Illixime small otus solution 0.3% hanlim to treat external otitis, chronic otitis media (5ml)

Dosage form Box
Specifications Ofloxacin

Ingredient

Composition information	Content
Ofloxacin	15mg

Uses

Indications

0.3% Illixime drug is indicated in the following cases:

Middle otitis or acute otitis. Ofloxacin's main mechanism is to inhibit DNA gyrase, a bacterial topoisomerase. DNA Gyrase is an enzyme necessary for cloning, copying, repairing and re -combining DNA. This enzyme inhibition leads to bacterial DNA instability and thus killing bacteria cells.

recorded the cross -resistance between ofloxacin and other fluoroquinolone. Overall there is no cross-resistance between ofloxacin and other antibiotic groups such as beta-lactam or aminoglycoside.

Ofloxacin has antibiotics for the following species on vitro and clinically in the treatment of infections in the ear:

Aerobic Gram -positive bacteria: Staphylococcus aureus, Streptococcus pneumoniae.

pharmacokinetic pharmacokinetics

Serum concentration (for patients to open the eardrum and perforation of the eardrum), in the ear fluid and in the mucosa of the middle ear (for patients with perforation of the eardrum) is determined after using small eardrum of Ofloxacin.

In two studies at the usual dose, the low serum ofloxacin concentration in adult patients opened the eardrum with or without ear fluid, after using the small solution of Ofloxacin, 0.3% (4.1ng/ml (n = 3) and 5.4ng/ml (n = 5) respectively). In adults perforation of the eardrum, the maximum serum concentration is 10NG/mL after the small solution of Ofloxacin East solution is 0.3%, ofloxacin is detected in the middle ear mucosa in some adult patients perforation of ear eardrum (11 of 16 people). Ofloxacin concentration in the mucosa between the oscillation in a large range. The measured concentration is from 1.2 to 602mcg/g after small solution ofloxacin solution 0.3%.

ofloxacin concentration is high in the pus epidemic (389–2850mcg/g, n = 13) 30 minutes after taking 0.3% small earloxacin tai solution for patients who are adults with chronic otitis media with chronic pus and perforation of the eardrum. However, the measurement of ofloxacin concentration in pus discharge does not necessarily reflect the contact of the middle ear with ofloxacin.

Before taking Illixime small otus solution 0.3% hanlim to treat external otitis, chronic otitis media (5ml)

How to use

Tai Tai.

Dosage

Specific dose depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? ECG should be monitored because of the risk of extending the QT.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

Notify the doctor with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Illixime 0.3% contraindicated drug in the following cases:

History of hypersensitivity to ofloxacin.

Precautions when using

No data.

Drug interaction

studies on drug interactions have not been done.

Storage

Store in closed boxes at a temperature not exceeding 30 ° C.

Other drugs

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