Hyalgan injection 20mg/2ml Inj treats joint diseases due to injury and degeneration (2ml)

Dosage form Box x 2ml
Specifications Sodium hyaluronate

Ingredient

Composition information	Content
Sodium hyaluronate	20mg

Uses

indicated

Hyalgan is indicated for the following cases:

A joint disease caused by trauma and degeneration.

Support treatment in orthopedic surgery.

Pharmacology

Pharmacy - Treatment group: Drugs used to treat musculoskeletal disorders

ATC: MO9AX01.

Inject Hyalgan into joints in arthritis leads to the normalization of the viscosity and elasticity of the epidemic fluid, and activated the tissue repair process in articular cartilage.

evidence from different experimental models shows that hyaluronic acid has anti -inflammatory and analgesic activity. This feature is considered an improvement of joint function and means objective and subjective symptoms related to arthritis can be controlled.

Dynamic pharmacokinetics

External hyaluronic acid is widely present in organisms, metabolized in physiology after use on the gastrointestinal tract via conventional hexose metabolism.

Results from studies on dogs and rabbits after injection in single and repeated injections show that Hyaluronic Acid is quickly distributed into the joint tissues and lasts for a long time.

The radioactive marker can be found in the epidemic array within 2 hours after injection and lasts 7 days. The maximum concentration of the drug is marked in the epidemic fluid, then the concentration decreases in joints, ligaments and adjacent muscles.

Regarding the distribution in organs, radiation has been found in the liver, kidney, bone marrow and lymph nodes. The drug is excreted mainly through the kidneys.

A study conducted on pregnant mice showed that using intravenously showed that radiation was in the placenta and in different organs of the fetus.

Before taking Hyalgan injection 20mg/2ml Inj treats joint diseases due to injury and degeneration (2ml)

Always consult a doctor or pharmacist before deciding to take the drug.

How to use

Inject in joints.

Dosage

by the size of the joint, injected in 2 ml of Hyalgan (20 mg) or less, once a week for 3-5 weeks, depending on the severity of the disease.

Can treat simultaneously more than one joint.

Note: This dose may vary depending on the doctor's instructions. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

In case of emergency or overdose, immediately call the 115 emergency center or visit the nearest local health station.

In addition, you need to record and bring the list of drugs you have used, including prescription and non -prescription drugs.

What to do when you forget the dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Hyalgan, you may experience unwanted effects (ADR).

There have been rare cases of local injection reactions such as pain, swelling: overflow, heat, redness, itching and epidemic inflammation. In general, these reactions pass by for a few days if the joint is rested and applied ice. Only sometimes such cases can last longer and have a heavier nature.

When there are objective signs that show the manifestations of the previous chronic inflammatory process, the injection of hyaluronic acid, in some rare cases, worsen the disease.

There have been very rare cases of bacterial infections at the injection site in the joint (see "warning and caution").

There has been a very rare report on the hypersensitive reaction of the whole body (skin rash, urticaria, itching) and even more rare anaphylaxis cases, but there is no case of death results.

Instructions for handling ADR

During the use of the drug, if the body is noticeable, the reactions appear, reactions that are likely to seriously affect health, patients need to stop using the drug.

Besides, you need to quickly go to the hospital and immediately report to a specialist about the current health condition. At that time, doctors will conduct examination and propose appropriate treatment methods to avoid danger.

Warnings

Contraindicated

contraindicated drugs with cases of hypersensitivity to the active ingredient or any component of excipients; History of allergies to poultry proteins.

Caution when using

Read the instructions carefully before use. If you need more information, consult your doctor. This drug is only used by a doctor.

It is recommended not to use grade 4 ammonium salts to disinfect because the presence of hyaluronic acid will form precipitated substances.

The invasive procedure in the joints must be performed by experienced medical surgeons, techniques and in sterile conditions described for this type of injection.

Must be especially cautious in the case of a patient being infected near the injection site to avoid bacterial arthritis.

Before the injection in the joint, the patient must be carefully examined for sure any signs of acute inflammation.

If these signs, the doctor must assess whether or not to be injected or not.

If there is joint effusion, should suck the fluid before injection Hyalgan.

Do not let the joint work overload for hours after injection in the joint.

Use the right dose, do not increase or decrease the dose, as this can cause hypersensory reactions, or reduce product treatment effect.

Patients do not arbitrarily stop the product but must listen to the doctor's advice, so gradually reduce the amount of amount. The arbitrary stopping of the product can cause the body's immunity, and may increase the symptoms of some diseases.

When stopping using the product, it should be reduced slowly, not suddenly stopped. Do not put more than 2 consecutive doses.

Pregnant women

Although not seeing the effect of poisoning or teratizing from animal tests, the use of this drug in pregnant women or nursing mothers should be limited only for cases that have been evaluated by the doctor as absolute, after careful consideration of the ratio between benefits and risks.

The impact of drugs when driving and operating machinery

does not affect the ability to drive and operate machinery.

Drug interaction

Hyaluronic Acid interacts with some local anesthetic, extending anesthetic time.

To avoid drug interactions, it is best to write a list of drugs you are taking (including prescription, non -prescription, herbal and functional foods) for doctors or pharmacists.

Health condition can also affect the use of this drug. Tell your doctor if you have any health problems.

Alcohol and tobacco can interact with certain drugs. In the process of using the product, patients need to minimize foods or drinks containing alcohol or stimulants to avoid affecting the activity of the active ingredient.

Please consult your doctor about taking medicine with food, alcohol and tobacco.

Storage

Store drugs at less than 25 ° C, leave a cool dry place, avoid direct light, moisture prevention.

Do not store drugs in the bathroom, in the freezer. Each drug may have different storage methods. Please read the instructions on the packaging carefully or ask the doctor.

Do not let the product in children can be with.

Notice the appearance of the product, if the product shell shows signs of openness, the product is discolored, watery or deformed, then do not use the product. If you want to destroy, do not arbitrarily throw it into the sewer, toilet ... Instead, you should consult a doctor and pharmacist to destroy the drug safely, without causing environmental pollution.

Expiry date: 36 months from the date of manufacture.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.