HEPEVEREX 5G OPV medicine helps to enhance liver detoxification, treatment of cirrhosis (10 packs)

Dosage form 10 package box
Specifications L-Ornithine-L-ASPARTATE

Ingredient

Composition information	Content
L-Ornithine-L-ASPARTATE	3G

Uses

Indications

HEPEVEREX® is indicated in the following cases:

Simultaneous treatment of diseases or complications due to the decline in liver detoxification (e.g. cirrhosis) with symptoms of clear or potential or non -potentially hyperglycemia in the blood ammonia. liver.

L-Ornithin-L-Aspartat is a combination of two amino acids that play an important role in the metabolic cycle in the liver. The activity of L-Ornithin-L-Aspartat in the body through the amino acids L-Ornithin and L-Aspartat with two paths of ammonia detoxification: Urea and glutamine synthesis.

The synthesis of urea takes place in liver cells around the door. In these cells, Ornithin is both the active substance of two enzymes ornithin carbamoyl transferase and carbamoyl phosphate synthetase and a substrate for urea synthesis.

Glutamine synthesis is taken place in liver cells around the vein. Under special pathological conditions, aspartat and other dicarboxylate, including ornithin metabolic products, are put into cells used in the form of glutamin -linked to ammonia.

Physiological and pathological, glutamate as amino acid bonding substance with ammonia, this is not only a non -toxic form of ammonia excretion, but also activating important urea cycles (inter -cell glutamine exchange).

In physiological conditions, Ornithin and asparrtat are unlimited for urea synthesis.

Research on animals shows that the increase in glutamin synthesis is an effective mechanism of ammonia decrease.

Some clinical studies show that there is an improvement in the ratio of amino acids in the form of branches and ring forms.

pharmacokinetics

L-Ornithin-L-Aspartat is quickly absorbed and separated into L-Ornithin and L-ASPartat. The absolute oral bioavailability of L-Ornithin-L-Aspartat is about 80%. The sale time of both amino acids is short from 0.3 to 0.4 hours.

A part of L-Aspartat is also found in urine in the form of unprocessed.

Before taking HEPEVEREX 5G OPV medicine helps to enhance liver detoxification, treatment of cirrhosis (10 packs)

How to use

oral drugs. Dissolve the drug in an appropriate amount of water (a glass of pure water, tea or fruit juice), and drink after meals.

Dosage

Adults: Unless otherwise specified, the usual dose is 1 pack x 1-2 times/day.

Adolescents and children: Not enough data to use drugs for children and adolescents.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose?

Notice immediately to the doctor or the nearest hospital.

Remember to bring the remaining medication label or the remaining medication for the doctor to know the drug you used.

What to do when you forget a dose? If the time is near the next dose, skip the forgotten dose and use the next dose to the normal plan. Do not double the dose.

Side Effects

When using Hepeverex®, you may experience unwanted effects (ADR).

Uncommon, 1/1000

Digestive: Nausea, vomiting, abdominal pain, flatulence, diarrhea.

Very rare, ADR

Bone muscle and connective tissue: body aches.

Unknown:

The immune system: Hypersensitivity reaction, angioedema.

However, these manifestations are temporary and do not need to stop the drug.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

HEPEVEREX® is contraindicated in the following cases:

Hypersensitivity to any ingredient of the drug.

Severe renal failure (serum creatinine exceeds 3mg/100ml).

Caution when using

use high doses of L-Ornithin-L-ASPARTAT to monitor UREA concentration in serum and urine.

In the case of patients with severe liver failure, lower dose should be used (for example: 1/2 dose).

Take medicine with some water.

This drug contains:

Sorbitol. If you already know that you do not tolerate a few types of sugar, please notify your doctor before using this medication.

Aspartam. People with phenylceton and people must limit the amount of phenylalanin put into the body should not use this medication.

Sunset Yellow Lake, can cause allergic reactions.

The ability to drive and operate machinery

Depending on the condition, the ability to drive, operate machinery, work on high and other cases are also affected during the treatment process with L-Ornithin-Enpartat.

Pregnancy

There is no clinical data on the use of L-Ornithin-L-Aspartat during pregnancy. L-Ornithin-L-Aspartat reproductive toxicity studies are only limited to animal research tests. Therefore, avoid using drugs during pregnancy. However, if treatment with L-Ornithin-L-Aspartat is considered necessary, but the benefits and risks should be carefully assessed.

Breastfeeding period

Whether L-Ornithin-L-Aspartat does not enter breast milk or not. Using drugs during breastfeeding should be avoided. However, if treatment with L-Ornithin-L-ASPARTAT is considered necessary, the benefits and risks should be carefully assessed.

Drug interaction

There has been no report on the interaction of L-Orinithin L-ASPARTAT with other drugs.

Storage

Store at temperatures below 30 ° C, in a dry place, away from light.

Other drugs

Disclaimer

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