Histalong - L 5mg Dr. Reddy Treatment of allergic rhinitis (2 blisters x 10 tablets)

Dosage form Film bag tablets
Specifications Box of 2 blisters x 10 tablets
Ingredient Levocetirizine
Indication Rhinitis, allergic rhinitis, eczema

Ingredient

Composition information	Content
Levocetirizine	5mg

Uses

indications

Histalong - L 5mg is indicated in the following case:

Treatment of allergic rhinitis symptoms (including persistent allergic rhinitis) and urticaria in adults and children aged 6 and older.

Hematopological pharmacological studies in healthy volunteers have shown that half of the levocetirizine dose is the same as the effect of cetirizine, both on the skin and nose.

In vitro studies show that levocetirizine inhibits the movement of eosinophilia through endothelial tissue causing Eotaxin in both skin and lung cells.

A study of In Vitro Pharmaceutical Research shows 3 major inhibition effects of Levocetirizine 5 mg in the first 6 hours: VCAM-1 release inhibitors, regulating blood vessels and reducing white blood cell mobilization.

pharmacokinetics

levocetirizin is absorbed quickly and completely after drinking. Levocetirizin is connected to 90%plasma proteins.

Levocetirizine distribution is limited to the distribution volume of 0.41 l/kg. The level of metabolism of levocetirizine in humans is less than 14% of the dose and therefore the difference due to genetic diversity or simultaneous use with insignificant enzyme inhibitors.

Semi -selling time in adult plasma is 7.9 ± 1.9 hours. Mid -body clearance of 0.63 ml/min/kg. Levocetirizine and metabolites are mainly excreted in the urine.

Before taking Histalong - L 5mg Dr. Reddy Treatment of allergic rhinitis (2 blisters x 10 tablets)

How to use

Histalong - L 5mg Film tablets only used for drinking, swallowing pills with water, can take medicine at meals or not.

Recommended use of drugs once a day.

Dosage

Adults and minors aged 12 years and older: recommended dose is 5 mg/day.

Children from 6 to 12 years: recommended dose is 5 mg / day.

For children from 2 to 6 years old, the dose adjustment cannot be done with film tablets. Recommendation for using levocetirizine preparations for children.

Older people: recommend adjusting the dose in the elderly with average to severe kidney failure.

Patients with renal failure: The distance between the doses must be personalized depending on the kidney function. In children with renal failure, the dose will be adjusted to each patient based on kidney clearance and body weight. There is currently no specialized data for children with kidney failure.

Patients with liver failure: No need to adjust the dose for patients only liver failure. In patients with liver failure and kidney failure, the dose adjustment recommends.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when overdose? If an overdose occurs, symptomatic treatment should be treated and used supportive measures. Consider the intestines for patients after taking the drug in a short time. Levocetirizine is not eliminated to ignore the hemolysis.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Histalong - L, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Central nerve: headache, sleep, fatigue, sleep disorders.

digestive: dry mouth, digestive disorders, vomiting, constipation.

Unknown frequency

Immune system disorders: Hypersensitivity including anaphylaxis.

Mental disorders: aggression, restlessness.

Nervous system disorders: convulsions.

eye disorders: visual disorders.

Heart disorders: suspense.

Respiratory disorders, chest and mediastinum: Difficulty breathing.

Digestive disorders: Nausea.

Hepatitis: Hepatitis.

Skin and subcutaneous tissue disorders: Neurological angels, fixed chromosomes, itching, rash, urticaria.

musculoskeletal, bone and connective tissue disorders: muscle pain.

Other: weight gain, abnormal liver function tests.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Histalong - L contraindicated in the following cases:

hypersensitivity to levocetirizine, other piperazine derivatives, or any ingredients of the drug.

Patients with severe renal failure with creatinine clearance

Caution when using

Children: It is not recommended to use film tablets for children under 6 years old because this form of preparation does not divide small doses. Recommendation to use levocetirizine for children.

Be cautious when using the drug simultaneously with alcohol.

Kidney while taking medication for patients tends to have urinary retention (such as spinal lesions, prostate hypertrophy) due to levocetirizine may increase the risk of urinary retention.

Patients with Galactose intolerance due to genetics, deficiency of lapp lactase or no absorption of glucose - galactose should not use this drug.

The ability to drive and operate machinery

Clinical studies show that levocetirizine does not impair alertness, operation or driving ability when used at the recommended dose. However, some patients may have chicken sleep, fatigue and weakness while treating levocetirizine.

Therefore patients intend to drive, participate in activities that are likely to be dangerous or operate machinery, so note this information.

Pregnancy

data on the use of levocetirizine in pregnant women is still very limited. Levocetirizine can be used during pregnancy if necessary.

Lactation period

levocetirizine can be excreted in breast milk. Harmful effects related to levocetirizine can be recorded in breastfed babies. Therefore, be careful when using levocetirizine for nursing women.

Drug interaction

Levocetirizine's studies on drug interaction has not been done (including acidic research with CYP3A4 induction substances); Studies with Cetirizine have shown that there is no harmful interactions of clinical significance (with pseudoephedrine, cimetidine, ketoconazole, erythromycin, azithromycin, glipizide and diazepam).

Mitigating Cetirizine clearance (16%) was recorded in a study using theophylline multi -dose (400 mg once a day); While theophylline distribution does not change when used simultaneously with cetirizine.

In a multi -dose ritonavir study (600 mg twice a day) and Cetirizine (10 mg / day), Cetirizine concentration increased by about 40% while ritonavir's distribution changes slightly (down 11%) when simultaneously used with Cetirizine.

Levocetirizine's absorption level does not decrease due to food, although the absorption rate decreases.

In sensitive patients, simultaneously using Cetirizine or Levocetirizine and alcohol or other Chinese nervous inhibitors may have an influence on the central nervous system.

Storage

Store less than 300C. Avoid light and moisture.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.