Hiteen skin gel Phil treat acne acne -like acne or inflammation, pus acne (10g)

Dosage form Tube
Specifications Tretinoin, erythromycin

Ingredient

Composition information	Content
Tretinoin	2.5mg
Erythromycin	400mg

Uses

indications

Hiteengel drugs are indicated in the following cases:

Micro acne treatment or inflammation, pus acne, acne acne (combined with other special treatments), acne caused by drugs such as corticosteroids, vitamin B12, vitamin D, isoniazide and drugs belonging to Barbituric, IOD, Brom.

Pharmacology

Preparation of acne treatment on the spot.

Under common conditions, acne disease is often related to many factors:

The increase in sebum secretion, the abnormalities of the keratin chemical sebum hair follicles, leading to the formation of acne and cysts.

Inflammation reaction caused by propionibacterium acnes, Staphylococcus epider-midis) and other irritants of sebum, leading to the formation of lumpy inflammation, pustules and nodules.

hiteengel has an impact on sebum secretion (tretinoin) and inflammatory reaction (erythromycin).

tretinoin stimulates cystic epithelium by increasing the proliferation of non -adhesive keratin cells. This impact easily eliminates acne and cysts has been formed. On the other hand, tretinoin promotes the process and elimination of inflammatory factors (nodules, pustules), increasing the permeability of the follicles with agents that can respond to irritants of inflammation (keratin fragments, free fatty acids ...).

erythromycin is an antibiotic of a macrolide group that is effective in acne treatment. Erythromycin has a direct impact on propionibacterium acnes, thus reducing the number of sebum follicles. Erythromycin also has anti -inflammatory effects. This effect corresponds to the decrease in the number of bacteria, the protease ratio and the ratio of free fatty acids are inflammatory causes.

Dynamic pharmacokinetics

When applied, tretinoin in Hiteengel gel is absorbed very little. Most tretinoin is lying on the multi -face, small amounts soaked into the epidermis and dermis. Tretinoin concentration in plasma is low, cannot be detected but has a very small amount of tretinoin discharged in urine within 24 hours. Tretinoin in alcohol solution and Propylene Glycol solution is absorbed through the skin more than three times than the fat tretinoin. This explains the effects of tretinoin in acne treatment.

The skin of erythromycin base is not determined. However, daily dosage with topical form is about 40 times lower than oral doses.

Before taking Hiteen skin gel Phil treat acne acne -like acne or inflammation, pus acne (10g)

How to use

topical skin.

Dosage

Usually, apply 1 time/day in the evening to the sick area after washing and drying.

Applying too much medicine can irritate that area.

Wash your hands clean after applying the drug.

Apply a amount of beans and rub well until the drug is completely absorbed into the skin.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when using overdose?

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Hiteengel, you may experience unwanted effects (ADR).

Dry skin, itching, peeling skin, red rash, red skin, edema, herpes or scales can happen differently in each person. In these cases, medication should be stopped or controlled the medication.

Increase or decrease skin pigmentation reported in some cases of continuous medication.

Contact dermatitis is reported rarely occurs.

can increase sunlight sensitivity.

Extreme weather such as wind or cold can cause irritation to patients.

The rare rash occurs, if a drug should be discontinued.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

HITEEGELEGEL CHAPTER IN THE CURRENT SCIENCE:

Hypersensitivity to this drug or antibiotics belonging to the macrolide group.

Patients with a family history of skin cancer.

Patients with eczema, fracture or skin peeling.

Patients with sunburn are recommended not to be used until the skin is completely restored.

Pregnant or suspected pregnant women and nursing women.

Patients with acute inflammation in the skin, especially around the mouth.

Caution when using

Mouse tests show that the drug may increase the condition of creating skin tumors due to the impact of light. Should avoid exposure to sunlight during the time of taking the drug. If the patient must be exposed to sunlight, avoid taking the drug on the previous day, the next day and that day.

Test drugs on a small skin before taking the drug.

To avoid bacterial resistance, attention should be paid to the sensitivity and minimum use time.

Must follow carefully because the sensitive reaction may occur. If sensitive symptoms (itching, skin redness, swelling, lumpy nodules, small herpes ...) occur, stop taking the drug.

Antibiotic resistance can occur in the case of a long -term use, stop taking the drug and use another appropriate therapy.

Should keep the pills away from the eyes, the corner of the nose, the mouth and the mucosa.

Do not allow the drug to accumulate in areas with wrinkles.

Should avoid sticking to the clothes.

The ability to drive and operate machinery

does not affect.

Pregnancy

should not be used for pregnant women or suspected pregnancy.

The period of breastfeeding

Do not take the drug in nursing women.

Medicinal interaction

should be particularly cautious when used simultaneously with sulfur, resorcinol, benzoyl peroxide, salicylic acid, clindamycin or lincomycin with hitengel because it is likely to occur drug interactions.

Patients who are taking medicine to make horns in the skin should only take Hiteengel after the horn tarpaulin has decreased effects.

Be careful when used with drugs or soap that eat skin and detergent, cosmetics with strong dry skin, highly alcoholic preparations, skin hunting, alkaline because it is likely to cause drug interactions.

Storage

Store in closed boxes, avoid light, at temperatures below 30 ° C.

Other drugs

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