Insunova 30/70 100iu Mega We Care Drugs Treatment of diabetes (10ml)

Dosage form Box X 10ml
Specifications Insulin Human, Rdna Origin

Ingredient

Composition information	Content
Insulin Human, Rdna Origin	100UI

Uses

indications

Insunova drugs are indicated in the following cases: Treatment of diabetes.

Pharmacokology

The impact of insulin's blood glucose is due to glucose absorption after insulin attached to receptors on muscle and fat cells and inhibit the production of glucose in the liver. The selling time of insulin in the blood is a few minutes.

Therefore, the impact time of an insulin preparation is only determined by absorption characteristics. This process is influenced by a number of factors (such as insulin dose, injection and injection site), which is why it is necessary to consider changes in each patient and between patients.

Dynamic pharmacokinetics

insulin are metabolized in the liver and kidneys, a small amount is metabolized in muscle and adipose tissue. It binds to the receptor on the cell surface, is brought into cells and is then degenerated by the enzyme insulin glutathione transhydrogenase into a chain A and B and by specific intracellular protease enzyme. When Insunova is injected subcutaneously, the starting impact will occur within 30 minutes after the injection, the peak concentration reaches 2 - 8 hours, the effect time is up to 24 hours.

Average of impact process after injection under the Insunova as follows:

Start the impact within 30 minutes.

Maximum impact: from 2 - 8 hours.

Before taking Insunova 30/70 100iu Mega We Care Drugs Treatment of diabetes (10ml)

How to use

Insunova drugs for subcutaneous injection.

Normally, injecting insulin insulin mixes once or twice a day, injected subcutaneously, preferably before meals, when you want to start the impact quickly at the same time with longer impact.

The ideal injection of Insunova, but is not always, is within 30 minutes after the main meal or a snack containing carbohydrates. The injection site should be rotated in an area of the body to avoid lipid dysplasia in diabetics patients, optimal blood sugar control will slow down the process of diabetes complications. Therefore, it is recommended to closely monitor blood glucose.

Do not use insunova for intravenous injection.

Instructions on how to inject:

Insulin injection under the skin. Using the injection technique described in the instructions for using Insupen pen.

Hold the needle under the skin for at least 10 seconds to ensure that the dose is released enough.

After each injection, remove needles and storage insunova pipes in Insupen injection pens without needles. If not, the drug may be leaked, resulting in an incorrect dose adjustment. Medium daily insulin dose to treat diabetes from 0.3 - 1.0 IU/kg depending on the metabolism of each patient and blood sugar control.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose? However, hypoglycemia can develop sequentially in stages:

Mild hypoglycemic stage can be treated by taking glucose or sugar products. Therefore, it is recommended that patients with diabetes always carry some sugar, sweets, biscuits or sugar juice.

The severe hypoglycemic stage that patients may become conscious, can be treated with glucagon (0.5 to 1 mg) intramuscularly or subcutaneously injected by a trained person, or by intravenously by a medical staff. Glucose intravenous injection if the patient does not respond to glucagon within 10 to 15 minutes.

After regaining consciousness, it is recommended that patients eat carbohydrates to prevent recurrence.

What to do when forgetting a dose? In case of forgetting to take the drug, the best way is to measure blood glucose and add an insulin (regular) if the glucose concentration is too high. If not, wait until the next dose at the treatment process.

Side Effects

When using Insunova, you may experience unwanted effects (ADR).

Serious

For other insulin products, in general, hypoglycemia is the most unwanted effect. It may occur if the insulin dose is too high compared to the need. Symptoms of hypoglycemia may be caused by adrenalin release, or by providing incomplete glucose glucose. Hypoglycemia can cause four places to sleep, nightmares or cold sweats that wake the patient at night. With severe hypoglycemia, glucose deficiency on the brain can be stuttered, concentrated, confusion, convulsions, coma, brain damage not recovered and die.Common

Hypoglycemia from mild to medium. Including cold sweat, anxiety, tremor, hunger, tachycardia, headache and stress. When using insulin, common is weight gain.

rarely

Anaphylactic reactions and lipid dysplasia may occur in the injection site, the result of failure when rotating the injection position in an area. Chemicals may occur at the beginning of treatment with insulin. These symptoms are usually temporary.

