Ibuprofen 600mg Mekophar anti -inflammatory, headache, dysmenorrhea, toothache (10 blisters x 10 tablets)
Dosage form Box of 10 blisters x 10 tablets
Specifications Ibuprofen
Ingredient
| Composition information | Content |
| Ibuprofen | 600mg |
Uses
Indications
ibuprofen 600 mg is indicated for the following cases:
Pharmacokinetics
absorption
Ibuprofen pharmacokinetics are linearly connected to the dose. Get the maximum concentration in serum 90 minutes after taking the drug. Food can reduce the absorption of the drug. The sale time of the drug is 1-2 hours.
Distribution
99% ibuprofen is connected to plasma proteins. During the epidemic, ibuprofen achieved stable concentrations between the second and 8th hours after taking the drug. The maximum concentration in the epidemic accounts for about 1/3 of the maximum concentration in plasma. After taking 400 mg of ibuprofen every 6 hours in nursing women, the amount of ibuprofen found in breast milk is 1 mg/24 hours.
Metabolism
ibuprofen has no enzyme induction effect. 90% ibuprofen is metabolized in non -working form.
Elimination
Eliminate mainly through urine. Within 24 hours, 10% in the form of unchanged, 90% in non -active form, mainly in the form of an associate with glucuronic acid.
Before taking Ibuprofen 600mg Mekophar anti -inflammatory, headache, dysmenorrhea, toothache (10 blisters x 10 tablets)
How to usetake medicine right after the meal.
Dosage
Dosage for adults
Analgesic, anti -inflammatory: 1 tablet/time, 2-4 times a day. Maximum 4 tablets/day.
Antipator: ½ tablet/time, repeat this dose every 6 hours if needed. Maximum 2 capsules/day.
What dodo when overdose?
often treat symptoms and support. If you have overdose, it is necessary to apply measures to increase elimination and inactivity such as gastric wash, causing vomiting and diuretic, drinking activated carbon or salt bleach. If severe, the hemorrhage or blood transfusion.
Because the drug causes acidosis and elimination in the urine, theoretically will benefit from alkaline and diuretic infusion.
What to do when you forget the dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.
Side Effects
When taking ibuprofen 600 mg, you may experience unwanted effects (ADR).
Commonrare
Notify the doctor with unwanted effects when using the drug.
Warnings
Contraindicated
ibuprofen 600 mg is contraindicated for the following cases:
Be cautious when using
drivers and operation of machinery and elderly people.
ibuprofen can cause transaminase to increase in the blood, but this transformation is transient and recovered.
Visual disorders like blurred vision are subjective signs and are related to the harmful effects of the drug but will end when stopping ibuprofen.
ibuprofen inhibits platelet capacitors so it can cause prolonged bleeding time.
During pregnancy or lactation
Contraindications for pregnant women, especially in the last 3 months of pregnancy; breastfeeding women.
Drug interaction
ibuprofen and other nonsteroidal anti -inflammatory drugs increases the side effects of quinolon antibiotics on the central nervous system and can lead to seizures.
Magnesium hydroxide increases the initial absorption of ibuprofen, but if aluminum hydroxide is present, there is no effect.
For other nonsteroidal anti -inflammatory drugs: increased the risk of bleeding and ulcers.
methotrexate: ibuprofen increases the toxicity of methotrexate.
Furosemide: Ibuprofen can reduce the effect of sodium exit of Furosemide and diuretics.
Digoxin: Ibuprofen may increase plasma digoxin levels.
Storage
Store in dry places (moisture
Expiry date: 36 months from the date of manufacture. Do not use expired drugs.
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