Hidrasec 100mg Chiesi medicine for acute diarrhea (2 blisters x 10 tablets)

Dosage form Box of 2 blisters x 10 tablets
Specifications Racecadotril

Ingredient

Composition information	Content
Racecadotril	100mg

Uses

indications

Hidrasec 100 mg drug is indicated in the following cases:

Treatment of acute diarrhea symptoms in adults. Thiorphan is an enzalphalinase inhibitor (a peptidase enzyme of the cell membrane in different tissues, especially the epithelium of the small intestine) and this enzyme contributes to the digestion of external peptides and decomposes endogenous peptides such as enkephalins.

Therefore, Racecadotril protects enkephalins from decomposition, thus prolonging their effects in enkephalinergic nerve joints in the small intestine and reducing the secretion process. Therefore RaceCadotril is an anti -intestinal activity. It reduces the secretion of water and electrolytes of the intestine caused by toxins or caused by inflammation, and does not affect the basic excretory activity. Racecadotril has an anti -diarrhea effect quickly without changing the time of transportation through the intestine.

racecadotril does not cause bloating. During clinical research, Racecadotril causes secondary constipation at the ratio equivalent to placebo. When used oral, the drug only acts on the periphery, without affecting the central nervous system.

pharmacokinetics

racecadotril is quickly absorbed after drinking. Racecadotril's bioavailability is not changed by food but the top concentration is slowed about 1 hour and 30 minutes. 90% of the active metabolites of racecadotril are thiorphan linked to plasma proteins, mainly albumin.

racecadotril is quickly hydrolyzed into thiorphan - an active metabolitus, then continues to be converted into no longer active metabolites. Racecadotril is eliminated in the form of metabolism that is active and non -activity, mainly through urine, and has much less level through the fertilizer.

Before taking Hidrasec 100mg Chiesi medicine for acute diarrhea (2 blisters x 10 tablets)

How to use

Take oral use.

Dosage

starts with 1 tablet, not to mention the time of drinking.

then take 1 capsule, 3 times/day before each main meal.

Should continue treatment until the division returns to normal.

The treatment time does not last more than 7 days. Do not treat long -term treatment with racecadotril.

Children

There is a separate form of preparation for children and children.

Elderly

No dose adjustment in the elderly.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose? In adults, single doses of over 2 g are equivalent to 20 times the treatment has been used without causing harmful effects.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Hidrasec 100 mg, you may experience unwanted effects (ADR).

Uncommon, 1/1000

Infection: tonsillitis.

Skin and subcutaneous tissue: rash, erythema.

Unknown frequency ADR

Hypersensitivity reactions: Diverse roses, tongue edema, face edema, eyelid edema, angioedema, urticaria, nodules, papules, itching.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Hidrasec 100 mg is contraindicated in the following cases:

People with allergies (sensitive) with the active ingredient or any component of the excipient.

Patients with angioed angels when using enzyme inhibitors Angiotensin (such as captopril, enalapril, lisinopril ...).

Be cautious when using

Hidrasec use does not replace the need to drink water.

The occurrence of blood or pus in the stool and fever may show an infection or another serious illness, ensuring the treatment of the cause (eg the use of antibiotics) or the additional cause. Therefore, racecadotril is not used in these cases. Racecadotril can be used simultaneously with antibiotics in case of acute diarrhea as a bacterial treatment as an additional treatment.

Do not use racecadotril in case of diarrhea related to antibiotic and chronic diarrhea due to not having enough data.

Data on patients with liver failure and renal failure are limited. Be careful when treating these patients.

Hidrasec can also reduce bioavailability in prolonged vomiting patients.

The ability to drive and operate machinery

racecadotril does not have or negatively affect the ability to drive and use machinery.

Pregnancy

There is no adequate data on the use of racecadotril in pregnant women. Animal studies do not indicate direct or indirect harm to pregnancy, fertility, embryo development, childbirth or development process after birth. However, because there is no specific clinical research, racecadotril should not be used for pregnant women.

Breastfeeding period

Due to the lack of information about the excretion of racecadotril in breast milk, this medication should not be used for breastfeeding women.

Drug interaction

Angiotensin transferring enzyme inhibitors (such as captoil, enalapril, lisinopril ...) causing angioed, this risk can increase when used with racecadotril.

Loperamid and Nifuroxazide do not change the way Racecadotril's activity in the body when these drugs are used simultaneously.

Storage

Store drugs in original packaging, below 30 ° C, avoid moisture.

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