Kalimate powder 5g dopharma treatment of hyperboly in the blood due to renal failure (5g x 30 packs)

Dosage form 30 package box
Specifications Calcium polystyrene sulfonate

Ingredient

Thành phần cho 5g

Composition informationContent
Calcium polystyrene sulfonate5g

Uses

indications

Kalimate 5G drug is indicated in cases of hyperkalemia due to acute or chronic renal failure.

Pharmacokological

After oral or rectal use, calcium ions of calcium polystyren sulfonate will be exchanged with potassium ions in the intestine, especially in the colon, then the drug is eliminated in the form of polystyren sulfonate resin in the fertilizer.

Next, potassium in the gastrointestinal tract will be eliminated from the body. Calcium Polystyrene sulfonate prepared in preparation contains 7.0 - 9.0 calcium, 1 gram of exchange preparations 53 - 71mg (1.36 - 1.82Meq/g) Potassium in vitro (KCl solution).

When using calcium polystyrene sulfonate 15 - 30g/day for patients with renal impairment (adults), blood potassium concentration decreases by 1MEQ/l.

Unlike sodium plastic, calcium polystyrene sulfonate does not increase sodium and blood phosphate and does not lower blood calcium.

Because calcium polystyrene sulfonate is calcium plastic, which can be used for patients with limited sodium intake. In addition, there is no risk of edema, hypertension or heart failure caused by sodium.

pharmacokinetic pharmacokinetics

Preparations in general are not absorbed. However, animal research shows that sub -fertilizers smaller than 5 μm can be absorbed through the mucosa and accumulated in the endothelium system.

Before taking Kalimate powder 5g dopharma treatment of hyperboly in the blood due to renal failure (5g x 30 packs)

How to use

Kalimate 5G drugs for oral or rectal sugar.

Dosage

Adults, including the elderly

Oral

by oral:

  • The usual dose is 15 g of three or four times a day.
  • Often used for patients with vomiting or have above gastrointestinal problems, including the case of intestinal paralysis or it can be used simultaneously with oral route to achieve faster results. Request to hold drugs in the rectum for at least 9 hours.

    If the chaos flows out, the hip should be highly high, or put the patient sitting in a knee-chest (knee-chest position). After the time of preserving the necessary drug, it is necessary to eliminate the drug from the rectum. Especially in patients with a history of difficulty eliminating, should use the method of removing the drug from the digestive tract.

    Children

    Oral

    by oral:

  • The appropriate initial dose is 1g/kg of body weight every day divided into several times, in case of acute hyperkalemia.
  • The appropriate initial dose is 1g/kg of body weight every day divided into several times, in case of acute hyperkalemia. Warmed to body temperature. Request keeping the drug in the rectum for at least 9 hours. If the chaos flows out, the hip should be highly high, or the patient is sitting in a pillow - chest position (Knee -chest position).

    After the time of preserving the necessary drug, it is necessary to eliminate the drug from the rectum. Especially in patients with a history of difficulty eliminating, should use the method of removing the drug from the digestive tract.

    Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

    What to do when overdose? It can lead to serious consequences of apnea. Manifestations of hypokalemia or hypercalcemia on electrocardiograms, can be arrhythmia.

    Handling: Use appropriate measures to balance electrolytes (potassium, calcium). The drug is from the gastrointestinal tract by taking the enema or the indent.

    What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

    • Side Effects

    When using Kalimate 5G, you may experience unwanted effects (ADR).

    Disorders of metabolism and nutrition:

  • Regarding pharmacological effects, using drugs can lead to hypokalemia and hypercalcemia, and clinical manifestations.
  • Cases of reduced blood magnesium have been reported.
  • Hypercalcemia has been reported in dialysis patients using calcium polystyrene sulfonate, and sometimes in patients with chronic renal failure. Many patients with chronic renal impairment have low blood calcium and high blood phosphate, but some people cannot be tested in advance, showing a sudden increase in blood calcium concentration after high levels of calcium polystyren sulfonate. The risks emphasize the need for adequate biochemical control.

