Ivermectin 6mg tablets A.T supports the treatment of parasitic infections (1 blister x 4 tablets)

Dosage form Box of 1 blister x 4 tablets
Specifications Ivermectin

Ingredient

Composition information	Content
Ivermectin	6mg

Uses

indications

Ivermectin 6mg drug is indicated for treatment of parasitic infections for adults and children> 5 years old (weight ≥ 15 kg), including:

Worm disease is only onchocerca. Ozzardi. Streptomyces Avermitilis. Ivermectin has a broad activity spectrum on round worms such as e -worms, hair worms, needle worms, roundworms, hookworms and worms. However, the drug does not work on liver fluke and tapeworms.

The drug has a direct impact, immobile and eliminating larvae through the lymphatic lymphatic. Ivermectin stimulates the secretion of neurotransmitters is Gama acid - Amino Butyric (GABA).

In sensitive worms, the drug affects by enhancing the release of gaba after the Sinap of the neuromuscular joint, causing the worm to be paralyzed, especially killing the larvae moving into internal organs such as skin, eyes, liver, central nervous system, lung, muscular, even myocardial.

The drug is relatively safe, the unwanted effects are mainly due to the toxin of the worms secreted after decomposition, such as itching, dizziness, dizziness, muscle aches, joint pain, hypotension.

Pharmacokinetics

absorption

Unknown the absolute bioavailability of the drug after taken. Time to reach the peak concentration in plasma is about 4 hours, when using iVeMectin in a alcohol solution, the peak concentration doubles, the bioavailability of the solution is only 60%.

Distribution

About 93% linked to plasma proteins.

Metabolism

Hydrolyzed and reduced methyl in the liver.

Elimination

Ivermectin is excreted through bile and eliminates almost only through stool. Less than 1% of the dose is discharged through urine.

Before taking Ivermectin 6mg tablets A.T supports the treatment of parasitic infections (1 blister x 4 tablets)

How to use

Ivermectin 6mg oral drug.

Take Ivermectin with water at hunger, avoid eating within 2 hours before and after taking the drug.

Dosage

Adults, children ≥ 15 kg

Worm disease is only onchocerca: taking a single dose of 0.15 mg/kg. Higher doses will increase the harmful reaction without increasing the effectiveness of treatment. It is necessary to re -treat the same dose as above 3 - 12 months until there are no more symptoms.

Eelworm disease in Strongyloides Stercoralis: Use a single dose of 0.2 mg/kg with a stool test. Or you can use the dose of 0.2 mg/kg/day, for 2 days.

Infection of roundworms due to Ascaris Lumbricoides: Use 1 single dose 0.15 - 0.2 mg/kg.

Larvae move on skin by Ancylostoma Brazilense: 0.2 mg/kg/day, for 1-2 days.

Worm infection is only caused by Mansonella Ozzardi: using a single dose of 0.2 mg/kg.

Worm infection is only caused by Mansonella Streptocerca: using a single dose of 0.15 mg/kg.

Worms infection only due to Wuchereria bancrofti: using a single dose of 0.15 mg/kg in combination with albendazole.

Ivermectin's recommended dose is based on body weight:

Dosage as prescribed 0.15 mg/kg

gravity (kg) The only dose of oral drink mg/kg Body (kg) The only drink mg/kg Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose? Other unwanted effects include seizures, air conditioning, shortness of breath, abdominal pain, abdominal pain and urticaria.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

When side effects, infusion and electrolytes, respiratory aids (oxygen and artificial respiration if needed). Using hypertension if hypotension. Causing vomiting or gastric wash as soon as possible. After that, use bleach and other anti -toxic measures if needed to prevent the absorption of more drugs into the body.

What to do when you forget 1 dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Ivermectin 6mg, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Osteoarthritis: joint pain, epidemic inflammation.

Lymph nodes: enlarged and lymph nodes in the armpits, neck, groin.

Skin: itching, skin reactions such as edema, nodules, pustules, skin rash, urticaria.

Systemic: Fever, edema (face, peripheral).

Cardiovascular: Hypotenary pressure vertical, tachycardia.

Uncommon, 1/1000

Central nerve: headache.

Peripheral nerve: muscle pain.

Instructions on how to handle ADR

Ivermectin can cause skin reactions and systemic reactions to different levels (Mazzotti reaction) and eye reactions in patients with worms only onchocerca.

These reactions may be a result of allergic response and inflammation caused by dead larvae. It is possible to treat these reactions by taking analgesics, antihistamine or corticosteroid injection as soon as the symptoms appear. Dosage depending on the degree of the reaction.

When hypotension is standing, orally, lying, lying, intravenous salt water or corticosteroid injection.

It should be remembered that iVERMECTIN does not kill the adult onchocerca parasites, thus regularly monitoring and re -treatment is necessary.

Notice immediately to the doctor or pharmacist unwanted effects when using the drug.

Warnings

Contraindicated

Ivermectin 6mg contraindications in the following cases:

Hypersensitivity to Ivermectin or a certain ingredient of the drug.

Diseases accompanied by disorders of cerebrovascular fence, meningitis.

Be cautious when used

The drug contains lactose. Patients with rare genetic disorders such as galactose intolerance, lapp lactase deficiency or Glucose - Galactose absorption disorders do not take this drug.

Avoid for children under 5 years old, pregnant or nursing women.

When used for treatment for worms, only onchocerca dermatitis increases the reaction, there may be more harmful reactions, especially edema and make the condition worse.

The ability to drive and operate machinery

In the treatment dose, the drug does not affect the ability to drive and operate machinery. However, note that dizziness may occur during treatment.

Pregnancy

Avoid drugs for pregnant women.

Breastfeeding period

Avoid taking medicine for breastfeeding women.

Drug interaction

Not notice of harmful drug interactions, but in terms of theoretical, the drug can increase the effects of GABA receptors stimulants.

Storage

Store in a dry place, avoid light, temperature not exceeding 300C.

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