Kentax Detapharm skin cream for strabismus treatment, tinea versicolor, sparkling, interstitial mushrooms (5g)

Dosage form Cream
Specifications Tube
Ingredient Ketoconazole

Ingredient

Thành phần cho 5g

Composition information	Content
Ketoconazole	0.1g

Uses

indications

Kentax drugs used to apply skin for treatment:

Treatment of strabismus (ringworm), tinea versicolor, lazy, interstitial mushrooms, nail mushrooms, hair mushrooms. In the skin. Like other anti -fungal Azol conductors, Ketoconazole inhibits the activity of cytochrom P450 is an enzyme system needed for methyl reduction of 14 alpha - methyl - sterol (for example, lanosterol) to Ergosterol as the main sterol of fungal cell membranes, the amount of Ergosterol reduced will change the permeability and function of the cell membrane.

Ketoconazol's fungal killing effects at high concentrations can be the direct chemical effect of the drug on the fungal cell membrane. With Candida albicans, Azol antifungal drugs inhibit the transformation from the form of spores of shoots into fibers capable of penetrating disease.

pharmacokinetics

When absorbed into ketoconazole blood, distributed into inflamed joint fluids, saliva, molasses, urine, milk, earwax with mucus, stool, tendon, skin, soft tissue, testicular (small amount), the drug can not pass through the blood barrier - the brain should only reach an insignificant amount in the cerebrospinal fluid.

The ratio of binding with plasma proteins is 84 - 99%, mainly with albumin.

Plasma concentration in a 2 -phase -style form, half a lifetime is approximately 2 hours in the first phase and approximately 8 hours in the last phase.

Ketoconazole metabolizes partially in the liver, creating non -activity derivatives through oxidation and holes of imidazol and piperazine, the process of O -DEL - DEALKIL HUMILITY. The main path to eliminate drugs and its metabolites is through the bile and then into the feces.

When applied on the spot, ketoconazole is not absorbed into the blood, only acting on the contact surface of the drug. Ketoconazole penetrates through cell membranes and inhibits the growth of pathogenic fungi.

Ketoconazole does not produce a concentration that can be detected in the blood when used on the spot.

Before taking Kentax Detapharm skin cream for strabismus treatment, tinea versicolor, sparkling, interstitial mushrooms (5g)

How to use

topical drugs.

Dosage

used on the spot

Candida mushrooms in the skin, tinea versicolor, body skin or thigh skin fungus

Apply 1 time/day for 2 weeks.

seborrheic dermatitis

Apply 2 times/day for 4 weeks or until the disease is cured.

Foot skin mushrooms

Apply 1 time/day for 2 weeks.

For strabismus, darkness, tinea versicolor, mushroom mushrooms, mushrooms in the body in general:

Apply the drug 1 or 2 times a day. To achieve high efficiency, it is necessary to apply all over the damaged skin.

When using Kentax, the symptoms will reduce significantly in the first 2-3 days, but most cases after only one application show signs of decrease. To avoid recurrence should apply continuously for at least 2 weeks and when necessary, the process can last up to 4 weeks.

After 2 weeks continuously if the clinical results do not see clearly, request to review the diagnosis.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

When applying kentax cream on a large -scale skin area, the absorption of ketoconazole into the blood has not been detected at the level of concentration of 5ng/ml in the blood for 72 hours.

At this extremely low absorption concentration does not raise the problem of systemic poisoning because Kentax cream contains 2%ketoconazole.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Kentax, you may experience unwanted effects (ADR).

Side effects rarely occur (accounting for about 2% of Ketoconazole users) including irritation, itching, stinging or feeling like an ant.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Kentax drug is contraindicated for people who are allergic to ketoconazol.

Be cautious when using

Do not use Kentax cream to look into the eye.

After applying with irritation or allergies, it should be stopped.

Read the instructions carefully and use before use. If you need more information, please consult your doctor.

The ability to drive and operate machinery

drugs can be used for people when driving and operating machinery.

Pregnancy

should not be used for pregnant women, only used when really necessary. Consult your doctor before use.

The period of breastfeeding

should not be used for women who are breastfeeding, only used when they are really necessary. Consult your doctor before use.

Drug interaction

Ketoconazole's drug interaction with some other drugs only encountered when Ketoconazole was absorbed into the bloodstream, however, Kentax applied the skin, almost no absorption into the blood, so the case of drug interactions related to Kentax has not been reported.

Storage

Leave in a dry place, the temperature does not exceed 300C, avoid direct light.

Other drugs

Disclaimer

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