Kirby 300mg hard capsules are achieved to treat phlegm cough, bronchitis (6 blisters x 10 tablets)

Dosage form Box of 6 blisters x 10 tablets
Specifications Erdosteine

Ingredient

Composition information	Content
Erdosteine	300mg

Uses

Indications

Kirby drug indications for treatment in the following cases:

phlegm. Erdostein is a pharmaceutical, after converting the group to create a freelance, the drug becomes active.

The effect of erdostine is due to the opening of the disulfid of the bronchial mucoprotein.

Erdostein also prevents bacterial adhesion on epithelial cells.

Because there is a free thiol group in active metabolites, Erdostein has significant antioxidant effects, reflected in both In vitro and In Vivo research.

pharmacokinetic

absorption

Erdostein absorbs quickly after drinking and quickly metabolizes the liver into the metabolic substance with the activity of N-Tiodiglycolyl-Homocystein (MI).

After taking 300mg, the peak concentration of Erdostine (cmax) is 1.26 ± 0.23 µg/ml achieved after 1.18 ± 0.26 hours (TMAX), while M1 has cmax 3.46 µg/ml and Tmax 1.48 hours.

The plasma concentration of Erdostine increases depends on the dose. The plasma concentration of M1 also increases, but not as linear like the original Erdostein.

The absorption does not depend on food.

distribution

In animal research, Erdostein is distributed mainly into the kidneys, bones, spinal cord and liver.

Erodostein's pharmacological concentration and M1 metabolites are found in alveolar washing fluids. Erdostine is attached to plasma proteins about 64.5% (50 - 86%).

Elimination

Erdostin and m1 semi -waste time is 1.46 ± 0.60 hours and 1.62 ± 0.59 hours. In urine, only M1 and Sulphat found, excreted through negligible fertilizer.

There is no accumulation or change of metabolism of Erdostein and M1 after taking the dose of 600mg and 900mg in 8 days.

The influence of age

Age does not affect Erdostin's pharmacokinetics.

Before taking Kirby 300mg hard capsules are achieved to treat phlegm cough, bronchitis (6 blisters x 10 tablets)

How to use

oral medication, must take whole capsules with water.

Dosage

Elderly and adults over 18 years old: 300mg x 2 times/day, for up to 10 days.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose?

When an overdose occurs, symptomatic treatment should be treated and applied common supportive measures.

Gastric lavage may be useful, then monitor patients.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Kirby often has unwanted effects (ADR) such as:

Common, 1/100 ≤ ADR

Digestive: epigastric pain.

Neurological: headache If you want to be different, it is necessary to closely monitor and recommend the patient to notify the doctor with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Kirby drugs contraindicated in the following cases:

Hypersensitivity to Erdostein or any ingredients of the drug. Cystathionin-Synthetase.

Precautions when using

do not see an increase in unwanted effects when using Erdostein in mild liver failure patients, but should not be used in excess of the dose of 300 mg/day.

Warning and caution related to excipients:

Kirby contains lactose. Patients with rare genetic diseases with galactose tolerance, Lapp Lactase deficiency or glucose absorption disorders - Galactose should not be used.

Using drugs for women during pregnancy and lactation

Inexperienced in using Erdostein on pregnant and lactating women, so it is not recommended to use drugs for this group of patients.

The effect of drugs on driving and operating machinery

Erdostin has a small or negligible influence on the ability to drive and operate machinery.

Medicinal interaction

Medicinal interaction may affect the activity of the drug or cause side effects.

Patients should notify the doctor or pharmacist a list of the drugs and functional foods you are using. Do not use or increase or decrease the dose of the drug without the guidance of a doctor.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.