Irbesartan-Am 150mg Meyer-BPC treatment of hypertension, kidney disease (2 blisters x 10 tablets)

Dosage form Box of 2 blisters x 10 tablets
Specifications Irbesartan

Ingredient

Composition information	Content
Irbesartan	150mg

Uses

indications

Irbesartan - AM is indicated in the following cases:

Treatment of primary hypertension. Angiotensin-II. Angiotensin-II receptor selection (AT1) increases plasma resin and angiotensin-II concentration, reducing plasma Aldosterone levels.

High blood pressure: Irbesartan lower blood pressure with minimum changes in heart rate in mice. The decrease in blood pressure depends on the dose of stable stable at dosage over 300mg once/day. Doses of 150-300mg once a day, lowering the bottom blood pressure in the sitting position and measuring in the lying position (meaning 24 hours after the medication) is 8 - 13/5 - 8mmHg (centromonal/diastolic) better than the placebo users.

Hypertension and kidney disease in patients with diabetes type 2: Research "Irbesartan diabetic nephropathy trial = IDNT" shows that Irbesartan reduces the process of kidney disease in patients with chronic renal impairment and proteinuria has appeared. IDNT is a double, random study that has a control of mortality and injury to compare with amlodipine and placebo.

pharmacokinetics

No report.

Before taking Irbesartan-Am 150mg Meyer-BPC treatment of hypertension, kidney disease (2 blisters x 10 tablets)

How to use

Drugs used by oral.

Use 1 time a day, drink with food or not.

Dosage

Starting dose: 150 mg/time/day, depending on the response of the dose blood pressure may increase to 300 mg/day/day or use another anti -hypertension drug. Maximum hypotension effect achieved 4-6 weeks after the beginning of treatment.

No dose adjustment in people with renal impairment.

Patients with dialysis and people over 75 years of age dose: 75 mg/time/day.

Patients with hypertension and type 2 diabetes, use the maintenance dose 300 mg/day/day for the treatment of kidney disease combined.

The combination of drugs with another hypertension medication must be prescribed by a doctor.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Irbesartan - AM, you may experience unwanted effects (ADR).

Side effects reported by Irbesartan are usually mild and transient, including dizziness, headache and hypotension depending on the dose. Hypotension may occur especially in patients with intravascular volume impairment (for example, patients with high dosage diuretics). Impaired renal function, and rare with rash, urticaria, itching, angioedema and liver enzymes may occur. Hyperbonia, muscle pain and joint pain have been reported.

Other side effects have been reported for angiotensin II receptor antagonists including respiratory disorders, back pain, digestive disorders, fatigue and neutropenia. Ly Co Van rarely occurs.

Instructions on how to handle ADR:

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Irbesartan - AM contraindicated in the following cases:

Pregnant and lactating women.

Contraindications related to hydrochlorothiazid.

Severe renal failure (Creatinine clearance

Hypotension, hyperactive blood.

Severe liver failure, biliary cirrhosis and cholestasis.

Be cautious when used

Starting treatment with hypertension may cause symptomic hypotension in patients with intravascular volume impairment or sodium decrease, for example, patients use strong diuretic therapy or fertilizer. This decrease in the volume of epidemic should be adjusted before taking Irbesartan or the starting dose is lower.

In general, in patients with blood vessel tone and renal function depend mainly on the activity of the Renin-Anotensin-Aldosteron system (such as severe congestive heart failure or kidney disease, including kidney stenosis), treatment with transferred inhibitors or Angiotensin II receptor antagonists are drugs that can affect this system, which can cause blood pressure, hypertension, hyperurize, hyperur Acute renal failure. Like all other antihypertensive drugs, excessive hypotension in patients with ischemic heart disease can lead to myocardial blood or stroke.

The ability to drive and operate machinery

When driving and operating machinery, it should be noted that dizziness or fatigue may occur during treatment.

Pregnancy

Do not take medicine for pregnant women.

Breastfeeding period

Do not take medicine for breastfeeding women.

Interaction

Diuretics and other hypertension drugs: may increase the hypotension effect of Irbesartan.

Potassium supplements and potassium -saving diuretic supplements: can lead to increased serum potassium levels.

Lithi: Need to carefully monitor serum lithium concentration if this combination is necessary.

Non -steroid anti -inflammatory drugs: reduce hypertension.

There is no significant pharmacokinetic interaction (or pharmaceutical) in studies on interactive with hydrochlorothiazid, digoxin, warfarin and nifedipine. Based on in vitro data, there is no possibility of interacting with drugs that their metabolism depends on Cytochrom P450 ISOENZYM 1A1, 1A2, 2A6, 2B6, 2D6, 2E1 or 3A4.

Storage

Store in a cool, dry place, avoid direct light, under 30 ° C.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.