Huhajo Tab 10mg JRP medicine replaces people with adrenal insufficiency (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Hydrocortisone

Ingredient

Composition information	Content
Hydrocortisone	10mg

Uses

indications

Huhajo medicine is indicated in the following cases:

Hydrocortison (or cortison) is usually corticosteroids chosen for replacement treatment for people with adrenal insufficiency (primary and secondary adrenal insufficiency, congenital adrenal hyperplasia or genital adrenal syndrome). Glucocorticoid has anti -inflammatory, anti -allergic, anti -itching and immunosuppressive effects.

pharmacokinetic

Hydrocortisone absorbs quickly from the stomach - intestine and reaches the peak concentration after an hour. Half a lifetime about 100 minutes. More than 90% of the drug is linked to plasma proteins. After absorption, hydrocortison metabolizes in the liver and in most body tissues into hydrogenation and descending as tetrahydrocortison and tetrahydrocortisol. These substances are excreted in the urine, mainly in the form of glucuronic complex and a small amount in the form of unchanged.

Before taking Huhajo Tab 10mg JRP medicine replaces people with adrenal insufficiency (10 blisters x 10 tablets)

How to use

Huhajo medicine is used oral.

Hydrocortisone and dosage lines and substances depending on the disease are being treated and responded to by the patient. After achieving the desired response, it should gradually reduce the lowest dosage to maintain satisfactory clinical response. If taking the drug for a long time, when stopping the drug, the drug must stop gradually.

Dosage

Alternative (oral)

Adrenal insecticidal, secondary adrenal insufficiency:

The usual dose: 20 mg orally early in the morning and 10 mg in the afternoon, to imitate the 24 -hour biological rhythm in the body.

congenital adrenal hyperplasia (genital adrenal syndrome):

The usual oral dose: 0.6 mg/kg/day is divided into 2 or 3 doses, along with fluorocortisone acetate 0.05 - 0.2 mg/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? In cases of overdose, no typical antagonistic drugs, only supportive treatment and symptomatic treatment.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Huhajo medicine, you may experience unwanted effects (ADR).

In long -term glucocorticoid treatment, the most common ADR is the cushing state and osteoporosis to some degree. In contrast, ADR is very rare with short -term high -dose injection therapy.

Common, ADR> 1/100

Bone muscle: osteoporosis, muscle atrophy.

Endocrine: Cushing syndrome to a certain extent, grow slowly in children; secondary response to the adrenal and pituitary shell, especially during stress, such as when injury, surgery or disease, weight gain.

Gastrointestinal disorders: peptic ulcer, bleeding sores, small intestine ulcer.

Mental disorders: excessive excitement, confusion, depression when stopping the drug.

Reaction in the skin: contact dermatitis, skin atrophy, slow healing.

Immune immune reaction, anaphylactic reaction with bronchospasm. Bacterial infections caused by chance of disease with low poison.

Instructions on how to handle ADR

Notify the doctor with unwanted effects when using the drug. If you need more information, please consult your doctor.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Huhajo medicine is contraindicated in the following cases:

Patients with infections (especially in progressive tuberculosis), viral infections (chickenpox, shingles, corneal herpes), fungal infections or parasites only use glucocorticoids after being treated with anti -infections mentioned above.

Caution when using

When using high doses, it is necessary to be very cautious in patients with osteoporosis, new intestinal connection, mental disorders, gastrointestinal ulcers, tuberculosis, hypertension due to diabetes, heart failure and in growing children.

Never use glucocorticoids in the progressive infection, unless previously used anti -bacterial drugs. On the other hand, there is still a risk of increasing infections due to immunosuppressive when using glucocorticoids.

The ability to drive and operate machinery

Precautions when used for drivers and machinery operating because the drug can cause mental disorders.

Pregnancy

Animal testing during animal pregnancy, glucocorticoids have harmful effects on pregnancy. However, these results do not correspond to humans. However, taking prolonged, high doses will cause the risk of adrenal inhibition of the fetus. Used before labor, glucocorticoids have a protective effect against respiratory failure syndrome is very dangerous for premature babies. Asthma treatment for pregnant women should combine glucocorticoids, because asthma itself is a big risk to the fetus.

Breastfeeding period

Hydrocortison excreted in milk, causing risks for children, even with normal doses.

Medicinal interaction

Simultaneous use of corticosteroids with barbiturates, carbamazepine, phenytoin, primidon, rifampicin, corticoids are increased metabolic and decreased.

When used simultaneously corticosteroids with diuretics reduce potassium, such as thiazids, furosemids, the shortage of potassium.

Simultaneous use of corticosteroids and nonsteroidal anti -inflammatory drugs will increase the rate of bleeding and peptic ulcer.

corticosteroids also change the response of patients with anticoagulants.

corticosteroid increases the need for anti -diabetes and anti -hypertension drugs.

corticosteroids can reduce serum salicylate levels and reduce the effects of anti -muscarin drugs in myasthenia gravis.

Storage

Storage in closed packaging at temperatures below 30 ° C.

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