Kesera 750mg Korea Pharma tablets relieve pain due to sprains, muscle tension, injury (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Methocarbamol

Ingredient

Composition information	Content
Methocarbamol	750mg

Uses

Indications

Kesera 750mg drug is indicated in the following cases:

Treatment of muscle tension symptoms, especially lumbar pain (acute back back pain).

Methocarbamol is a muscle relaxant that works on the center. The muscle relaxation effect of the drug is due to inhibition of multi -refigant reflexes in the spinal cord and centers under the shell.

In the treatment dose, methocarbamol does not affect the force field and physiological contraction of the skeletal muscle as well as the movement of the muscles that are not muscle pattern and does not affect the end movement of the muscle mass.

pharmacokinetics

After drinking, methocarbamol is absorbed quickly and completely. It is possible to detect the active ingredient in the blood for 10 minutes after drinking and reach the peak concentration in the blood after 30-60 minutes.

Semi -cancellation time in plasma is 2 hours. Methocarbamol and its two metabolites bind to glucuronic acid and sulfuric acid and are almost completely excreted through the kidneys. About half of the dose is excreted into the urine for 4 hours, only a small part of the drug is eliminated in the form of unchanged methocarbamol.

Patients with renal failure

The clearance of methocarbamol in patients with kidney failure is maintained by a decrease of about 40% compared to normal people, although the average selling time of both groups is the same (equivalent to 1.2 hours compared to 1.1 hours).

Patients with liver failure.

In patients with secondary cirrhosis due to alcoholism, the total total clearance of methocarbamol is reduced by about 70% compared to normal people (11.9l/hour), and the average emission time increases by about 3.4 hours. The ratio of methocarbamol links to plasma proteins decreased by 40 to 45% compared to 46 to 50% of normal people of the same age and weight.

Before taking Kesera 750mg Korea Pharma tablets relieve pain due to sprains, muscle tension, injury (10 blisters x 10 tablets)

How to use

Oral drugs.

Dosage

Big people

The recommended dose for adults is 1500mg methocarbamol x 3 times a day.

When starting treatment, the recommended dose is 1500mg methocarbamol x 4 times a day.

In serious cases, up to 7500mg of methocarbamol can be used daily.

Treatment time depends on the symptoms caused by muscle tension, but not more than 30 days.

Pediatric patients

The safety and effectiveness of methocarbamol in children and adolescents have not been set up.

Elderly patients

half of the maximum or less dose may be sufficient for treatment.

Patients with liver failure

In patients with chronic liver disease, the sale time of the drug may last. Therefore, it is necessary to consider increasing the gap between the doses.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? Methocarbamol overdose often occur in case of alcohol or other central nervous system inhibitors and include the following symptoms: nausea, drowsiness, blurred vision, lower blood pressure, convulsions and coma.

After taking 22.5 to 50g methocarbamol with suicide intentions, two patients were drowsy, but had completely recovered within 24 hours.

In medical documents about 3 deaths when the patient uses more methocarbamol after taking a large amount of alcohol (2 cases) or using opium (1 case) with the intention of suicide.

Overdose of drugs includes gastric wash, symptomatic treatment and monitoring essential functions. Benefits of dialysis in overdose of drugs have not been established.

What to do when forgetting a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Kesera 750mg, you may experience unwanted effects (ADR).

The frequency of unwanted effects - If the relevant data is given in this document - determined by the following conventions:

Very common (≥ 1/10).

Common (

Less (1/1 000 to

Rare (≥ 1/10 000 to

Very rare (≥ 1/10000).

unknown (frequency indispensable from available data).

Infections and poisoning

Rare: conjunctivitis.

immune system disorders

Very rare: Anaphylactic reaction.

Metabolic and nutrition disorders

Very rare: anorexia.

Mental disorders

Very rare: restlessness, anxiety, confusion.

Nervous system disorders.

Rare: headache, dizziness, mouth with metal flavor.

Very rare: fainting, vibrating eyeball, dizziness, tremor, convulsions.

Unknown: Draying.

Eye disorders

Very rare: vision impairment.

Heart disorders

Very rare: arrhythmia.

circuit disorders

Rare: Low blood pressure.

Very rare: hot burning.

Respiratory disorders, chest and mediastinum

Rare: stuffy nose.

Gastrointestinal disorders

Very rare: nausea, vomiting.

Skin and subcutaneous skin disorders

Rare: Evana, itching, rash, urticaria.

Common disorders and at the position of

Rare: Fever.

Instructions on how to handle ADR

Reporting suspected side effects after circulation is very important. This allows to continue monitoring the benefits/risks of the drug. Health workers must report any suspected side effects on the National Report Center.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Kesera 750mg contraindications in the following cases:

Hypersensitivity to methocarbamol or any ingredients of the drug.

Money for coma, coma, brain damage, central nervous system disorders (CNS), muscle weakness, epilepsy.

Precautions when using

should be carefully used methocarbamol in patients with impaired renal or liver function.

Patients should be informed that drinking alcohol during treatment with methocarbamol or used in combination with substances that work on other concentration may increase the effect of the drug.

affect tests

Methocarbamol can cause many colors in hydroxyindolacetic acid screening tests (5 - HIAA) using nitrosoaphthol reagents and vanillylmandelic acid screening tests (MMA) in urine by gitlow method.

The ability to drive and operate machinery

Methocarbamol has a moderate impact on the ability to drive and operate machinery because methocarbamol can cause dizziness or drowsiness, especially if used with other drugs that cause other drowsiness.

Methocarbamol's undesirable effects can affect the ability to drive and operate the patient's machines.

Pregnancy

There is no experience in using methocarbamol during pregnancy. Animal studies have not established the use of methocarbamol safely with the effects on pregnancy, the development of embryo/fetal embryos, reproduction and postpartum development. The potential risk for humans is not known. Therefore, methocarbamol should not be used during pregnancy.

Breastfeeding period

It is not known whether methocarbamol or its metabolites can be secreted into breast milk. Methocarbamol or its metabolites are secreted into breast milk. Therefore, methocarbamol should not be used for breastfeeding women.

Drug interaction

simultaneously use methocarbamol with drugs that act on the central nervous system such as barbiturat, opioids and appetite inhibitors that can increase the effects of all drugs.

methocarbamol may increase the effects of anti -cholinergic drugs, such as atropine and some mental drugs.

Using methocarbamol along with alcohol can increase the effect of the drug.

methocarbamol may inhibit the effects of pyridostigmin bromid. Therefore, do not use methocarbamol in patients with myasthenia gravis who are using pyridostigmin.

Storage

Store in closed packaging, avoid light, avoid moisture, temperature below 30 ° C.

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