Instructions on how to handle ADR

Notify the doctor the unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Insunova drugs contraindicated in the following cases:

Hypoglycemia.

Hypersensitivity to human insulin or any ingredients of the drug.

Caution when used

Inadequate use or stop treatment, especially in type 1 diabetes, which can lead to hyperglycemia and diabetic acid ceton infection. Usually the first symptoms of hyperglycemia appear in turn, over hours or days. Including thirst, increasing frequency of urination, nausea, vomiting, drowsiness, dry red skin, dry mouth, loss of appetite as well as acetone smell in the breath.

Do not use overdue insulin printed on packaging.

Should only use the drug tube combined with products compatible with them and to ensure the drug tube works safely and effectively. Insunova is a water -white body, opaque white, containing human insulin. Do not use Insunova without the uniform white color after turning gently. Eliminate abnormal products or scrap according to internal regulations.

insunova contains M - Cresol, which can lead to tube allergic reaction (late hypersensitivity reaction).

Stop taking medicine

Do not stop insulin injections unless the doctor's request. Regularly instruct patients with diabetes how to identify insulin doses needed based on glucose levels at home.

Be cautious when converting insulin

Patients switched to using another type of insulin or another, which should be performed under clinical closely monitoring. Changes in content, brand (manufacturer, type (fast -acting insulin, intermediate impact, prolonged effects, ...), categories (animal -based insulin) may need to change the dose.

Patients switching to insunova or switching from insunova may need to change the normal insulin dose. If necessary, adjustable in the first few days of use or up to a few weeks.

In patients, the control of blood glucose levels has improved significantly, for example by enhancing treatment for insulin, there may be changes in the common warning symptoms of hypoglycemia and need appropriate advice.

There have been an increase in a few patients with hypoglycemic reactions when transferring from animal -based insulin, early warning symptoms of lower hypoglycemia is less obvious or different from previous insulin users.

Changes in dosage needs

may be needed to adjust the dose if the patient enhances physical activity or changes the normal diet. Simultaneous diseases, especially bacterial infections and other symptoms similar to fever, often increase insulin demand. Alcohol can enhance and prolong the hypoglycemic effect of insulin.

The ability to drive and operate machinery

The ability to concentrate and react quickly to the patient may be impaired due to the result of hypoglycemia. Patients need advice to take measures to prevent hypoglycemia while driving. This is especially important in those who are impaired or unaware of the warning signs of hypoglycemia. It is necessary to consider driving ability in these cases.

Pregnancy

There is no restriction on insulin to treat diabetes during pregnancy because insulin does not pass the placenta. When treating diabetes in pregnant women, it is recommended to enhance blood sugar control during pregnancy and even when intended to become pregnant.

Insulin demand usually decreases in the first 3 months of pregnancy and then increases in the middle and the last 3 months of pregnancy.

The period of breastfeeding

after birth, insulin demand quickly returns to the point of pregnancy. There is no restriction on using insulin to treat diabetes in women who are breastfeeding because there is no risk for the baby. Insulin demand decreases during breastfeeding. Monitoring blood sugar at home to avoid the risk of hypoglycemia. However, insulin dose should be reduced.

Interactive drug

Some drugs are known to interact with insulin due to being related to glucose metabolism. Therefore, physicians should pay attention to the interactive capabilities that may occur.

Some drugs that reduce insulin demand: Oral hypoglycemic drugs (OHA), Octeotride, Monoamine Oxidase Enzyme inhibitors (MA MAI), unsatisfactory beta inhibitors, Angiotensin (ACE), Salicylate, alcohol and steroids.

Some drugs that increase insulin demand: Oral contraceptive pills, thiazid diuretics, glucocorticosteroids, thyroid stimulating and sympathetic strength, danazol, ... beta inhibitors can cover symptoms of two blood sugars.

Cavalry

Should only add insulin products, known compounds are compatible. Do not put insulin mixture into intravenous fluids.

Storage

Store in the refrigerator at a temperature of 2 - 8 ° C.

Do not freeze. The chaos can be stored at room temperature (less than 25 ° C) within 6 weeks once the pipe has been put into use. Do not contact heat and direct sunlight.

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