Lamisil Novartis skin cream treats skin fungal infections, tinea versicolor (5g)

Dosage form Tube
Specifications Terbinafine hydrochloride

Ingredient

Thành phần cho 1g

Composition information	Content
Terbinafine hydrochloride	10mg

Uses

Indications

Lamisil 5G medicine are indicated in the following cases:

Skin fungal infections caused by Dermatophytes such as Trichophyton (for example, T. rubrum, T.mentagrophytes, T. Verrucosum, T.Violaceum), Microsporum Canis and Epidermophyton Flocosum, such as interstitial fungal fungus (athletes), fungal disease in Dhobie (Jock). And fungal disease causes round array damage.

versicolor due to Pityrosporum Orbiculare (also known as Malassezia Furfur).

Yeast infections in the skin, mainly caused by Candida (such as Candida albicans).

Fungal fungal infection.

Pharmacy

terbinafine is a Alxylamine with anti -fungal activity in skin infections caused by Dermatophytes as Trichophyton (for example, Rubrum, Mentagrophytes, T. Verrucosum, Violaceum), Microrum Canis and Canis and Canis and Canis and Canis and Canis and Canis and Canis and Canis and Canis Epidermophyton Flocosum.

In low concentrations, Terbinafine kill dermatophytes, mold and some bipolar mushrooms. Anti -fungal activity is fungicide (eg pityrosporum orbiculare or malassezia furfur) or mushroom pliers, depending on the type of mushroom.

Terbinafine has a long -lasting effect, less than 10% of people with foot fungus (Athlete's Foot) are treated with 1% Terbinafine cream in 1 week with a relapse or re -infection at 3 months after the beginning of treatment.

terbinafine intervenes specially in the mushroom biosynthesis process in the original step. This leads to the deficiency of Ergosterol and the accumulation of squalene in the cell, leading to the death of the fungal cells.

Terbinafine acts by inhibiting Squalene Epoxidase in the fungal cell membrane. The enzyme Squalene Epoxidase is not associated with the Cytochrome P450 system. Terbinafine does not affect the metabolism of hormones or other drugs.

pharmacokinetics

absorption:

On humans, less than 5% of the dose is absorbed after local use, so the body contact level is very low.

Distribution:

After 7 days of using Lamisil cream, the terbinafine concentration exceeds the concentration needed for the fungic activity in the horny layer of the disease for at least 7 days after the stop treatment.

Metabolism and elimination:

No report.

Before taking Lamisil Novartis skin cream treats skin fungal infections, tinea versicolor (5g)

How to use

only use on the skin. Before the first use, the sealing membrane of the tube must be punctured using the pointed point of the screw cap.

The sick area needs to be cleaned and dried thoroughly before applying the drug.

Apply a thin layer of cream to the sick and surrounding skin and rub gently.

In case of fungal infections in the skin frequently rubbing each other (under the breast, interstitial, buttocks, groin), the topical area can be covered with a piece of gauze, especially at night.

Dosage

Adults and children aged 12 and older:

Time and frequency of treatment:

Fungal fungus (feet of fingers): 1 time/day for 1 week.

Fungal fungus: 2 times/day for 2 weeks.

Fungal disease in the skin is wet and fungal disease causes round array damage: 1 time/day for 1 week.

Candida fungus in the skin: 1 or 2 times/day for 1-2 weeks.

Visitors: 1 or 2 times/day for 2 weeks.

Clinical symptoms usually begin to improve within a few days. Non -regular use or premature treatment leads to the risk of recurrence. If there is no sign of improvement after 2 weeks, patients should see a doctor or pharmacist to verify the diagnosis.

Take drugs in special patients:

Children:

Do not recommend the use of drugs for children under 12 years of age because there is not enough data on safety and efficiency.

Elderly patients:

There is no evidence that elderly patients need other doses or have other side effects than younger patients.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Inadvertently swallowed a 30g lamisil cream tube containing 300mg of Terbinafine Hydrochloride equivalent to taking a 250mg lamisil tablet (the dose of orally in adults). These adverse effects include headaches, nausea, epigastric pain and dizziness.

Overdose treatment: Handling should be clinically or recommended by national toxic anti -toxic centers.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Lamisil 5G, you may experience unwanted effects (ADR).

Popular symptoms such as itching, peeling skin, pain in the top of the drug, the drug irritation, pigmentation disorders, hot sensation in the skin, erythema, scales, etc. can occur at the top of the drug.

It is necessary to distinguish these mild symptoms from hypersensitive reactions including the rash that is reported in sporadic cases and need to stop treatment. In the case of unintentional eyes, Terbinafine Hydrochloride can cause eye irritation.

Common, ADR> 1/100

Skin and subcutaneous tissue disorders: peeling skin, itching.

Uncommon, 1/1000

Skin and tissue disorders: Skin damage, scales, skin disorders, pigmentation disorders, erythema, hot sensation in the skin.

Systemic disorders and the condition of the drug: Pain, pain at the top of the drug, irritation at the top of the drug.

Rare, 1/10000

Skin and tissue disorders: Dry skin, contact dermatitis , eczema (Eczema).

Eye disorders: eye irritation.

Systemic disorders and the condition of the drug: The condition of severe illness.

Unknown frequency

Skin disorders and subcutaneous tissue: rash.

immune system disorders: Hypersensitivity.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Lamisil 5g drug contraindicated in the following case:

Patients with a history of hypersensitivity to terbinafine or any excipients of the drug.

Caution when using

can irritate the eye. In case of unintentional drugs to stick to the eyes, wash the eyes under the tap.

Must be out of reach of children.

Babies must not be exposed to any skin treatment, including breast fish.

Only external use.

If applying the medicine on the face, stay away from the eyes.

Lamisil 5g cream contains Cetyl and Stearyl alcohol, which can cause local skin reactions (for example, contact dermatitis).

The ability to drive and operate machinery

topical skin terbinafine does not affect the ability to drive and operate machinery.

Pregnancy

There is no clinical experience with terbinafine in pregnant women. Animal toxicity studies in animals show that there is no harm to pregnancy or fetal health. However, should not be used during pregnancy unless it is really necessary.

The period of breastfeeding

terbinafine is excreted into breast milk. After use on the spot, it is expected to be exposed to low systems. terbinafine should only be used for breastfeeding women if the expected benefits are superior to the risk of babies. In addition, babies are not allowed to be exposed to any skin that is applied, including breasts.

Drug interaction

There is no clinical -related drug interaction.

Storage

Do not store over 300C.

Keep the drug in the original packaging.

Other drugs

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