Kaltatri Phil medicine for kidney dysplasia, hyperpigonomical gland (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Alfacalcidol

Ingredient

Composition information	Content
Alfacalcidol	0.5mcg

Uses

indications

Kaltatri drugs are indicated in the following cases:

Kidney bone dysplasia. bone. After absorbing, alfacalcidol was quickly hydroxylized in the liver, although this enzyme is widely distributed in the body's tissues. Alfacalcidol (1 A-Hydroxy Vitamin D3) rapidly converts the liver into 1.25-dihydroxy vitamin D3, acting as a regulation of calcium and phosphate metabolic.

Thanks to this rapid transformation, the treatment benefits of alfacalcidol are almost like 1.25-dihydroxy vitamin D3. The main effect is to increase the circulatory concentration of 1.25-dihydroxy vitamin D3, thus increasing the absorption of the intestines of calcium and phosphate, promoting bone mineralization, regulating the levels of the hormones in the plasma as well as reducing bone and muscle pain.

Dynamic pharmacokinetics

alfacalcidol absorbs well according to the gastrointestinal tract. The presence of bile necessary for absorption, absorption can be reduced in patients with reduced fat absorption.

alfacalcidol transports in the blood connected to a-globulin. Alfacalcidol has a fast and short -selling time.

alfacalcidol quickly metabolizes in the liver into Calcitriol. Vitamin D compounds and mainly eliminated metabolites in bile and feces, only a small amount present in the urine.

Before taking Kaltatri Phil medicine for kidney dysplasia, hyperpigonomical gland (10 blisters x 10 tablets)

How to use

Kaltatri drugs for oral use.

Dosage

Starting dose:

Except for osteoporosis:

Adults: 1 µg/day. Customs.

The dose is then adjusted according to biochemical response to avoid hypercalcemia. The dose of alfacalcidol can increase by 0.25 - 0.5 µg/day. Most adults respond at 1 - 2 µg/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

Symptoms

Manifestations of hypercalcemia: fatigue, dizziness, nausea, vomiting, dry mouth, muscle pain, bone pain, joint pain, itching or chest drum.

Treatment

should stop treating alfacalcidol when hypercalcemia. Hypercalcemia may need supportive treatment, intravenous fluid, and if necessary, add diuretics or corticosteroids.

In case of acute poisoning, it is recommended to be treated with stomach and/or mineral oils to reduce the absorption and increase excretion through feces.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

In general, side effects associated with hypercalcemia and in the case of kidney failure, hyperglycemia may occur.

Other undesirable effects: itching, rash, urticaria.

Notify the doctor with unwanted effects when taking the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Kaltatri drugs contraindicated in the following cases:

Hypersensitivity to alfacalcidol or any ingredients of the drug.

Be cautious when using

Alfacalcidol increases the absorption of calcium and phosphate in the intestine, their serum concentration should be monitored, especially in patients with renal impairment.

Need to monitor calcium, phosphate, alkaline phosphate, magnesium and creatinine periodically periodically as well as other necessary biochemical parameters.

If a hypercalcemia occurs or hypercalcemia, it can be adjusted quickly by stopping treatment until the plasma calcium concentration returns to normal.

then alfacalcidol may start again with 2 doses of the last dose used or according to the patient's response.

Be cautious when using alfacalcidol in patients with hypercalcium, especially in patients with a history of kidney stones.

The effect of the drug on the ability to drive and operate machinery

This drug is not or negligible on the ability to drive and operate machinery.

Use drugs for women during pregnancy and lactation

Pregnant women

There is no adequate data on the use of alfacalcidol in pregnant women. Be cautious when used for pregnant women because of hypercalcemia during pregnancy can cause congenital disorders for babies.

breastfeeding women

Although it has not been determined, the amount of 1.25-dihydroxyvitamin d may increase in the milk of the mother who is breastfeeding treated with alfacalcidol. This may affect the child's calcium metabolism.

Interactive drug

Hyperculia hypercalcemia in patients using cardiac glycosides can cause arrhythmia. Therefore, patients with simultaneous use of cardiac glycosides and alfacalcidol should be closely monitored.

When using Barbiturate or anti -convulsive drugs, Alfacalcidol should be increased to achieve the necessary effect.

Used with mineral oil (long -term use), cholestyramin, colestipol, sufacrat, or large amounts of aluminum in antacids can reduce the absorption of Alfacalcidol.

The risk of increasing calcium hypercalcemia in patients using preparations containing calcium or thiazid diuretics with alfacalcidol.

Do not share alfacalcidol with vitamin D or substances of vitamin D due to its ability to increase the effect and increase the risk of hypercalcemia.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

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