Hypertel 40mg Pymepharco medicine treats high blood pressure (4 blisters x 7 tablets)

Dosage form Box of 4 blisters x 7 tablets
Specifications Telmisartan

Ingredient

Composition information	Content
Telmisartan	40mg

Uses

Indications

Hypertel 40 drugs are indicated in case of treatment of idiopathic hypertension.

Pharmacokological

Telmisartan is an Angiotensin II specific receptor antagonist (AT1 type), effective oral use. Telmisartan occupies Angiotensin II at the AT1 receptor bond position, the receptor is responsible for all the known activities of Angiotensin II. There is no Telmisartan's operating activity at the AT1 receptor. This cohesion is sustainable and prolonged.

pharmacokinetic

absorption

Telmisartan quickly absorbed. Telmisartan's absolute bioavailability is about 50%. Telmisartan's plasma plasma concentrations or food after 3 hours are similar.

When drinking with food, AUC has decreased but does not affect the effectiveness of treatment. Gender distinguishes plasma concentrations, plasma peak concentrations increased by 3 times and AUC increased by about 2 times in women compared to men, but did not affect the effectiveness of treatment.

Distribution

Telmisartan combines most with plasma proteins (> 99.5%). The average distribution volume in a stable state is 500L.

Metabolism

Telmisartan metabolizes by a reaction with glucuronid. The metabolites have no pharmacological effects. Telmisartan has a pharmaceutical properties reduced by excess 2 with the final sale time of over 20 hours.

Elimination

Telmisartan eliminates almost entirely through feces, largely in the formless form.

Before taking Hypertel 40mg Pymepharco medicine treats high blood pressure (4 blisters x 7 tablets)

How to use

take the tablet with water. Can take medicine with or not with food.

Dosage

Adults: The recommended dose is 40 mg x 1 time/day. Maximum dose can be increased by 80 mg 1 time/day to achieve target blood pressure.

Can be used in combination with Telmisartan with thiazid diuretic drugs such as hydrochlorothiazide. The coordination shows that hydrochlorothiazide has the effect of lowering communion with telmisartan.

When the dose is needed, it should be noted that the maximum lowering effect is generally achieved after 4-8 weeks of treatment.

Patients with severe hypertension: Telmisartan dose up to 160 mg used for single or combined with hydrochlorothiazide 12.5 - 25 mg/day are very good and effective tolerance.

Patients with mild and medium liver failure: Do not use more than 40 mg/day.

Patients with dialysis kidneys: The starting of the dose should be at 20 mg/day.

The elderly: No dose adjustment.

Children: The safety and effectiveness of Telmisartan has not been set up.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose? Supporting treatment should be conducted if there are symptoms of hypotension. Telmisartan is not eliminated from the body through hemolysis.

What to do when forgetting a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Hypertel 40, you may experience unwanted effects (ADR). These effects are often light and transient, rarely stop the drug.

Side effects can be encountered such as fatigue, headache, dizziness, limb edema, sweating, dry mouth, nausea, abdominal pain, renal function, hyperkalemia, cough, angioedema, visual disorders, tachycardia.

Notice an unwanted effect when using the drug.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Hypertel 40 contraindications in the following cases:

Patients who are sensitive to the ingredients of the drug.

Precautions when using

need to monitor blood potassium concentration.

Be careful when using drugs in patients with liver failure, kidney failure and kidney transplant, patients with aortic valve stenosis or mitral valve or hypertrophic heart muscle.

In patients with primary aldosterone increases will not respond to antihypertensive drugs that are impacted through inhibition of the Renin - Angiotensin system. Therefore, do not use telmisartan in these patients.

There is a risk of strong hypotension and renal failure in patients with narrowed kidney stenosis on both sides or one side when treated with Telmisartan.

Be cautious when used for patients with biliary obstruction.

The ability to drive and operate machinery

Do not use the drug when driving and operating machinery.

Pregnancy

Do not use drugs for pregnant women.

Breastfeeding period

Do not use drugs for breastfeeding women.

Drug interaction

Telmisartan may increase the effect of other antihypertensive drugs when used simultaneously. Other interactions are not significant clinical significance.

Storage

In a dry, cool place (below 30 ° C). Avoid light.

Other drugs

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