L-Tyrox 100 Davipharm treat hypothyroidism syndrome (10 blisters x 10 tablets)

6 - 12 years: 100 - 150microgam or 4 - 5microgam/kg/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Symptoms

Causes a state of metabolic increase similar to endogenous armor poisoning. Signs and symptoms are as follows: Losing weight, increasing appetite, hitting chest drums, restlessness, diarrhea, abdominal spasms, sweating, rapid growth, hypertension, arrhythmia, vibration, insomnia, fear of heat, fever, menstrual disorders. Symptoms are not always clear, maybe many days after taking medicine to appear.

Handling

levothyroxin should be reduced or temporarily suspended if signs and symptoms of overdose appear. Extremely acute, symptomatic treatment and immediate support. The purpose of treatment is to reduce the absorption in the gastrointestinal tract and fight the effect on the central and peripheral nervous systems, mainly the effects of increasing sympathetic activity.

Can wash stomach immediately or vomit without other contraindications (coma, convulsions, vomiting reflexes). Cholestyramin or activated carbon is also used to reduce the absorption of levothyroxin. Give oxygen and maintain ventilation if needed. Use beta - adrenergic blockers for example propranolol to prevent many effects increasing sympathetic activity. Propranolol intravenous injection 1 - 3mg/10 minutes or taking 80 - 160mg/day especially without contraindications.

Can use heart glycosides if congestive heart failure appears. It is necessary to take measures to control fever, hypoglycemia, dehydration when needed. Glucocorticoids should be used to inhibit the conversion from T4 to T3. Because T4 bonds a lot of protein, very few drugs are excluded by fertilizer.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Precautions when using

very cautious when used for people with cardiovascular disease and hypertension. The chest pain appears and other cardiovascular diseases need to reduce the dose.

People with diabetes or diabetes or adrenal diabetes, when treating levothyroxin, will increase the symptoms. Adjusting the appropriate treatment measures in these hormonal diseases is essential. Sealed coma must be used with glucocorticoids.

In children who overdose causing early joints.

If used in combination with oral anticoagulants should regularly check prothrombin time to determine whether or not to adjust the dose or not.

Pregnant and lactating women.

To be out of reach of children.

The ability to drive and operate machinery

There is no data showing that the drug has an influence on the ability to drive and operate machinery. However, the unwanted effect of the drug is headache, insomnia, tremor, tachycardia that can occur. Therefore, need to be cautious when driving and operating machinery.

Pregnancy

thyroid hormones are not easy through the placenta fence. No effect on the fetus when the pregnant mother uses thyroid hormone. The treatment is still continued for women with thyroid disabilities because during pregnancy, the demand for levothyroxin may increase. The dose adjustment should be periodically tested by checking the concentration of TSH in serum.

Breastfeeding period

Small amount of thyroid hormone is excreted in milk. The drug does not cause harmful effects on children and does not cause tumors. However, it is necessary to be cautious when taking medicine for breastfeeding women.

Drug interaction

corticosteroids: The clearance through the metabolism of corticosteroids decreases in patients with hypothyroidism and increases in hyperthyroidism, so it can be changed along with the change of the thyroid gland. Must do the dose must be based on the results of the thyroid function assessment and the clinical status.

Amiodaron: Amiodaron alone can cause hyperthyroidism or hypothyroidism.

Anticoagulant, COMARIN or Indanodion derivatives: The effect of oral anticoagulants may be affected, depending on the patient's thyroid state, when increased thyroid hormone do the thyroid hormone may need to reduce anticoagulant dose, adjust the anticoagulant dose based on prothrombin time.

anti -diabetes or insulin: thyroid hormones may increase insulin or diabetes demand; Careful monitoring of diabetes control, when starting or when changing or stopping thyroid treatment.

Beta - Adrenegic blockers: The effect of some of these drugs is reduced when the patient has hypothyroidism in normal.

Cytokin (Interferon, Interleukin): can cause both hypothyroidism and hyperthyroidism.

Cardiac glycosides: The effect of these drugs may be reduced. Digitalis concentration in serum can be reduced in hyperthyroidism or in patients with hypothyroidism back to normal.

Ketamin: Causes hypertension and tachycardia if used simultaneously with levothyroxin.

maprotilin: The risk of arrhythmia can increase.

Sodium iodid (123i and 131i): The absorption of radioactive markers may be reduced.

Somatrem/somatropin: Timely use with too much thyroid hormone can quickly bone bone. Untreated hypothyroidism can affect the growth of these 2 drugs.

Theophylin: Theophylin's clearance decreases in people with hypothyroidism and returns to normal when the thyroid gland returns to normal.

3 -round antidepressants: simultaneous use will increase the effect and increase the toxicity of both drugs, possibly due to increased sensitivity to catecholamine. The effect of three -round depression can come sooner.

Sympathetic neuropathy: simultaneous use may increase the risk of coronary artery failure in patients with coronary artery.