    • Gastrointestinal disorders:

  • Stomach uncomfortable, anorexia, nausea, vomiting, constipation and sometimes diarrhea can occur. Division after use by rectum, especially in children and stomach foreign objects after drinking have been reported. The gastrointestinal stenosis and intestinal obstruction have also been reported, possibly due to pathology or improperly dilution.
  • Gastrointestinal anemia, ischemic colitis, stomach ulcer or necrotic ulcer, which can lead to a report that has been reported, some cases of death. Most cases have been reported to the use of drugs simultaneously with Sorbitol.

    • Respiratory, chest and mediastinum disorders:

  • Some cases of acute bronchitis and/or bronchitis - lungs due to inhalation of calcium polystyren sulfonate calcium beads have been described.

    • Instructions on how to handle ADR

    When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

    Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    Contraindicated

    Kalimate 5g drug contraindicated in the following cases:

  • Patients with potassium concentration in plasma below 5 mmol/liter.
  • Cases related to hypercalcemia (e.g. hyperthyroidism, multiple marrow, sarcoidosis or metastatic cancer).
  • History of hypersensitivity to polystyrene sulfonate plastic.
  • Concluded intestinal disease.
  • Do not take oral medication for infants and contraindicated in infants to reduce bowel motility (after surgery or by drug).

    • Precautions when using

    Caution should be used when using Kalimate 5G Central 2 30 packs on the following patients:

  • Suspected constipation (due to the risk of intestinal obstruction or perforation).
  • Gastrointestinal stenosis (due to the risk of intestinal obstruction or perforation).
  • Gastrointestinal ulcer (due to worsening symptoms).
  • hyperthyroidism (blood calcium levels may increase due to ion exchange).

    • Multivita (blood calcium concentration may increase due to ion exchange).

    Special prudence:

  • There may be a risk of intestinal obstruction or perforation when taking the drug. If any abnormalities occur for example, severe constipation, prolonged abdominal pain, vomiting ... should stop the drug and have appropriate treatment therapies.

    • Patients should be instructed to monitor stool and notify the doctor if constipation is accompanied by obvious symptoms such as abdominal pain, abdominal tension, vomiting, etc.

    Need to monitor potassium and blood calcium concentration regularly when taking the drug to avoid overdose.

    If any abnormalities occur, it is necessary to apply appropriate measures such as reducing the dose or stopping drugs.

    Caution at use:

    Oral

    :

  • To avoid accumulating drugs in the gastrointestinal tract when taken, monitoring to avoid constipation.

    • Rectal Road:

  • Use the calcium polystyrene sulfonate with sorbitol rectal sugar that can cause gut and colon necrosis.
  • To avoid keeping the drug in the rectum, the drug must be eliminated. Especially in patients with a history of difficulty eliminating, should use the method of removing the drug from the digestive tract.

    • In elderly patients: Using drugs in large doses that can cause constipation or closing fertilizer.

    The ability to drive and operate machinery

    does not affect the ability to drive and operate machinery.

    Pregnancy

    Not enough data on the use of calcium polystyren sulfonate for pregnant women.

    Breastfeeding period

    Not enough data on the use of calcium polystyrene sulfonate in nursing women.

    Medicinal interaction

    Digitalis (Digoxin) preparations: Can increase the toxicity of digitalis on the heart due to the hypotension of calcium polystyrene sulfonate.

    antacids and laxatives that contain aluminum, magnesi and calcium (aluminum hydroxyd gel anhydrous gel, magnesium hydroxyd, calcium carbonate ...): Cation exchange effectiveness of calcium polystyren sulfonate can be reduced, using Calcium Polystyren Sulfonate with drugs that can cause alkaline metabolism due to the inhibition gut.

    Lithi: can reduce lithium absorption.

    levothyroxin: may reduce the absorption of levothyroxin.

    Cation agents: may reduce the effectiveness of potassium exchange of calcium polystyrene sulfonate.

    Storage

    In a cool dry place, avoid light, temperature below 30 ° C.

    Other drugs

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