Ladyvagi Phil Inter vaginal pellet treated on the spot of vaginitis (2 blisters x 6 tablets)

ATC code: G01AA51.

Neomycin is an aminoglycoside antibiotic that has a bactericidal effect through inhibiting bacterial protein biosynthesis, by attaching a 30S subunit of sensitive bacterial ribosom. Neomycin is mainly used to treat infections in the skin, ears, eyes caused by staphylococcus and other sensitive bacteria.

Nystatin is a polyene, anti -fungal antibiotic extracted from streptomyces noursei mushroom culture. Nystatin has the effect of restraining or eliminating fungi depending on the concentration and sensitivity of the fungus, not affecting the normal bacteria on the body. The most sensitive is yeast and has a very good effect on Candida Albicans. Nystatin tolerates well even when long -term treatment and does not cause drug resistance.

Polymyxin B has a bactericidal effect. The drug is attached to phospholipids that change the permeability and change the bacterial cell membrane structure, causing leaks of internal components.

Polymyxin B works on most Gram -negative bacteria, except Proteus spp .. Polymyxin B is used on the spot, often in combination with other drugs to treat skin, eyes, ears and some other bacterial infections caused by sensitive bacteria.

Dynamic pharmacokinetics

Neomycin is poorly absorbed through the gastrointestinal tract (3%), about 97% of oral dose is excreted in the form of unchanged in feces. The absorption of drugs may increase when the mucosa is inflamed or damaged.

When absorbed, the drug will quickly excreted through the kidneys in the form of activity. The sale time of the drug is about 2-3 hours.

About 0 - 30% of the drug is attached to protein, the integral distribution of 0.36 liters/kg.

Nystatin is poorly absorbed through the gastrointestinal tract, not absorbed through the skin or mucosa when used on the spot, excreting mainly in the feces in the form of unprocessed.

Polymyxin B Sulfate absorbs well through the peritoneal; do not absorb through the gastrointestinal tract; Not significantly absorbed through the mucosa and skin intact or peeling off the outer coating as in the case of severe burns.

put 1 capsule deep inside the vagina, for 12 days. It will be more convenient and easier when placing the drug in the back, two pillows.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when using overdose?

Consult medical staff and actively monitor for timely management measures.

In case of emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double doses to compensate for missed dose.

Be cautious when using

Attention

Hypersensitivity to an antibiotic when used on the spot can adversely affect the use of that antibiotic or an antibiotic similar to the future system.

Be cautious when using

Do not treat long -term due to the risk of selecting resistance strains and the risk of superinfection caused by these pathogens.

Due to the lack of data on the level of absorption through the mucosa of Neomycin and Polymyxin B, it is not possible to eliminate the body's body effect.

Although there has been no recognition of the adverse effects on the whole body of the drug, it is also important to pay attention to this, especially in patients with renal failure.

The effect of the drug on driving and operating machinery

Ladyvagi does not affect the ability to drive and operate machinery.

Use drugs for women during pregnancy and lactation

Pregnancy: During pregnancy, this drug should not be used.

Breastfeeding period: During breastfeeding, should avoid using this medication.

Drug interaction

Do not share this drug with spermicide (because of the risk of active loss) and contraceptives.