Idatril 5mg Mebiphar medicine for hypertension and congestive heart failure (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Imidapril

Ingredient

Composition information	Content
Imidapril	5mg

Uses

Indications

Idatril 5 drugs are indicated in the following cases:

Hypertension. Drink 1 time. Imidaprilate inhibits the enzyme Angiotensin, resulting in reduction of angiotensin II, causing peripheral vasodilation and reducing barriers.

pharmacokinetic

absorption

Imidaprilat is an imidapril's pharmacological metabolic substance. After taking the only 10mg dose in healthy people, the imidapril concentration in plasma peaks after 2 hours, and eliminates plasma with the half -life of 2 hours. Imidaprilat reaches a peak plasma concentration after use from 6 to 8 hours about 15 ng/ml and eliminated from plasma with the half -life of 8 hours.

Distribution

Imidaprilat is widely distributed in plasma and many types of endothelial cells.

Metabolism - Elimination

Imidapril has 4 metabolites and in which Imidaprilat is active. After taking 1 single dose of 10mg Imidapril in healthy people, about 25.5% of the imidapril dose is excreted into the urine for 24 hours.

accumulation

When taken continuously for 7 days, Imidaprilate concentration in plasma is stable from day 3 to 5. There is no sign of accumulation of drugs. For people with renal function, the selling time is longer and the imidaprilate level is higher.

Before taking Idatril 5mg Mebiphar medicine for hypertension and congestive heart failure (3 blisters x 10 tablets)

How to use

Oral drugs.

Dosage

adjust the dose depending on age and symptom level.

Adults: 5 - 10mg x 1 time/day.

For patients with renal failure: Initially 2.5mg x 1 time/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

When severe hypotension, the patient is in a lying position, low head. Apply supportive measures such as gastric lavage, if necessary, intravenously NaCl isotropic solution to increase the volume of blood flow.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Idatril 5, you may experience unwanted effects (ADR).

Not regular

Reducing red blood cells, hemoglobin, hematocrite and platelets or eosinophilia; Increase bun and creatinin, albuminuria; dizziness, dizziness when standing, headache; Increase GOT, GPT, Al-P, LDH, Bilirubin total; cough, uncomfortable in the throat, fiery on the face, increased serum potassium.

rarely

Nausea, vomiting, discomfort in the stomach and abdominal pain.

Hypersensitivity phenomenon

may be rarely edema due to blood vessels on the face, tongue, bar and larynx causing shortness of breath.

Instructions on how to handle ADR

When the symptoms appear, stop taking the drug immediately. Sometimes there is a rash, itching, then a decrease in the dose or stop taking the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Idatril 5 contraindications in the following cases:

Hypersensitivity to any component of the drug, patients with a history of sensitivity to Imidapril hydrochloride. Sulfonate sodium.

Caution when using

Caution for patients with severe kidney disease, patients with narrowed kidney stenosis on both sides.

Note that patients may have excessive and transient hypotension at the beginning of treatment.

Need to start with low doses and closely monitor during treatment, may gradually increase the dose for the following patients: severe hypertension, dialysis, diuretic treatment (especially those who treat diuretic), need absolute salt diet.

can cause dizziness, dizziness due to reduced blood pressure.

Do not use the drug within 24 hours before surgery.

The drug can cause hypersensitivity signs such as blood vessels in the tongue, subjects and larynx quickly cause shortness of breath. However, this phenomenon rarely occurs. If there are symptoms above, it is necessary to stop taking the drug and use appropriate treatments.

Be cautious when used for the elderly and children.

The ability to drive and operate machinery

The drug can cause dizziness, dizziness due to reducing blood pressure, so be careful when used for drivers and machinery operation.

Pregnancy

Studies on the use of enzyme inhibitors in the second quarter to the third quarter of pregnancy shows that the phenomenon of amniotic fluid, hypotension, kidney failure, hyperkalemia and/or underdeveloped skull in infants, death for infants and pregnancy. In addition, accompanied by amniotic fluid also see spasticity, face deformation.

Therefore, only used for pregnant women when really necessary, the treatment time must be minimized and carefully monitor the status of the fetus and the volume of amniotic fluid.

Breastfeeding period

Rat research shows that the drug is excreted in breast milk, so the mother who is breastfeeding must stop taking the drug during this period or stop breastfeeding when taking the drug.

Drug interaction

Imidapril may increase serum potassium levels during potassium or potassium diuretic, especially in patients with impaired kidney function. In addition, diuretic gums can increase the effect of lowering blood pressure in the early days of using imidapril.

Lithium poisoning has seen abroad in patients using lithium parallel to the angiotensin transferring enzyme inhibitors. Serum lithium concentration must be monitored regularly when used at the same time as Imidapril.

Storage

The temperature does not exceed 30 ° C, avoiding light and moisture.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.