance strains with cephalexin, so when used, it is necessary to pay attention to local resistance.

pharmacokinetics

cephalexin is almost completely absorbed in the gastrointestinal tract and reaching the peak concentration of plasma at about 18mcg/ml after an hour with a dose of oral 500mg. Drinking cephalexin along with food can slow down the ability to absorb but the total amount of drugs absorb does not change.

15% Cephalexin dose is connected to plasma proteins. Cephalexin passes the placenta and excreted the breast milk with a low degree.

Sell waste time is 0.5 - 1.2 hours but longer in infants (5 hours) and increase when kidney function decreases. About 80% of the dosage excreted urine in the form of unchanged, so Cephalexin is also used to prevent recurrent urinary tract infections.

Before taking Hapenxin Kids 250 DHG treat infections (24 packs)

How to use

Take oral use. Mix medicine with sufficient amount of water (about 5 - 10ml of water for 1 pack), stirring before drinking. Take medicine before meals.

Dosage

Need to use the drug in accordance with the course. Treatment time should last at least 7 - 10 days.

Adults and children over 12 years old

Use 500mg (2 packs) x 4 times/day, depending on the degree of infection. The dose can be up to 1g (4 packs) x 4 times/day (dose 4g/day).

Children

Use 25 - 60mg/kg body weight/day, divided into 2 times.

specifically as follows:

Children under 2 years old: 1/2 - 1 pack of 2 times/day.

Children from 2 - 5 years old: 1 - 2 packs x 2 times/day.

Children from 6 - 12 years old: 2 - 4 packs x 2 times/day.

Adjust the dose when kidney failure

Creatinin clearance> 50ml/min, serum creatinine

Creatinin clearance 49 - 20ml/min, serum creatinine 133 - 295micromol/l, maintenance dose up to 1g, 3 times in 24 hours.

Creatinine clearance 19 - 10ml/min, serum creatinine 296 - 470micromol/I, maintenance dose up to 500mg, 3 times in 24 hours.

Creatinine clearance

or as directed by the doctor.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Nausea, vomiting, diarrhea, can cause hypersensitivity and seizures, especially in patients with renal failure.

How to handle

Protects the respiratory tract of patients, support ventilation and infusion. Give activated carbon many times instead or add to gastric lavage. Need to protect the respiratory tract of the patient while gastrointestinal or active carbon.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Hapenxin Kids 250, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Diarrhea, nausea.

Uncommon, 1/1000

Eosin leukemia. Rash, urticaria, itching. Increase liver transaminase recovery.

Rare, ADR

Headache, dizziness, anaphylactic reaction, fatigue.

Neutral leukopenia, platelet reduction.

Gastrointestinal disorders, fake colitis.

Stevens - Johnson syndrome, diverse roses, lyell syndrome, edema.

Hepatitis, jaundice.

Genital itching, vaginitis, interstitial nephritis.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Hapenxin Kids 250 is contraindicated in the following cases:

Sensitive to cephalosporin.

There is a history of anaphylaxis due to penicillin or other severe reactions through IgE.

Be cautious when using

cephalexin is usually well tolerated even in patients with penicillin allergies, but there are also very few cross -allergens.

Using long -term cephalexin can cause excessive growth of uncertainty bacteria (for example: Candida, Enterococcus, Clostridium difficile), in this case, stop the drug.

There has been a notice of fake colitis when using broad -spectrum antibiotics, paying attention to the diagnosis of this disease in patients with severe diarrhea during or after antibiotic use. Must reduce the dose when there is renal failure. Cephalexin may cause false positive when testing the urinary glucose with Benedict solution, fehling or clinitest tablets, which can be positive for Coombs and affect the quantitative creatinine with alkaline picrates.

The ability to drive and operate machinery

rarely affects the ability to drive and operate machinery.

Pregnancy

There has been no signs of toxicity for pregnancy and monitoring. However, only cephalexin should only be used for pregnant people.

Breastfeeding period

Cephalexin concentration in breast milk is very low but should still consider stopping breastfeeding during the time the mother takes medication.

Medicinal interaction

Cephalosporin treatment simultaneously and high doses of doses and aminoglycosides or with strong diuretics that can harm the kidney function. Probenecid can increase and prolong plasma concentrations and toxicity of cephalosporin.

Storage

In dry, the temperature does not exceed 300C, avoiding light.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.