Imeclor 125 Imexpharm pills treat respiratory infections, urinary tract (12 packs)

Dosage form 12 package box
Specifications Cefaclor

Ingredient

Composition information	Content
Cefaclor	125mg

Uses

Indications

Imeclor 125 mg is indicated for the following cases:

Middle otitis. Learning

cefaclor is a bactericidal antibiotic belonging to the cephalosporin group. The mechanism of action of Cefaclor is to inhibit the synthesis of bacterial cell walls.

Cefaclor has a vitro printing effect on Gram-positive bacteria similar to cefalexin, but has a stronger effect on Gram-negative bacteria, especially with Haemophilus Influenzae and Moraxella Catarrhalis, even with H. Influenzae and M. CatVrhalis producing Beta-Lactamase.

Dynamic pharmacokinetics

cefaclor is well absorbed after drinking. With a dose of 250 mg and 500 mg oral at hunger, the average peak concentration in plasma is about 7 and 13 mcg/ml, achieved after 30 to 60 minutes. Food slowly absorbed, but the total amount of drugs absorbed is unchanged. About 25% Cefaclor binds to plasma proteins.

cefaclor is widely distributed throughout the body; Going through the placenta and excreting into breast milk at low concentrations.

Semi -selling time in plasma from 30 to 60 minutes; This time usually lasts more in people with reduced renal function. If the kidney function is completely lost, the selling time lasts from 2.3 to 2.8 hours. The drug is excreted through the kidneys mainly.

Before taking Imeclor 125 Imexpharm pills treat respiratory infections, urinary tract (12 packs)

How to use

Should drink Imeclor 125 1 hour before meals or 2 hours after meals.

Dosage

Adults: The usual dose for adults is 250 - 500 mg every 8 hours. Do not drink more than 4 g/day.

Children: 20 - 40 mg/kg body weight/24 hours, divided into 3 drinks. Or:

Children over 5 years old: 250 mg/time, 3 times a day.

Children 1 - 5 years old: 125 mg/time, 3 times a day.

Children under 1 year of age: 62.5 mg/time, 3 times a day.

Safety and effectiveness for children under 1 month of age has not been established.

Maximum daily dose in children must not exceed 1.5 g.

Dosage reduction in cases of severe renal failure.

Continue to take additional pills at least 48 to 72 hours after the symptoms are over.

What to do when you forget the dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

What to do when overdose?

Symptoms

Symptoms of overdose may be nausea, vomiting, epigastric pain, diarrhea. The severity of epigastric pain and diarrhea related to the dose. If there are other symptoms, may be caused by allergies, or the effect of another poisoning or the current disease of the patient.

Handling

It is necessary to consider the overdose of many drugs, drug interactions, abnormal pharmacokinetics in patients. No need to wash the stomach, intestines, unless you have taken Cefaclor at a dose of 5 times the normal dose.

Protect the respiratory tract for patients, support ventilation and infusion. Reduce the absorption of drugs by giving activated carbon many times. In many cases, this method is more effective than causing vomiting or gastric lavage.

Side Effects

When taking Imeclor 125 mg, you may experience unwanted effects (ADR).

Common

diarrhea, hyperburgue loves eosin, measles skin rash.

Less.

Nausea, vomiting, itching, urticaria, lymphocytes, leukopenia, neutropenia, genitals, vaginitis, candidiasis infections.

platelet decrease, fake colitis, hepatitis, jaundice, liver enzyme.

Instructions on how to handle ADR

Stop the drug when allergies occur. If serious, conduct supportive treatment (maintain ventilation, oxygen, use adrenalin, intravenous corticosteroid).

Stop treatment if severe diarrhea.

fake colitis:

If mild symptoms: Stop drugs.

Notify the doctor with unwanted effects when using the drug.

Warnings

Contraindicated

Contraindications for cases of hypersensitivity to cephalosporin antibiotics. For patients with hypersensitivity to penicillin antibiotics, it is advisable to consider cross -allergies.

Be cautious when using

Caution for patients with a history of allergies to penicillin because of cross -sensitivity (5 - 10% of cases).

For patients with severe and prolonged diarrhea during treatment with Cefaclor, it is advisable to consider the possibility of fake colitis caused by Clostridium difficile. Because this situation is life -threatening, it is necessary to stop using Cefaclor immediately and take appropriate therapeutic measures.

Prolonged treatment with Cefaclor may increase non -sensitive bacteria.

Be cautious for people with severe impaired renal function, especially when used in combination with kidney toxic antibiotics (aminosid antibiotic groups) or furosemid diuretic, ethacrynic acid.

pregnancy or lactation

Pregnant women

There is no complete research on drug use for pregnant women. Be careful when using and should consider the benefits of the mother and the danger to the fetus.

Women who are breastfeeding

cefaclor excreted breast milk with low concentrations. The impact of the drug on breastfeeding is unknown, so pay attention when children have diarrhea, wasting and rash.

The ability to drive and operate machinery

The drug does not affect the ability to drive and operate machinery.

Drug interaction

simultaneously use Cefaclor and Warfarin rarely increase prothrombin time, causing clinical bleeding or clinical bleeding, especially patients with vitamin K, patients with renal insufficiency. For this patient, should monitor regularly prothrombin and adjust the dose if necessary.

Probenecid increases the concentration of cefaclor in serum.

Cefaclor is simultaneously used with aminoglycosides or Furosemid diuretic, which increases the toxicity of the kidneys.Clinical

subclinical

While doing blood transfusions or testing Coombs test in infants whose mothers used cefaclor before birth, this reaction may be positive for drugs.

Find the urinary glucose with false reducing agents.

Storage

Store at temperatures not more than 30 ° C, avoid moisture and light.

Expiry date: 24 months from the date of production.

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